Experimental & Clinical Epilepsy and Related Comorbidities

Experimental & Clinical Epilepsy and Related Comorbidities
Author: Mohd Farooq Shaikh
Publisher: Frontiers Media SA
Total Pages: 129
Release: 2020-12-02
Genre: Science
ISBN: 2889661466

Download Experimental & Clinical Epilepsy and Related Comorbidities Book in PDF, Epub and Kindle

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Experimental Models of Epilepsy and Related Comorbidities

Experimental Models of Epilepsy and Related Comorbidities
Author: Mohd. Farooq Shaikh
Publisher: Frontiers Media SA
Total Pages: 175
Release: 2019-06-19
Genre:
ISBN: 2889458431

Download Experimental Models of Epilepsy and Related Comorbidities Book in PDF, Epub and Kindle

Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved in studying the disease and its comorbid effects. Various experimental models are used to understand the mechansims of disease and to discover newer antiepileptic drugs. These experimental models combines the input from behavioral, biochemical and molecular level including genetic.

The Comorbidities of Epilepsy

The Comorbidities of Epilepsy
Author: Marco Mula
Publisher: Academic Press
Total Pages: 413
Release: 2019-04-20
Genre: Medical
ISBN: 0128148780

Download The Comorbidities of Epilepsy Book in PDF, Epub and Kindle

Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers. Provides a comprehensive overview of somatic, neurological and behavioral co-morbidities of epilepsy Discusses up-to-date management of comorbidities of epilepsy Written by a group of international experts in the field

Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies
Author: Jeffrey Noebels
Publisher: OUP USA
Total Pages: 1258
Release: 2012-06-29
Genre: Medical
ISBN: 0199746540

Download Jasper's Basic Mechanisms of the Epilepsies Book in PDF, Epub and Kindle

Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Epilepsy and the Interictal State

Epilepsy and the Interictal State
Author: Erik K. St Louis
Publisher: John Wiley & Sons
Total Pages: 289
Release: 2015-03-16
Genre: Medical
ISBN: 0470656239

Download Epilepsy and the Interictal State Book in PDF, Epub and Kindle

Epilepsy care traditionally focuses on seizures, yet for most epilepsy sufferers, other interictal factors such as mood, cognitive abilities, and treatment adverse effects most influence how they feel and function day to day. Epilepsy and the Interictal State is a practical and comprehensive text that covers quality of life issues, cognition and therapy, adverse effects of epilepsy treatments, mood state and psychiatric co-morbidity and general health aspects of epilepsy. Each chapter employs a standard structure providing background, epidemiology, pathophysiology, etiology, diagnosis, treatment, prognosis and further practical advice. From an international team of expert editors and contributors, Epilepsy and the Interictal State is a valuable resource for specialist epileptologists and neurologists, as well as for neurosurgeons, neurology nurses, psychiatrists, family physicians and general practitioners.

Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
Author: Asla Pitkänen
Publisher: Academic Press
Total Pages: 1180
Release: 2017-06-14
Genre: Medical
ISBN: 012804067X

Download Models of Seizures and Epilepsy Book in PDF, Epub and Kindle

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Febrile Seizures

Febrile Seizures
Author: Tallie Z. Baram
Publisher: Academic Press
Total Pages: 370
Release: 2022-09-20
Genre: Medical
ISBN: 0323984185

Download Febrile Seizures Book in PDF, Epub and Kindle

Febrile seizures are the most common seizures in infants and children worldwide, This fact provides strong impetus to study and understand them and their consequences, and consider their treatment. These topics were the focus of the first edition of this book. The 20 years since the publication of this first edition have witnessed an explosion of new information about febrile seizures, meriting this new edition. Key advances have been made in the genetics and neurobiological underpinnings of febrile seizures and especially the very long fever-related seizures called febrile status epilepticus. The role of neuroinflammatory factors in the emergence of these seizures and their consequences, the demonstration of unique clinical and neuroradiological aspects of febrile status epilepticus, and the prospect of predictive (bio)markers to identify and characterize cognitive and epilepsy outcomes are exciting and important. In this edition, the authors and editors tackle these developments in chapters addressing the questions of parents, physicians, allied health care professionals and basic and translational scientists. Reviews all aspects of febrile seizures, including epidemiology, neurobiology and treatment Discusses novel and newly discovered information based on up-to the minute methods Provides an engaging style that is accessible to clinicians, researchers and educated parents

The Causes of Epilepsy

The Causes of Epilepsy
Author: Simon Shorvon
Publisher: Cambridge University Press
Total Pages: 1013
Release: 2019-05-02
Genre: Medical
ISBN: 1108420753

Download The Causes of Epilepsy Book in PDF, Epub and Kindle

Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.

The Falling Sickness

The Falling Sickness
Author: Owsei Temkin
Publisher: JHU Press
Total Pages: 530
Release: 1994-03-01
Genre: Medical
ISBN: 1421400537

Download The Falling Sickness Book in PDF, Epub and Kindle

"A thoroughly admirable and informative introduction to our knowledge of epilepsy in the Western world from antiquity to the early twentieth century." - American Scientist Owsei Temkin presents the history of epilepsy in Western civilization from ancient times to the beginnings of modern neurology. First published in 1945 and thoroughly revised in 1971, this classic work by one of the history of medicine's most eminent scholars now returns to print available in both paperback and eBook formats.

Epilepsy Across the Spectrum

Epilepsy Across the Spectrum
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 568
Release: 2012-07-29
Genre: Medical
ISBN: 0309259533

Download Epilepsy Across the Spectrum Book in PDF, Epub and Kindle

Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.