Evaluating Evidence of Mechanisms in Medicine

Evaluating Evidence of Mechanisms in Medicine
Author: Veli-Pekka Parkkinen
Publisher: Springer
Total Pages: 131
Release: 2018-07-13
Genre: Medical
ISBN: 3319946102

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This book is open access under a CC BY license. This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness. Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions. The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.

Evaluating Evidence in Biological Anthropology

Evaluating Evidence in Biological Anthropology
Author: Cathy Willermet
Publisher: Cambridge University Press
Total Pages: 231
Release: 2019-11-14
Genre: Science
ISBN: 1108476848

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A critical assessment of how evidence in biological anthropology is discovered, collected and interpreted.

Finding and Evaluating Evidence

Finding and Evaluating Evidence
Author: Denise E. Bronson
Publisher: Oxford University Press
Total Pages: 110
Release: 2012
Genre: Political Science
ISBN: 0195337360

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"This pocket guide provides a concise overview of how to complete a systematic review, and criteria that should be used for assessing the quality of existing reviews. It examines evidence-based practice, systematic reviews, and meta-analysis."--WorldCat.

Evaluating Evidence

Evaluating Evidence
Author: George Akita
Publisher: University of Hawaii Press
Total Pages: 290
Release: 2008-05-20
Genre: History
ISBN: 0824825608

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Evaluating Evidence is based on the grueling lessons learned by a senior scholar during three decades of tutoring by, and collaboration with, Japanese historians. George Akita persisted in the difficult task of reading documentary sources in Japanese, most written in calligraphic style (sôsho), out of the conviction of their centrality to the historian’s craft and his commitment to a positivist methodology to research and scholarship. He argues forcefully in this volume for an inductive process in which the scholar seeks out facts on a subject and, through observation and examination of an extensive body of data, is able to discern patterns until it is possible to formulate certain propositions. In his introduction, Akita relates how and why he decided to adopt a positivist approach and explains what he means by the term as it applies to humanistic studies. He enumerates the difficulties linked with reading primary sources in Japanese by looking at a variety of unpublished and published materials and identifying a major problem in reading published primary sources: the intervention of editors and compilers. He illustrates the pitfalls of such intervention by comparing the recently published seventeen-volume diary of Prime Minister Hara Takashi (1856–1921), a photo reproduction of the diary in Hara’s own hand, and an earlier published version. Using documents related to Yamagata Aritomo (1838–1922), a figure of central importance in Japan’s post-Restoration political history, he demonstrates the use of published and transcribed primary sources to sustain, question, or strengthen some of the themes and approaches adopted by non-Japanese scholars working on modern Japanese history. He ends his inquiry with two "case studies," examining closely the methods of the highly acclaimed American historians John W. Dower and Herbert P. Bix.

Evaluating Evidence

Evaluating Evidence
Author: George Akita
Publisher: University of Hawaii Press
Total Pages: 290
Release: 2008-05-20
Genre: History
ISBN: 0824862422

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Evaluating Evidence is based on the grueling lessons learned by a senior scholar during three decades of tutoring by, and collaboration with, Japanese historians. George Akita persisted in the difficult task of reading documentary sources in Japanese, most written in calligraphic style (sôsho), out of the conviction of their centrality to the historian’s craft and his commitment to a positivist methodology to research and scholarship. He argues forcefully in this volume for an inductive process in which the scholar seeks out facts on a subject and, through observation and examination of an extensive body of data, is able to discern patterns until it is possible to formulate certain propositions. In his introduction, Akita relates how and why he decided to adopt a positivist approach and explains what he means by the term as it applies to humanistic studies. He enumerates the difficulties linked with reading primary sources in Japanese by looking at a variety of unpublished and published materials and identifying a major problem in reading published primary sources: the intervention of editors and compilers. He illustrates the pitfalls of such intervention by comparing the recently published seventeen-volume diary of Prime Minister Hara Takashi (1856–1921), a photo reproduction of the diary in Hara’s own hand, and an earlier published version. Using documents related to Yamagata Aritomo (1838–1922), a figure of central importance in Japan’s post-Restoration political history, he demonstrates the use of published and transcribed primary sources to sustain, question, or strengthen some of the themes and approaches adopted by non-Japanese scholars working on modern Japanese history. He ends his inquiry with two "case studies," examining closely the methods of the highly acclaimed American historians John W. Dower and Herbert P. Bix.

Finding and Evaluating Evidence

Finding and Evaluating Evidence
Author: Denise E. Bronson
Publisher: Oxford University Press
Total Pages: 110
Release: 2011-09-22
Genre: Social Science
ISBN: 0199714053

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Evidence-based practice (EBP) promises to have a profound impact on social work practice, education, and scholarship, but adopting EBP depends on the availability and accessibility of evidence and on strategies to synthesize this information. Systematic reviews provide a comprehensive, unbiased method for retrieving and synthesizing relevant research. This pocket guide is a concise introduction that describes the steps required to complete a systematic review and the criteria that can be used to assess the quality of existing reviews. The authors provide straightforward information on how to define a search question that captures the problem's parameters, develop a search strategy that is transparent and comprehensive, assess the quality and credibility of existing research, and summarize the available research to support EBP in social work. Providing coverage for both quantitative and qualitative synthesis methods, examples illustrate the steps and decisions associated with each approach to research synthesis. Key points and suggested readings and websites provide avenues for further study. This pocket guide is an excellent introduction to EBP and systematic reviews that will be valued by social work students, practitioners, and scholars.

Interpreting Evidence

Interpreting Evidence
Author: Bernard Robertson
Publisher: John Wiley & Sons
Total Pages: 216
Release: 2016-07-28
Genre: Medical
ISBN: 1118492455

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This book explains the correct logical approach to analysis of forensic scientific evidence. The focus is on general methods of analysis applicable to all forms of evidence. It starts by explaining the general principles and then applies them to issues in DNA and other important forms of scientific evidence as examples. Like the first edition, the book analyses real legal cases and judgments rather than hypothetical examples and shows how the problems perceived in those cases would have been solved by a correct logical approach. The book is written to be understood both by forensic scientists preparing their evidence and by lawyers and judges who have to deal with it. The analysis is tied back both to basic scientific principles and to the principles of the law of evidence. This book will also be essential reading for law students taking evidence or forensic science papers and science students studying the application of their scientific specialisation to forensic questions.

Evaluating Research for Evidence-Based Nursing Practice

Evaluating Research for Evidence-Based Nursing Practice
Author: Jacqueline Fawcett
Publisher: F.A. Davis
Total Pages: 337
Release: 2008-08-22
Genre: Medical
ISBN: 0803622287

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Where is the evidence in a nursing research study? What is the evidence? How good is the evidence? And, how is it relevant to providing evidence-based nursing care? Ensure that students can meet the AACN’s (American Association of Colleges of Nursing) goal of identifying valid research findings and using them to determine if they are providing care that is supported by evidence.

Impact Evaluation in Practice, Second Edition

Impact Evaluation in Practice, Second Edition
Author: Paul J. Gertler
Publisher: World Bank Publications
Total Pages: 444
Release: 2016-09-12
Genre: Business & Economics
ISBN: 1464807809

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The second edition of the Impact Evaluation in Practice handbook is a comprehensive and accessible introduction to impact evaluation for policy makers and development practitioners. First published in 2011, it has been used widely across the development and academic communities. The book incorporates real-world examples to present practical guidelines for designing and implementing impact evaluations. Readers will gain an understanding of impact evaluations and the best ways to use them to design evidence-based policies and programs. The updated version covers the newest techniques for evaluating programs and includes state-of-the-art implementation advice, as well as an expanded set of examples and case studies that draw on recent development challenges. It also includes new material on research ethics and partnerships to conduct impact evaluation. The handbook is divided into four sections: Part One discusses what to evaluate and why; Part Two presents the main impact evaluation methods; Part Three addresses how to manage impact evaluations; Part Four reviews impact evaluation sampling and data collection. Case studies illustrate different applications of impact evaluations. The book links to complementary instructional material available online, including an applied case as well as questions and answers. The updated second edition will be a valuable resource for the international development community, universities, and policy makers looking to build better evidence around what works in development.

The Evaluation of Forensic DNA Evidence

The Evaluation of Forensic DNA Evidence
Author: National Research Council
Publisher: National Academies Press
Total Pages: 270
Release: 1996-12-12
Genre: Science
ISBN: 0309134404

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In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.