EPITHELIAL-MESENCHYMAL INTERAC

EPITHELIAL-MESENCHYMAL INTERAC
Author: 陳德華
Publisher: Open Dissertation Press
Total Pages: 208
Release: 2017-01-27
Genre: Medical
ISBN: 9781374731363

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This dissertation, "Epithelial-mesenchymal Interactions in Development and Cytodifferentiation of Seminal Vesicle" by 陳德華, Tak-wah, Chan, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b3121123 Subjects: Epithelium Mesenchyme Seminal vesicles

Mesenchymal-Epithelial Interactions in Neural Development

Mesenchymal-Epithelial Interactions in Neural Development
Author: Joachim R. Wolff
Publisher: Springer Science & Business Media
Total Pages: 424
Release: 2013-06-29
Genre: Science
ISBN: 364271837X

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This book is based on the NATO Advanced Research Workshop on "Mesenchymal-Epithelial Interactions in Neural Development" which was held in Berlin during March 1986. The idea that it may be the time for this workshop arose from a discussion among the organizers who met at a conference in Innsbruck. During the twenties, Spemann demonstrated that, in vertebrates, the formation of neuroepithelium depends on the induction by specific mesodermal derivatives. This was about the first time that mesenchymal-epithelial interactions had been recognized as an important mechanism in the development of an epithelial organ. Since then two things had become clear: 1) The identity and role of molecules, elaborated at mesenchymal-neuroepithelial interfaces had been partially elucidated in spinal cord and peripheral nerve ontogeny but, until recently, had been ignored in studies on the development of the brain. 2) In many-non-neural epithelia, the surrounding mesenchyme regulates such fundamental developmental steps as, for example, cell proliferation, morphogenesis and cell differentia tion, and there is no reason to exclude similar influences and interactions from brain development. It seemed to us that the importance and implications of many of these findings had not been appreciated by many developmental neurobiologists and that an attempt should be made to initiate discussions and exchange of ideas among different groups of scientists involved in extracellular matrix (ECM) research. This turned out to be a formidable task because of the great diversity of disciplines contributing findings to this active field.

Regulatory Mechanisms in Breast Cancer

Regulatory Mechanisms in Breast Cancer
Author: Marc E. Lippman
Publisher: Springer Science & Business Media
Total Pages: 455
Release: 2012-12-06
Genre: Medical
ISBN: 1461539404

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In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was superb, indicating a tremendous interest in basic growth regulatory mechanisms governing breast cancer and controlling its malignant progres sion. In the two years since its publication, much new and exciting in formation has been published and the full interplay of regulatory mechanisms is now beginning to emerge. We have divided this book into four sections that we hope will unify important concepts and help to crystallize areas of consensus and/or disagreement among a diverse group of basic and clinical scientists working on the disease. The first section is devoted to studies on oncogenes, antioncogenes, proliferation, and tumor prognosis. The first chapter, by Sunderland and McGuire, introduces the characteristics of breast cancer as studied by patho logists to establish prognostic outcome. Of particular interest is a new proto oncogene called HER-2 (or neu), which is rapidly becoming accepted as a valuable new tumor marker of poor prognosis. The second chapter, by Lee Bookstein and Lee, introduces the best known antioncogene, the retinoblas toma antioncogene, whose expression is sometimes lost in breast cancer. Malignant progression appears to be influenced by the balance of proto oncogene and antioncogene expression.

Prostate Cancer - Clinical And Scientific Aspects: Bridging The Gap

Prostate Cancer - Clinical And Scientific Aspects: Bridging The Gap
Author: Paul David Abel
Publisher: World Scientific
Total Pages: 1255
Release: 2003-12-01
Genre: Medical
ISBN: 1783261196

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Despite the advent of the genomic era, the perceived benefits of close collaboration between clinicians and scientists are not always realised and the gap between bench and bedside remains. Closer collaboration should expedite advances in treating disease. This important book, with a foreword by Fritz H Schröder, is designed to enhance the relationship between the two communities. It contains data from a multinational authorship, the thirty-eight chapters being written by experts with widely differing training and expectations. Their aim is to facilitate both understanding and in-depth knowledge of their subject. By bridging the gap between clinicians and scientists, the hope is to enhance translational research in their common goal of improving the diagnosis and treatment of prostate cancer, the single most important cancer affecting men./a

Growth Factors and the Ovary

Growth Factors and the Ovary
Author: Anne N. Hirshfield
Publisher: Springer Science & Business Media
Total Pages: 440
Release: 2013-06-29
Genre: Medical
ISBN: 1468456881

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The First Ovarian Workshop was held in June 1976; its goal was to achieve a collective understanding of current thought on ovarian follicular development and function, and to generate clear definitions of the most important areas to be explored in the future. The Ovarian Workshops quickly became a major biennial event for the community of reproduc tive biologists and their students studying ovarian function. As a young graduate student, I gave my first scientific presentation at the First Ovarian Workshop and I have attended all but one of the subsequent meetings. The Workshops provided a unique forum for the sharing ofideas with colleagues studying closely related problems. I was therefore especially pleased to have been asked to organize the Seventh Ovarian Workshop and to be given an opportunity to help perpetuate these important meetings. The Seventh Ovarian Workshop was held on the campus of the University of Puget Sound in Tacoma, Washington on July 31 and August 1, 1988. Serono Symposia USA generously financed and coordinated the meeting. I would like to express my particular thanks to Dr. L. Lisa Kern and Dr. James Posillico for their invaluable help prior to, during, and after the meeting. I would also like to thank Mary Benson and her staff at the University of Puget Sound who made us feel at home in every way.

Autocrine and Paracrine Mechanisms in Reproductive Endocrinology

Autocrine and Paracrine Mechanisms in Reproductive Endocrinology
Author: L. Krey
Publisher: Springer Science & Business Media
Total Pages: 208
Release: 2013-11-11
Genre: Science
ISBN: 1468457519

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There is a prov1s10n in the charter of each Study Section of the Division of Research Grants at the National Institutes of Health that stipulates that "workshops" are to be held periodically to aid Study Section members in their appraisals of recent developments in their fields and to identify future challenges worthy of investigation. The Reproductive Endocrinology Study Section was established on December 13, 1985 to review research grants and research training activities relating to reproductive endocrinology, including aspects of management of reproductive endocrine disorders and hormonal imbalances as related to infertility and during pregnancy and puberty, breast cancer and prostate cancer. It held its first workshop, entitled, "Autocrine and Paracrine Mechanisms in Reproductive Endocrinology," in October, 1988 in Shrewsbury, MA at The Worcester Foundation for Experimental Biology. The proceedings of this workshop, which are detailed herein, reflect the fact that autocrine and paracrine interactions are rapidly being accepted as an exciting area of research by scientists investigating the physiological and biochemical mechanisms of hormone action in the male and female reproductive systems. The material covered is novel and wide-ranging, extending from theoretical considerations of mechanisms of growth factor action and the role of cell cycle stage in determining hormone action to investigations of autocrine and paracrine interactions during development to discussions of the potential clinical ramifications of the basic research findings. Such an extensive inventory is necessary for two reasons.

Textbook of Benign Prostatic Hyperplasia, Second Edition

Textbook of Benign Prostatic Hyperplasia, Second Edition
Author: Roger S. Kirby
Publisher: CRC Press
Total Pages: 594
Release: 2004-11-29
Genre: Medical
ISBN: 9781901865554

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Completely revised and updated, Textbook of Benign Prostatic Hyperplasia, Second Edition provides a state-of-the-art overview of the entire field. The first edition of this breakthrough book was very well received by urologists around the world and became the standard reference work on the subject of Benign Prostatic Hyperplasia (BPH). With the constant changes and improvements being made in therapeutics and treatment in general, any book on this important subject needs to be updated frequently. The first edition's original sections have been expanded and, once again, a team of expert editors and contributors ensure that the material presented reflects the latest available information.The editorial panel examines all aspects of the disorder, from pathophysiology to the latest treatments and clinical trials including MTOPS and PREDICT. They explore laser prostatectomy using the holmium laser and a host of other minimally invasive techniques that are seriously challenging standard transurethral resection (TUR) as the gold standard intervention for this disease. Building on the foundation of the first edition, this second edition will continue to be the quintessential resource on BPH.

Pediatric Andrology

Pediatric Andrology
Author: S.J. Kogan
Publisher: Springer Science & Business Media
Total Pages: 220
Release: 2012-12-06
Genre: Medical
ISBN: 9401037191

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The subject matter in this volume was derived from papers presented at the Pediatric Andrology session of the 1st Pan American Congress of Andrology held in Caracas, Venezuela in February 1979, as well as from selected additional manuscripts of interest in this field. Prior to this session, identification of a distinct discipline and specialty devoted to pediatric andrology had not occurred, nor had it been conceptualized. Pediatric andrology encompasses many different areas: disorders of sexual development, structural disease of the genital organs, normal and abnormal puberty, undescended testes, genital tumors, gonadal function and its relationship to growth, virilization, fertility and gender identity all represent areas of specific interest, to name but a few. Andrology itself is a unique field, bringing together clinicians and basic scientists with diverse back grounds. It should be noted that between one-half and three-quarters of the clinicians contributing to this issue conduct basic research as well. It has been this unique blend of basic research and clinical medicine which has done much to unravel many of these problems characteristic of this field.