Enantioselective Synthesis of Beta-Amino Acids

Enantioselective Synthesis of Beta-Amino Acids
Author: Eusebio Juaristi
Publisher: John Wiley & Sons
Total Pages: 658
Release: 2005-05-06
Genre: Science
ISBN: 0471698474

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Covers all facets of the synthesis of ß-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ß-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ß-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ß-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ß-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ß-amino acid targets and salient ß-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ß-amino acids * Includes general and practical procedures for the preparation of ß-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ß-amino acids * Includes a report on the preparation of libraries of enantiopure ß-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ß-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.

Enantioselective Synthesis of ß-Amino Acids

Enantioselective Synthesis of ß-Amino Acids
Author: Eusebio Juaristi
Publisher: Wiley
Total Pages: 0
Release: 1996-12-27
Genre: Science
ISBN: 9780471186274

Download Enantioselective Synthesis of ß-Amino Acids Book in PDF, Epub and Kindle

This book presents an overview of the importance of ß-amino acids in pharmaceutical sciences, and discusses the most important methods that have been developed for the preparation of enantiomerically pure compounds. Each method is described by the organic chemist who developed it, and so will be written with authoritative, first-hand knowledge. This title is the first book to summarize new available methodologies for preparing ß-amino acids in optically pure form, a recent development in this field. The title also provides methods for synthesizing optically pure precursors to pharmacologically active substances, including ß-lacatams.