"The Point Collocation Non-Intrusive Polynomial Chaos (NIPC) method was applied to a stochastic synthetic jet actuator problem to demonstrate the integration of computationally efficient uncertainty quantification to the high-fidelity CFD modeling of Synthetic Jet Actuators. The uncertainty quantification approach was first implemented in two stochastic model problem cases for the prediction of peak exit plane velocity using a Fluid Dynamic Based analytical model of the Synthetic Jet Actuator, which is computationally less expensive than CFD simulations. The NIPC results were compared with direct Monte Carlo sampling results. To demonstrate the efficient uncertainty quantification in CFD modeling of synthetic jet actuators, a test case, Case 1 (synthetic jet issuing into quiescent air), was selected from the CFDVal2004 workshop. In the stochastic CFD problem, the NIPC method was used to quantify the uncertainty in the long-time averaged u and v-velocities at several locations in the flow field, due to the uncertainty in the amplitude and frequency of the oscillation of the piezo-electric membrane. Fifth order NIPC expansions were used to obtain the uncertainty information which showed that the variation in the v-velocity is high in the region directly above the jet slot and the variation in the u-velocity is maximum in the region immediately adjacent to the slot. Even with a ten percent variation in the amplitude and frequency, the long-time averaged u and v-velocity profiles could not match the experimental measurements at y = 0.1mm above the slot, indicating that the discrepancy may be due to other uncertainty sources in CFD or measurement errors. A global sensitivity analysis using linear regression approach indicated that the frequency had a stronger contribution to the overall uncertainty in the long-time averaged flow field velocity for the range of input uncertainties considered in this study. Overall, the results obtained in this study showed the potential of Non-Intrusive Polynomial Chaos as an effective uncertainty quantification method for computationally expensive high-fidelity CFD simulations applied to the stochastic modeling of synthetic jet flow fields"--Abstract, leaf iii.