Drug Synthesis Book Set

Drug Synthesis Book Set
Author: Jie Jack Li
Publisher: John Wiley & Sons
Total Pages: 0
Release: 2015-11-23
Genre: Science
ISBN: 9781119185659
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This set presents the authoritative and acclaimed Drug Synthesis books edited by Jie Jack Li and Douglas Johnson: Contemporary Drug Synthesis, The Art of Drug Synthesis, Modern Drug Synthesis, and Innovative Drug Synthesis. This book set will be enormously useful to pharmaceutical industry labs, research scientists in lead optimization and process development, and graduate students and courses in organic chemistry, synthetic organic chemistry, heterocyclic chemistry, medicinal chemistry, and drug synthesis courses.

The Art of Drug Synthesis

The Art of Drug Synthesis
Author: Douglas S. Johnson
Publisher: John Wiley & Sons
Total Pages: 295
Release: 2013-02-26
Genre: Science
ISBN: 111867846X
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The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-selling drugs on the market today. An introduction to each drug is provided, as well as background to the biology, pharmacology, pharmacokinetics, and drug metabolism, followed by a detailed account of the drug synthesis. Edited by prominent scientists working in drug discovery for Pfizer Meets the needs of a growing community of researchers in pharmaceutical R&D Provides a useful guide for practicing pharmaceutical scientists as well as a text for medicinal chemistry students An excellent follow-up to the very successful first book by these editors, Contemporary Drug Synthesis, but with all new therapeutic categories and drugs discussed.

Innovative Drug Synthesis

Innovative Drug Synthesis
Author: Jie Jack Li
Publisher: John Wiley & Sons
Total Pages: 358
Release: 2015-11-05
Genre: Science
ISBN: 1118820088
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This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting-edge science associated with them. Following the editors’ 3 successful drug synthesis books, this provides expert analysis of the pros and cons of different synthetic routes and demystifies the process of modern drug discovery for practitioners and researchers. Summarizes for each drug: respective disease area, important properties and SAR (structure-activity relationship), and chemical synthesis routes / options Includes case studies in each chapter Illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines Explains the advantages of process synthesis versus the synthetic route for drug discovery

The Organic Chemistry of Drug Synthesis, 6 Volume Set

The Organic Chemistry of Drug Synthesis, 6 Volume Set
Author: Daniel Lednicer
Publisher: Wiley-Interscience
Total Pages: 0
Release: 1998-11-18
Genre: Science
ISBN: 9780471333708
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Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Modern Drug Synthesis

Modern Drug Synthesis
Author: Jie Jack Li
Publisher: John Wiley & Sons
Total Pages: 371
Release: 2013-03-27
Genre: Science
ISBN: 1118701240
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Following Contemporary Drug Synthesis and The Art of Drug Synthesis (Wiley, 2004 and 2007), two well-received works, is this new book that demystifies the process of modern drug discovery for practitioners and students. An enhanced introduction covers areas such as background, pharmacology, SAR, PK/PD, efficacy, and safety. Focusing on the advantages of process synthesis versus the discovery synthetic route, Modern Drug Synthesis features authoritative coverage by distinguished editors and authors (some chapter authors are the actual inventor of the drug) of twenty different drug molecules.

An Introduction to Drug Synthesis

An Introduction to Drug Synthesis
Author: Graham L. Patrick
Publisher: Oxford University Press, USA
Total Pages: 587
Release: 2015
Genre: Medical
ISBN: 0198708432
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Introduction to Drug Synthesis explores the central role played by organic synthesis in the process of drug design and development - from the generation of novel drug structures to the improved efficiency of large scale synthesis.

The Organic Chemistry of Drug Synthesis, 4 Volume Set

The Organic Chemistry of Drug Synthesis, 4 Volume Set
Author: Daniel Lednicer
Publisher: Wiley-Interscience
Total Pages: 0
Release: 1991-01-16
Genre: Science
ISBN: 9780471531760
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Updated every five years, the series represents the optimal compromise between currency and a sufficient body of material for cohesive and comprehensive treatment in a monograph. Provides a quick yet thorough overview of the synthetic routines that have been used to access specific classes of therapeutic agents. Materials are organized by chemical class, and syntheses are taken back to available starting materials. Discusses disease state, rational for method of drug therapy, biological activities of each compound and preparation. Coverage also includes those generic pharmaceutical compounds not accorded clinical status. A glossary defines biological terms.

Strategies for Organic Drug Synthesis and Design

Strategies for Organic Drug Synthesis and Design
Author: Daniel Lednicer
Publisher: John Wiley & Sons
Total Pages: 700
Release: 2009-03-04
Genre: Science
ISBN: 9780470399590
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This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

The Organic Chemistry of Drug Synthesis, Volume 7

The Organic Chemistry of Drug Synthesis, Volume 7
Author: Daniel Lednicer
Publisher: John Wiley & Sons
Total Pages: 288
Release: 2007-12-14
Genre: Science
ISBN: 0470180668
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The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.

Synthesis of Best-Seller Drugs

Synthesis of Best-Seller Drugs
Author: Ruben Vardanyan
Publisher: Academic Press
Total Pages: 870
Release: 2016-01-07
Genre: Medical
ISBN: 0124115241
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Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation