Decoding The Human Genome: An Overview

Decoding The Human Genome: An Overview
Author: Nicky Huys
Publisher: Nicky Huys
Total Pages: 138
Release: 2023-12-16
Genre: Science
ISBN:

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"Decoding the Human Genome: An Overview" provides a comprehensive exploration of the groundbreaking advancements in genomics and their impact on understanding the intricacies of human DNA. From the historical milestones in genome sequencing to the latest breakthroughs in personalized medicine, this book offers a clear and accessible overview of the complex world of genetics. Readers will delve into the significance of genetic variation, the role of gene expression, and the implications for addressing genetic disorders. With a focus on the potential applications in healthcare and research, this book serves as an essential guide to the fundamental principles and cutting-edge developments in decoding the human genome.

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ISBN: 0761354891

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Decoding Our DNA

Decoding Our DNA
Author: Karen Gunnison Ballen
Publisher: Twenty-First Century Books
Total Pages: 68
Release: 2012-08-01
Genre: Young Adult Nonfiction
ISBN: 1467701424

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In the mid-1980s, some geneticists proposed a daring project to sequence the human genome. That meant figuring out the exact order of the three billion chemical pairs that make up human DNA. Sequencing the human genome could help scientists understand how our bodies work and help doctors diagnose, treat, and prevent certain diseases. The Human Genome Project launched in 1990, with scientists around the world collaborating on the research. They worked slowly and methodically, trying to produce the most accurate information possible. By 1991 one of these scientists, Craig Venter, became fed up with the HGP's slow pace. He challenged the HGP to move faster and started his own company to compete with the HGP. Racing neck and neck, the two organizations reached their goal years ahead of schedule. But the challenge also led to a bitter public argument, especially over who could use the sequence and how. This book reveals how ambition, persistence, ego, greed, and principle combined—often with explosive results—in the quest to decode our DNA.

Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome
Author: National Research Council
Publisher: National Academies Press
Total Pages: 128
Release: 1988-01-01
Genre: Science
ISBN: 0309038405

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There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Introduction to Genomics

Introduction to Genomics
Author: Arthur Lesk
Publisher: Oxford University Press, USA
Total Pages: 421
Release: 2012
Genre: Medical
ISBN: 0199564353

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This book covers the latest techniques that enable us to study the genome in detail, the book explores what the genome tells us about life at the level of the molecule, the cell, and the organism

A Life Decoded

A Life Decoded
Author: J. Craig Venter
Publisher: Penguin
Total Pages: 400
Release: 2007-10-18
Genre: Biography & Autobiography
ISBN: 1101202564

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The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.

The Human Genome Project

The Human Genome Project
Author: Kevin Alexander Boon
Publisher: Enslow Publishing
Total Pages: 136
Release: 2002
Genre: Juvenile Nonfiction
ISBN:

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Discusses genes, genetics, and the legal and ethical issues involved in mapping DNA in the human body.

Cracking the Genome

Cracking the Genome
Author: Kevin Davies
Publisher: JHU Press
Total Pages: 358
Release: 2002-10
Genre: Medical
ISBN: 9780801871405

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This newly updated edition sheds light on the secrets of the sequence, highlighting the myriad ways in which genomics will impact human health for generations to come.

Recoding: Expansion of Decoding Rules Enriches Gene Expression

Recoding: Expansion of Decoding Rules Enriches Gene Expression
Author: John F. Atkins
Publisher: Springer Science & Business Media
Total Pages: 473
Release: 2010-03-10
Genre: Science
ISBN: 0387893822

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The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.

Life Script

Life Script
Author: Nicholas Wade
Publisher: Simon and Schuster
Total Pages: 209
Release: 2002-03-02
Genre: Science
ISBN: 074321739X

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With the decoding of the human genome, researchers can now read the script in which evolution has written the program for the design and operation of the human body. A new generation of medical treatments is at hand. Researchers are developing therapies so powerful that there is now no evident obstacle to the ancient goal of conquering most major diseases. Nicholas Wade has covered the sequencing of the genome, as well as other health and science stories, for The New York Times, in the course of which he has interviewed many of the principal researchers in the field. In this book he describes what the genome means for the health of present and future generations. Someday soon physicians will have access to DNA chips that, from a drop of blood, will screen a person's genes for all the diseases to which he or she may be genetically vulnerable. From full knowledge of the instruction manual of the human body, provided by the genome, pharmaceutical companies hope to develop a new generation of sophisticated drugs; one of the first genome-derived drugs is already undergoing clinical trials. Another vital tool will be regenerative medicine, a new kind of therapy in which new organs and tissues will be grown from a patient's own cells to replace those that are old or diseased. With the help of DNA chips, medical researchers will soon be able to diagnose diseases such as cancer much more precisely and to tailor specific treatments for each patient. Individualized medicine will also become an important part of the pharmaceutical world. Many drugs will be prescribed based on information from DNA chips that identify which of a range of drugs is best for each patient, as well as which drugs are likely to cause side effects. The medicine of the post-genomic era will be customized for a patient's genetic make-up, providing treatments based on a precise understanding of the mechanism of disease. Life Script describes a future in which good health, even perfect health, may become the standard for everyone -- at every age.