Catalytic Antibodies

Catalytic Antibodies
Author: Sudhir Paul
Publisher: Karger Medical and Scientific Publishers
Total Pages: 172
Release: 2000-01-01
Genre: Medical
ISBN: 3805570996

Download Catalytic Antibodies Book in PDF, Epub and Kindle

This volume addresses fundamental questions concerning the immunological genesis of the catalytic activity in antibodies, its relationship with classical antigen binding activity, and the biochemical mechanisms involved in catalysis. The contents reflect three main challenges in the field, i.e. to delineate the biological functions of catalytic antibodies in autoimmune disease; to isolate therapy-grade antibody catalysts with sufficient specificity and turnover to permit rapid removal of microbial and tumor antigens; and to develop immunogens that recruit immature catalyst-producing B cells into the clonal selection pathway and induce adaptive improvements of the catalytic function. Well-edited and up-to-date, this book reviews the current knowledge in the field and explores ways by which natural and engineered catalytic activities can be harnessed for medical applications. It should therefore be of special interest to immunologists, biochemists, biotechnologists, rheumatologists and pathologists.

Catalytic Antibodies

Catalytic Antibodies
Author: Ehud Keinan
Publisher: John Wiley & Sons
Total Pages: 616
Release: 2006-03-06
Genre: Science
ISBN: 3527605053

Download Catalytic Antibodies Book in PDF, Epub and Kindle

Exploiting the inherent combinatorial mechanism in the biosynthesis of antibodies, an almost limitless variety of biocatalysts may be generated. Catalytic antibodies are capable of performing almost any type of reaction with high selectivity and stereospecificity. Here, the pioneers in the use of catalytic antibodies review the entire scope of this interdisciplinary field, covering such topics as: * theoretical aspects of structure, mechanism and kinetics * practical considerations, from immunization techniques to screening methods * in vitro evolution and other modern approaches * applications from organic synthesis to medical uses. Backed by the leading authorities in antibody catalysis, this is the first book to provide such comprehensive coverage and constitutes a prime reference for biochemists, organic chemists, biotechnologists and biomedical researchers.

Designing Antibodies

Designing Antibodies
Author: Ruth Mayforth
Publisher: Academic Press
Total Pages: 217
Release: 2012-12-02
Genre: Medical
ISBN: 0323160026

Download Designing Antibodies Book in PDF, Epub and Kindle

Designing Antibodies provides a compilation of research in the design of antibodies. It describes the techniques used in antibody design, the kinds of antibodies generated through modern techniques, and their applications in medicine and science. The book begins with an overview of the humoral immune system and of antibody structure, function, and biosynthesis, which sets the stage for the subsequent discussions of developments in antibody technology. The remaining chapters discuss the making of monoclonal antibodies; the design of antibodies for human therapy; the connection of antibodies (either chemically or genetically) to other potentially therapeutic effector molecules such as toxins, enzymes, or even an antibody of another specificity; idiotypes and anti-idiotypic antibodies; and the ability of antibodies to functionally mimic enzymes and mediate catalysis. It is hoped that, in addition to illustrating the progress of research in antibody design, the various creative and innovative approaches reviewed in this book will be modified or will stimulate new ideas that will spur the research and application of designer antibodies.

Catalytic Antibodies

Catalytic Antibodies
Author:
Publisher:
Total Pages: 259
Release: 1991
Genre:
ISBN:

Download Catalytic Antibodies Book in PDF, Epub and Kindle

Catalytic Antibodies

Catalytic Antibodies
Author: Derek J. Chadwick
Publisher: John Wiley & Sons
Total Pages: 270
Release: 2008-04-30
Genre: Science
ISBN: 0470514116

Download Catalytic Antibodies Book in PDF, Epub and Kindle

Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.

Molecularly Imprinted Catalysts

Molecularly Imprinted Catalysts
Author: Songjun Li
Publisher: Elsevier
Total Pages: 312
Release: 2015-09-30
Genre: Technology & Engineering
ISBN: 012801444X

Download Molecularly Imprinted Catalysts Book in PDF, Epub and Kindle

Molecularly Imprinted Catalysts: Principle, Synthesis, and Applications is the first book of its kind to provide an in-depth overview of molecularly imprinted catalysts and selective catalysis, including technical details, principles of selective catalysis, preparation processes, the catalytically active polymers themselves, and important progress made in this field. It serves as an important reference for scientists, students, and researchers who are working in the areas of molecular imprinting, catalysis, molecular recognition, materials science, biotechnology, and nanotechnology. Comprising a diverse group of experts from prestigious universities and industries across the world, the contributors to this book provide access to the latest knowledge and eye-catching achievements in the field, and an understanding of what progress has been made and to what extent it is being advanced in industry. The first book in the field on molecularly imprinted catalysts (MIPs) Provides a systematic background to selective catalysis, especially the basic concepts and key principles of the different MIP-based catalysts Features state-of-the art presentation of preparation methods and applications of MIPs Written by scientists from prestigious universities and industries across the world, and edited by veteran researchers in molecular imprinting and selective catalysis

Wiley Encyclopedia of Chemical Biology, Volume 1

Wiley Encyclopedia of Chemical Biology, Volume 1
Author: Tadhg P. Begley
Publisher: Wiley-Blackwell
Total Pages: 756
Release: 2009
Genre: Science
ISBN:

Download Wiley Encyclopedia of Chemical Biology, Volume 1 Book in PDF, Epub and Kindle

The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.

Catalytic Antibodies

Catalytic Antibodies
Author: Jeffrey William Jacobs
Publisher:
Total Pages: 276
Release: 1990
Genre: Haptens
ISBN:

Download Catalytic Antibodies Book in PDF, Epub and Kindle

Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

Download Molecular Biology of The Cell Book in PDF, Epub and Kindle

Catalytic Antibodies

Catalytic Antibodies
Author: David Young Jackson
Publisher:
Total Pages: 568
Release: 1992
Genre:
ISBN:

Download Catalytic Antibodies Book in PDF, Epub and Kindle