Chiral Separations by Capillary Electrophoresis

Chiral Separations by Capillary Electrophoresis
Author: Ann Van Eeckhaut
Publisher: CRC Press
Total Pages: 546
Release: 2009-11-11
Genre: Medical
ISBN: 1420069349

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Covers the Fundamentals of Chiral Separation, Available Chiral Selectors, and Numerous Applications of Chiral Separation by Capillary ElectrophoresisSince the 1980s, modern analytical tools have enabled capillary electrophoresis to become a standard part of the chemist's toolkit. With contributions from international experts, Chiral Separations by

Capillary Electrophoresis in Chiral Analysis

Capillary Electrophoresis in Chiral Analysis
Author: Bezhan Chankvetadze
Publisher: John Wiley & Sons
Total Pages: 586
Release: 1997-12-29
Genre: Science
ISBN: 9780471974154

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Das weltweite Interesse an der Trennung von Enantiomeren, Spiegelbildern ein und derselben chemischen Verbindung, nimmt zu, da diese Formen beispielsweise verschiedene physiologische Wirkungen hervorrufen können. Eine hochaktuelle Technik der Stofftrennung in diesem Zusammenhang ist die Kapillarelektrophorese, die hier von den theoretischen Grundlagen bis hin zu analytischen Details und Anbieterlisten ausführlich beschrieben wird.

Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis

Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis
Author: Peter Mikuš
Publisher: BoD – Books on Demand
Total Pages: 211
Release: 2012-08-29
Genre: Medical
ISBN: 9535106570

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The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques.

Chiral Pollutants

Chiral Pollutants
Author: Imran Ali
Publisher: John Wiley & Sons
Total Pages: 368
Release: 2005-07-15
Genre: Science
ISBN: 0470867817

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Today, among the various chiral discrimination methods, chromatography and capillary electrophoresis techniques have become powerful tools in environmental analysis. Therefore, there is a need to describe the art of the determination of the chiral pollutants in the environmental matrices. This book provides the complete information on the types of the chiral pollutants, their toxicities and methods of determination by chromatography and capillary electrophoresis.

The Separation of Enantiomers by Capillary Electrophoresis

The Separation of Enantiomers by Capillary Electrophoresis
Author: Stephen Wren
Publisher: Springer Science & Business Media
Total Pages: 96
Release: 2013-04-17
Genre: Technology & Engineering
ISBN: 3322831418

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This book gives a comprehensive overview on the principles of physical and mathematical modelling of enantiomer separation by CE. Method development strategies are shown and cyclodextrins as a popular group of chiral selectors as well as some other selectors used as buffer additives for enantiomer separation in free solution are described.

Capillary Electrophoresis in Biotechnology and Environmental Analysis

Capillary Electrophoresis in Biotechnology and Environmental Analysis
Author: Hasan Parvez
Publisher: CRC Press
Total Pages: 495
Release: 2023-01-06
Genre: Science
ISBN: 1466563699

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This text aims to evaluate the actual impact of high-performance capillary electrophoresis on analytical biotechnology and environmental analysis. The first part of the book presents a survey of present innovations in instrument design and different methods of pre-concentration techniques in order to obtain increased separations at higher sensitivities. The second part contains articles on applications of HPCE to protein and peptide analysis. In the third part, applications of HPCE in the investigation of drug abuse and drug interactions are presented. The last two parts of the book deal with the use of HPCE at low-UV wavelengths and negative-UV absorption. The book should be of interest to those working in HPCE research and applications.

Capillary Electrophoresis

Capillary Electrophoresis
Author: Suvardhan Kanchi
Publisher: CRC Press
Total Pages: 396
Release: 2017-08-21
Genre: Medical
ISBN: 1351846736

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Capillary electrophoresis (CE) has become an established method with widespread recognition as an analytical technique of choice in numerous analytical laboratories, including industrial and academic sectors. Pharmaceutical and biochemical research and quality control are the most important CE applications. This book provides a comparative assessment of related techniques on mode selection, method development, detection, and quantitative analysis and estimation of pharmacokinetic parameters and broadens the understanding of modern CE applications, developments, and prospects. It introduces the fundamentals of CE and clearly outlines the procedures used to mitigate several barriers, such as detection limits, signal detection, changing capillary environment, resolution separation of analytes, and hyphenation of mass spectrometry with CE, for a range of analytical problems. Each chapter outlines a specific electrophoretic variant with detailed instructions and some standard operating procedures. In this respect, the book meets its desired goal of rendering assistance to lovers of electrophoresis.

Analysis and Detection by Capillary Electrophoresis

Analysis and Detection by Capillary Electrophoresis
Author: Maria Luisa Marina
Publisher: Elsevier
Total Pages: 797
Release: 2005-09-06
Genre: Science
ISBN: 0080456235

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Capillary Electrophoresis (CE) is a powerful analytical technique used to separate compounds and is increasingly being used in routine analytical laboratories. Analysis and Detection by Capillary Electrophoresis presents developments enabling the enhancement of the detection sensitivity in CE, including the different strategies used to achieve sensitivity requirements. It describes techniques allowing sample preconcentration and sensitive continuous detection systems and looks at recent developments such as chiral analysis in CE and electrochemical detection in microchips. UV-Vis absorbance detection, as the most widely used detection system in CE, is also presented. Analysis and Detection by Capillary Electrophoresis delves into the practical approaches used in the field and will greatly benefit analytical chemists, as well as students, teachers, technical analysts, scientists and researchers involved in capillary electrophoresis. * An overview of practical approaches employed in capillary electrophoresis, including the fundamentals, instrumentation, and applications of continuous detections systems employed in capillary electrophoresis * Covers aspects of capillary electrophoresis that have never previously been covered * Written by leading experts in the field

Chiral Separations

Chiral Separations
Author: Gerald Gübitz
Publisher: Springer Science & Business Media
Total Pages: 427
Release: 2008-02-02
Genre: Science
ISBN: 1592596487

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Prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotographic, gas chromatographic, supercritical fluid chromatographic as well as recent electrochromotographic techniques.