Biomolecular Nmr Spectroscopy
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| Author | : Andrew J. Dingley |
| Publisher | : IOS Press |
| Total Pages | : 488 |
| Release | : 2011 |
| Genre | : Medical |
| ISBN | : 1607506947 |
Download Biomolecular NMR Spectroscopy Book in PDF, Epub and Kindle
Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful technique for characterization of biomolecular structures at atomic resolution in the solution state. This timely book, entitled "Biomolecular NMR Spectroscopy," focuses on the latest state-of-the-art NMR techniques for characterization of biological macromolecules in the solid and solution state. The editors, Dr. Andrew Dingley (University of Auckland, New Zealand) and Dr. Steven Pascal (Massey University, New Zealand) have organized the book into four sections, covering the following topics: sample preparation, structure and dynamics of proteins, structure and dynamics of nucleic acids and protein-nucleic acid complexes, and rapid and hybrid techniques--
| Author | : John L. Markley |
| Publisher | : Oxford University Press |
| Total Pages | : 375 |
| Release | : 1997-01-30 |
| Genre | : Science |
| ISBN | : 0195357426 |
Download Biological NMR Spectroscopy Book in PDF, Epub and Kindle
This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.
| Author | : Jeremy N. S. Evans |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 444 |
| Release | : 1995 |
| Genre | : Science |
| ISBN | : 9780198547662 |
Download Biomolecular NMR Spectroscopy Book in PDF, Epub and Kindle
The technique of nuclear magnetic resonance (NMR) spectroscopy is an important tool in biochemistry and biophysics for the understanding of the structure and ultimately, the function of biomolecules. This textbook explains the salient features of biological NMR spectroscopy to undergraduates and postgraduates taking courses in NMR, biological NMR, physical biochemistry, and biophysics. Unlike other books in the general field of NMR (except the advanced treatises), the approach here is tointroduce and make use of quantum mechanical product operators as well as the classical vector method of explaining the bewildering array of pulse sequences available today. The book covers two- dimensional, three- dimensional, and four- dimensional NMR and their application to protein and DNA structure determination. A unique feature is the coverage of the biological aspects of solid- state NMR spectroscopy. The author provides many selected examples from the research literature, illustratingthe applications of NMR spectroscopy to biological proteins.
| Author | : Gordon S. Rule |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 543 |
| Release | : 2006-02-16 |
| Genre | : Science |
| ISBN | : 1402035004 |
Download Fundamentals of Protein NMR Spectroscopy Book in PDF, Epub and Kindle
NMR spectroscopy has proven to be a powerful technique to study the structure and dynamics of biological macromolecules. Fundamentals of Protein NMR Spectroscopy is a comprehensive textbook that guides the reader from a basic understanding of the phenomenological properties of magnetic resonance to the application and interpretation of modern multi-dimensional NMR experiments on 15N/13C-labeled proteins. Beginning with elementary quantum mechanics, a set of practical rules is presented and used to describe many commonly employed multi-dimensional, multi-nuclear NMR pulse sequences. A modular analysis of NMR pulse sequence building blocks also provides a basis for understanding and developing novel pulse programs. This text not only covers topics from chemical shift assignment to protein structure refinement, as well as the analysis of protein dynamics and chemical kinetics, but also provides a practical guide to many aspects of modern spectrometer hardware, sample preparation, experimental set-up, and data processing. End of chapter exercises are included to emphasize important concepts. Fundamentals of Protein NMR Spectroscopy not only offer students a systematic, in-depth, understanding of modern NMR spectroscopy and its application to biomolecular systems, but will also be a useful reference for the experienced investigator.
| Author | : Marius Clore |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 362 |
| Release | : 2012 |
| Genre | : Science |
| ISBN | : 1849731209 |
Download Recent Developments in Biomolecular NMR Book in PDF, Epub and Kindle
This text draws together experts in the field to discuss advances in nuclear magnetic resonance methods that have occurred or had an impact on the biomolecular field in the last few years.
| Author | : K.V.R. Chary |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 552 |
| Release | : 2008-04-01 |
| Genre | : Science |
| ISBN | : 1402066805 |
Download NMR in Biological Systems Book in PDF, Epub and Kindle
During teaching NMR to students and researchers, we felt the need for a text-book which can cover modern trends in the application of NMR to biological systems. This book covers the entire area of NMR in Biological Sciences (Biomolecules, cells and tissues, animals, plants and drug design). As well as being useful to researchers, this is an excellent book for teaching a course on NMR in Biological Systems.
| Author | : Michaeleen Doucleff |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 166 |
| Release | : 2011-01-03 |
| Genre | : Science |
| ISBN | : 3642162517 |
Download Pocket Guide to Biomolecular NMR Book in PDF, Epub and Kindle
Steering clear of quantum mechanics and product operators, "Pocket Guide to Biomolecular NMR" uses intuitive, concrete analogies to explain the theory required to understand NMR studies on the structure and dynamics of biological macromolecules. For example, instead of explaining nuclear spin with angular momentum equations or Hamiltonians, the books describes nuclei as "bells" in a choir, ringing at specific frequencies depending on the atom type and their surrounding electromagnetic environment.This simple bell analogy, which is employed throughout the book, has never been used to explain NMR and makes it surprisingly easy to learn complex, bewildering NMR concepts, such as dipole-dipole coupling and CPMG pulse sequences. Other topics covered include the basics of multi-dimensional NMR, relaxation theory, and Model Free analysis. The small size and fast pace of “Pocket Guide to Biomolecular NMR” makes the book a perfect companion to traditional biophysics and biochemistry textbooks, but the book's unique perspective will provide even seasoned spectroscopists with new insights and handy “thought” short-cuts.
| Author | : Yutaka Ito |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 322 |
| Release | : 2019-12-13 |
| Genre | : Science |
| ISBN | : 1788012178 |
Download In-cell NMR Spectroscopy Book in PDF, Epub and Kindle
In-cell NMR spectroscopy is a relatively new field. Despite its short history, recent in-cell NMR-related publications in major journals indicate that this method is receiving significant general attention. This book provides the first informative work specifically focused on in-cell NMR. It details the historical background of in-cell NMR, host cells for in-cell NMR studies, methods for in-cell biological techniques and NMR spectroscopy, applications, and future perspectives. Researchers in biochemistry, biophysics, molecular biology, cell biology, structural biology as well as NMR analysts interested in biological applications will all find this book valuable reading.
| Author | : S.K. Sarkar |
| Publisher | : Elsevier |
| Total Pages | : 407 |
| Release | : 1996-12-04 |
| Genre | : Science |
| ISBN | : 0080537596 |
Download NMR Spectroscopy and its Application to Biomedical Research Book in PDF, Epub and Kindle
NMR has become the most diverse spectroscopic tool available to date in biomedical research. It is now routinely used to study biomolecular structure and dynamics particularly as a result of recent developments of a cascade of highly sophisticated multidimensional NMR pulse sequences, and of advances in genetic engineering to produce biomolecules, uniformly or selectively enriched with 13C, 15N and 2H. Features of this book: • Provides an up-to-date treatment of NMR techniques and their application to problems of biomedical interest • Most refined multidimensional pulse sequences including the basic aspects are covered by leading NMR spectroscopists. The book will be useful to NMR spectroscopists, biochemists, and to molecular biologists interested in the use of NMR techniques for solving biological problems.
| Author | : Hanudatta S. Atreya |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 219 |
| Release | : 2012-10-18 |
| Genre | : Medical |
| ISBN | : 9400749546 |
Download Isotope labeling in Biomolecular NMR Book in PDF, Epub and Kindle
NMR spectroscopy has undergone a revolution in recent years with the advent of several new methods overcoming the problems of sensitivity and resolution. Recent developments in biotechnology have made it easier and economical to introduce 13C, 15N and 2H into proteins and nucleic acids. At the same time, there has been an explosion in the number of NMR experiments that utilize such isotope labeled samples. Thus, a combination of isotopic labeling and multidimensional, multinuclear NMR has opened up new avenues for structural studies of proteins, nucleic acids and their complexes. This book will focus on recent developments in isotope labeling methods for structural studies of small molecules, peptides, proteins and nucleic acids. The aim of the book is to serve as a compendium of isotope labeling for the biomolecular NMR community providing comprehensive coverage of the existing methods and latest developments along with protocols and practical hints on the various experimental aspects. The book will cover a wide range of topics in isotope labeling under one title including emerging areas of metabolonomics and solid state NMR.
