Biomimetic Organic Synthesis

Biomimetic Organic Synthesis
Author: Erwan Poupon
Publisher: John Wiley & Sons
Total Pages: 1024
Release: 2011-05-09
Genre: Science
ISBN: 3527634762

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In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of complex natural products is laid out, backed by abundant practical examples from the authors' own work as well as from the published literature. Volume 1 describes the biomimetic synthesis of alkaloids. Volume 2 covers terpenes, polyketides, and polyphenols. A discussion of the current challenges and frontiers in biomimetic synthesis concludes this comprehensive handbook. Key features: Biomimetic Strategies have become an every-day tool not only for chemists but also for biologists. The synthetic applications are overwhelming, making this comprehensive 2 volume work a must-have for everyone working in the field. Unifying both synthetic and biosynthetic aspects, this book covers everything from organocatalysis and natural product synthesis to synthetic biology and even green chemistry.

Biomimetic organic synthesis. 1. Alkaloids

Biomimetic organic synthesis. 1. Alkaloids
Author: Erwan Poupon
Publisher:
Total Pages: 394
Release: 2011
Genre: Biomimetics
ISBN:

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Important key definitions and general concepts are provided in a tutorial way. Natural product synthesis are classified according to main biosynthetic pathways (e.g. terpenes, alkaloids, polyketides). A focus is on biomimetic efforts towrds the total synthesis of natural products.

Alkaloids

Alkaloids
Author: Erwan Poupon
Publisher:
Total Pages: 394
Release: 2011
Genre:
ISBN:

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Modern Inorganic Synthetic Chemistry

Modern Inorganic Synthetic Chemistry
Author: Ruren Xu
Publisher: Elsevier
Total Pages: 810
Release: 2017-02-11
Genre: Science
ISBN: 0444635955

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Modern Inorganic Synthetic Chemistry, Second Edition captures, in five distinct sections, the latest advancements in inorganic synthetic chemistry, providing materials chemists, chemical engineers, and materials scientists with a valuable reference source to help them advance their research efforts and achieve breakthroughs. Section one includes six chapters centering on synthetic chemistry under specific conditions, such as high-temperature, low-temperature and cryogenic, hydrothermal and solvothermal, high-pressure, photochemical and fusion conditions. Section two focuses on the synthesis and related chemistry problems of highly distinct categories of inorganic compounds, including superheavy elements, coordination compounds and coordination polymers, cluster compounds, organometallic compounds, inorganic polymers, and nonstoichiometric compounds. Section three elaborates on the synthetic chemistry of five important classes of inorganic functional materials, namely, ordered porous materials, carbon materials, advanced ceramic materials, host-guest materials, and hierarchically structured materials. Section four consists of four chapters where the synthesis of functional inorganic aggregates is discussed, giving special attention to the growth of single crystals, assembly of nanomaterials, and preparation of amorphous materials and membranes. The new edition’s biggest highlight is Section five where the frontier in inorganic synthetic chemistry is reviewed by focusing on biomimetic synthesis and rationally designed synthesis. Focuses on the chemistry of inorganic synthesis, assembly, and organization of wide-ranging inorganic systems Covers all major methodologies of inorganic synthesis Provides state-of-the-art synthetic methods Includes real examples in the organization of complex inorganic functional materials Contains more than 4000 references that are all highly reflective of the latest advancement in inorganic synthetic chemistry Presents a comprehensive coverage of the key issues involved in modern inorganic synthetic chemistry as written by experts in the field

The Isoquinoline Alkaloids

The Isoquinoline Alkaloids
Author: K. W. Bentley
Publisher: Elsevier
Total Pages: 273
Release: 2014-04-24
Genre: Science
ISBN: 1483152235

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The Isoquinoline Alkaloids: A Course in Organic Chemistry is a description of the chemical structures of alkaloids. The book discusses the processes for degradation of isoquinoline alkaloids to recognizable compounds such as oxidation and exhaustive methylation. The associated processes in removing the nitrogen atom are also explained. The commonly used Hofmann process and the interpretation of its result are evaluated in the degradation of alkaloids. The cactus ""pellote"" used by Mexican Indians to induce hallucinatory experiences is examined. The active ingredient is identified as mescaline; its composition is analyzed to contain one primary amino and three methoxyl groups. The different syntheses made to duplicate mescaline are described. The structures of morphine, codeine, and thebain, which are all alkaloids of opium, are also analyzed. Another example of a principal alkaloid found in a plant is emetine found in the root of the ipecac. The pharmacological bases of emetine are isolated and noted as emetamine, cephaeline, psychotrine, and O-methylpsychotrine. The text also traces many other structural relationships within the subgroups of the isoquinoline alkaloids. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology will find this book informative.

Alkaloids

Alkaloids
Author: Tadeusz Aniszewski
Publisher: Elsevier
Total Pages: 494
Release: 2015-04-25
Genre: Science
ISBN: 0444594620

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Alkaloids - Secrets of Life: Alkaloid Chemistry, Biological Significance, Applications and Ecological Role, Second Edition provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids, considering an organic chemistry approach to alkaloids using biological and ecological explanation. The book approaches several questions and unresearched areas that persist in this field of research. It provides a beneficial text for academics, professionals or anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices, a listing of alkaloids, and plants containing alkaloids are all included, as are basic protocols of alkaloid analysis. Presents the ecological role of alkaloids in nature and ecosystems interdisciplinary Examines alkaloids from chemistry, biology and ecology viewpoints A single handy reference volume comprehensively reviews the origin of alkaloids and their biological uses Over 80% new information, including new chapters on the ecological role of alkaloids in nature and ecosystems and extraction of alkaloids

Modern Alkaloids

Modern Alkaloids
Author: Ernesto Fattorusso
Publisher: John Wiley & Sons
Total Pages: 689
Release: 2008-01-08
Genre: Science
ISBN: 3527621083

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This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis. A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry.

Alkaloid Synthesis

Alkaloid Synthesis
Author: Hans-Joachim Knoelker
Publisher: Springer Science & Business Media
Total Pages: 268
Release: 2012-01-13
Genre: Science
ISBN: 3642255280

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Lycopodium Alkaloids: Isolation and Asymmetric Synthesis, by Mariko Kitajima and Hiromitsu Takayama.- Synthesis of Morphine Alkaloids and Derivatives, by Uwe Rinner and Tomas Hudlicky.- Indole Prenylation in Alkaloid Synthesis, by Thomas Lindel, Nils Marsch and Santosh Kumar Adla.- Marine Pyrroloiminoquinone Alkaloids, by Yasuyuki Kita and Hiromichi Fujioka.- Synthetic Studies on Amaryllidaceae and Other Terrestrially Derived Alkaloids, by Martin G. Banwell, Nadia Yuqian Gao, Brett D. Schwartz and Lorenzo V. White.- Synthesis of Pyrrole and Carbazole Alkaloids, by Ingmar Bauer and Hans-Joachim Knölker.-

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author: Gopal Sirasani
Publisher: Elsevier Inc. Chapters
Total Pages: 39
Release: 2013-07-29
Genre: Science
ISBN: 0128056045

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Described herein is an account of my laboratory’s entry into the magnificent field of complex alkaloid total synthesis, spanning the development of novel methods for quickly assembling polycyclic frameworks through the total synthesis of various members of the Strychnos alkaloids. A discussion of the prior art related to our approach to these alkaloids in addition to strategic decisions and reasoning made en route to targets akuammicine ( 1 ), strychnine ( 2 ), and leuconicines A ( 3 ) and B ( 4 ) is carefully detailed. Finally, we present the retrosynthetic analyses of the aforementioned targets and respective total syntheses thereof (including asymmetric variants).