Computer-Aided Tissue Engineering

Computer-Aided Tissue Engineering
Author: Michael A.K. Liebschner
Publisher: Humana Press
Total Pages: 0
Release: 2012-06-14
Genre: Science
ISBN: 9781617797637

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The recent revolution in the biological sciences and bioengineering, along with the advancements of modern design and manufacturing, biomaterials, biology, and biomedicine, have brought about the new field of computer-aided tissue engineering. Advances in this fascinating new area of study encompass broad applications in large-scale tissue engineering fabrication, artificial organs, orthopaedic implants, and biological chips. Computer-Aided Tissue Engineering highlights the interdisciplinary nature of this topic and reviews the current state of computer-aided three-dimensional tissue modeling, tissue classification, and tissue fabrication and implantation. Particular focus is placed on rapid prototyping and direct digital fabrication for cell and organs, construction of tissue analogs, and precursors to 3D tissue scaffolds. Written for the highly successful Methods in Molecular BiologyTM series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Current and practical, Computer-Aided Tissue Engineering provides a coherent framework for researchers interested in these vital technologies and for clinicians who plan to implement them.

Scaffolds for Tissue Engineering

Scaffolds for Tissue Engineering
Author: Claudio Migliaresi
Publisher: CRC Press
Total Pages: 671
Release: 2014-06-10
Genre: Medical
ISBN: 9814463213

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Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are deri

Biofabrication

Biofabrication
Author: Joydip Kundu
Publisher: Elsevier Inc. Chapters
Total Pages: 38
Release: 2013-03-18
Genre: Medical
ISBN: 0128090499

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Biomaterials have advanced from merely interacting with the body to controlling biological processes toward the goal of tissue regeneration. In order to reconstitute a new tissue or repair a damaged/diseased tissue, three components are critical for regenerative medicine or tissue engineering: cells, biomaterials as scaffold substrates, and growth factors. Thus, the design and selection of materials and the methods used for scaffold fabrication play a very important role in tissue engineering and regenerative medicine. Recent developments in biofabrication strategies have created enormous possibilities for the construction of biomimetic 3D scaffolds, where well-defined architectures can be generated with suitable surface chemistry using appropriate materials. This chapter summarizes the materials used for the fabrication of scaffolds, the different types of scaffold manufacturing processes, and the basics of the various tissue-specific scaffolds used in regenerative medicine.

Computer-Aided Tissue Engineering

Computer-Aided Tissue Engineering
Author: Alberto Rainer
Publisher: Humana
Total Pages: 188
Release: 2021-09-09
Genre: Science
ISBN: 9781071606131

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This volume details protocols encompassing different aspects of computer aided design and manufacturing of 3D scaffolds and biofabricated constructs for tissue engineering applications. Chapters are divided into four parts covering optimization of scaffold architectures for computer aided tissue engineering, synthetic routes to biomaterials compatible, technological platforms and manufacturing processes, and relevant applicative scenarios. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computer-Aided Tissue Engineering: Methods and Protocols aims to be useful for new and experienced laboratory researchers working on different aspects of corneal regeneration.

Engineered Biomimicry

Engineered Biomimicry
Author: Princeton Carter
Publisher: Elsevier Inc. Chapters
Total Pages: 59
Release: 2013-05-24
Genre: Medical
ISBN: 0128072652

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The fabrication of three-dimensional (3D) scaffold architectures that closely approximate or effectively mimic native tissue extracellular matrix (ECM) is essential for regenerative success. In tissue engineering, native differentiable cells are incorporated into 3D scaffolds along with growth factors and other proteins. Materials used for the 3D scaffold construction must be biocompatible and bioresorbable to minimize adverse reactions during tissue regeneration. A 3D architecture is created by utilizing materials with specific surface properties, porosity, mechanical strength, etc., to improve desired cell activity and enhance tissue growth. Ideal 3D scaffolds should also not only have hierarchical macroporous structures comparable to those of living tissue, but they should also have surface features on the nanometer scale to improve cell adhesion and accelerate cell in growth.

Tissue Engineering

Tissue Engineering
Author: Paulo Rui Fernandes
Publisher: Springer Science & Business Media
Total Pages: 191
Release: 2013-07-31
Genre: Technology & Engineering
ISBN: 9400770731

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This book describes the state of the art on computational modeling and fabrication in Tissue Engineering. It is inspired by the ECCOMAS thematic conference, the European Committee on Computational Methods in Applied Sciences, on Tissue Engineering, held in Lisbon, Portugal, June 2-4, 2011. Tissue Engineering is a multidisciplinary field involving scientists from different fields. The development of mathematical methods is quite relevant to understand cell biology and human tissues as well to model, design and fabricate optimized and smart scaffolds. Emphasis is put on mathematical and computational modeling for scaffold design and fabrication. This particular area of tissue engineering, whose goal is to obtain substitutes for hard tissues such as bone and cartilage, is growing in importance.

Extrusion Bioprinting of Scaffolds for Tissue Engineering Applications

Extrusion Bioprinting of Scaffolds for Tissue Engineering Applications
Author: Daniel X. B. Chen
Publisher: Springer
Total Pages: 171
Release: 2018-12-13
Genre: Technology & Engineering
ISBN: 3030034607

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This book introduces readers to the theory and practice of extrusion bio-printing of scaffolds for tissue engineering applications. The author emphasizes the fundamentals and practical applications of extrusion bio-printing to scaffold fabrication, in a manner particularly suitable for those who wish to master the subject matter and apply it to real tissue engineering applications. Readers will learn to design, fabricate, and characterize tissue scaffolds to be created by means of extrusion bio-printing technology.