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| Release | : 1998 |
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| Author | : Walter Maurel |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 188 |
| Release | : 2013-11-22 |
| Genre | : Computers |
| ISBN | : 3662035898 |
An overview of biomechanical modeling of human soft tissue using nonlinear theoretical mechanics and incremental finite element methods, useful for computer simulation of the human musculoskeletal system.
| Author | : Yohan Payan |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 392 |
| Release | : 2012-04-27 |
| Genre | : Technology & Engineering |
| ISBN | : 3642290140 |
This volume focuses on the biomechanical modeling of biological tissues in the context of Computer Assisted Surgery (CAS). More specifically, deformable soft tissues are addressed since they are the subject of the most recent developments in this field. The pioneering works on this CAS topic date from the 1980's, with applications in orthopaedics and biomechanical models of bones. More recently, however, biomechanical models of soft tissues have been proposed since most of the human body is made of soft organs that can be deformed by the surgical gesture. Such models are much more complicated to handle since the tissues can be subject to large deformations (non-linear geometrical framework) as well as complex stress/strain relationships (non-linear mechanical framework). Part 1 of the volume presents biomechanical models that have been developed in a CAS context and used during surgery. This is particularly new since most of the soft tissues models already proposed concern Computer Assisted Planning, with a pre-operative use of the models. Then, the volume addresses the two key issues raised for an intra-operative use of soft tissues models, namely (Part 2) “how to estimate the in vivo mechanical behavior of the tissues?” (i.e. what are the values of the mechanical parameters that can deliver realistic patient-specific behavior?) and (Part 3) “how to build a modeling platform that provides generic real-time (or at least interactive-time) numerical simulations?”
| Author | : Gerhard A. Holzapfel |
| Publisher | : Springer |
| Total Pages | : 319 |
| Release | : 2016-09-14 |
| Genre | : Technology & Engineering |
| ISBN | : 3319414755 |
The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
| Author | : Josef Málek |
| Publisher | : Springer Nature |
| Total Pages | : 281 |
| Release | : 2022-01-21 |
| Genre | : Mathematics |
| ISBN | : 3030880842 |
The investigation of the role of mechanical and mechano-chemical interactions in cellular processes and tissue development is a rapidly growing research field in the life sciences and in biomedical engineering. Quantitative understanding of this important area in the study of biological systems requires the development of adequate mathematical models for the simulation of the evolution of these systems in space and time. Since expertise in various fields is necessary, this calls for a multidisciplinary approach. This edited volume connects basic physical, biological, and physiological concepts to methods for the mathematical modeling of various materials by pursuing a multiscale approach, from subcellular to organ and system level. Written by active researchers, each chapter provides a detailed introduction to a given field, illustrates various approaches to creating models, and explores recent advances and future research perspectives. Topics covered include molecular dynamics simulations of lipid membranes, phenomenological continuum mechanics of tissue growth, and translational cardiovascular modeling. Modeling Biomaterials will be a valuable resource for both non-specialists and experienced researchers from various domains of science, such as applied mathematics, biophysics, computational physiology, and medicine.
| Author | : Adil Al Mayah |
| Publisher | : CRC Press |
| Total Pages | : 138 |
| Release | : 2018-02-21 |
| Genre | : Medical |
| ISBN | : 1351135813 |
The emerging paradigm of incorporating images and biomechanical properties of soft tissues has proven to be an integral part of the advancement of several medical applications, including image guided radiotherapy and surgery, brachytherapy, and diagnostics. This expansion has resulted in a growing community of medical, science, and engineering professionals applying mechanical principles to address medical concerns. This book is tailored to cover a range of mechanical principles, properties, and applications of soft tissues that have previously been addressed in various journals and "anatomical site-specific" books. Biomechanics of Soft Tissues follows a different approach by offering a simplified overview of widely used mechanical models and measuring techniques of soft tissue parameters. This is followed by an investigation of different medical applications, including: biomechanical aspects of cancerous tumor progressions, radiotherapy treatment, and image guided ultrasound guided interventions. Written by leading scholars and professionals in the field, Biomechanics of Soft Tissues combines engineering and medical expertise, thereby producing an excellent source of information for professionals interested in the theoretical and technological advancements related to soft tissues. The book provides medical professionals with an insight on various modeling approaches, testing techniques, and mechanical characteristics that are frequently used by engineers. Conversely, the presented medical applications provide engineers with a glimpse of amazing medical practices and encourage them to expand their roles in the medical field. Provides a simplified overview of mechanics of soft tissues. Highlights different techniques to measure tissues properties for engineering and medical applications. Contains novel ideas to address roles of mechanics in disease progression and treatment. Presents innovative applications of biomechanics in medical procedures.
| Author | : Grand R. Joldes |
| Publisher | : Springer |
| Total Pages | : 212 |
| Release | : 2016-06-15 |
| Genre | : Technology & Engineering |
| ISBN | : 3319283294 |
The Computational Biomechanics for Medicine titles provide an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements. This volume comprises eighteen of the newest approaches and applications of computational biomechanics, from researchers in Australia, New Zealand, USA, UK, Switzerland, Scotland, France and Russia. Some of the interesting topics discussed are: tailored computational models; traumatic brain injury; soft-tissue mechanics; medical image analysis; and clinically-relevant simulations. One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences, and medicine. We hope the research presented within this book series will contribute to overcoming this grand challenge.
| Author | : Suvranu De |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 580 |
| Release | : 2010-03-10 |
| Genre | : Technology & Engineering |
| ISBN | : 9048135753 |
Availability of advanced computational technology has fundamentally altered the investigative paradigm in the field of biomechanics. Armed with sophisticated computational tools, researchers are seeking answers to fundamental questions by exploring complex biomechanical phenomena at the molecular, cellular, tissue and organ levels. The computational armamentarium includes such diverse tools as the ab initio quantum mechanical and molecular dynamics methods at the atomistic scales and the finite element, boundary element, meshfree as well as immersed boundary and lattice-Boltzmann methods at the continuum scales. Multiscale methods that link various scales are also being developed. While most applications require forward analysis, e.g., finding deformations and stresses as a result of loading, others involve determination of constitutive parameters based on tissue imaging and inverse analysis. This book provides a glimpse of the diverse and important roles that modern computational technology is playing in various areas of biomechanics including biofluids and mass transfer, cardiovascular mechanics, musculoskeletal mechanics, soft tissue mechanics, and biomolecular mechanics.
| Author | : Francisco Chinesta |
| Publisher | : Elsevier |
| Total Pages | : 494 |
| Release | : 2023-05-25 |
| Genre | : Technology & Engineering |
| ISBN | : 0323915760 |
Reduced Order Models for the Biomechanics of Living Organs, a new volume in the Biomechanics of Living Organisms series, provides a comprehensive overview of the state-of-the-art in biomechanical computations using reduced order models, along with a deeper understanding of the associated reduction algorithms that will face students, researchers, clinicians and industrial partners in the future. The book gathers perspectives from key opinion scientists who describe and detail their approaches, methodologies and findings. It is the first to synthesize complementary advances in Biomechanical modelling of living organs using reduced order techniques in the design of medical devices and clinical interventions, including surgical procedures. This book provides an opportunity for students, researchers, clinicians and engineers to study the main topics related to biomechanics and reduced models in a single reference, with this volume summarizing all biomechanical aspects of each living organ in one comprehensive reference. Introduces the fundamental aspects of reduced order models Presents the main computational studies in the field of solid and fluid biomechanical modeling of living organs Explores the use of reduced order models in the fields of biomechanical electrophysiology, tissue growth and prosthetic designs
| Author | : Giovanni P. Galdi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 512 |
| Release | : 2008-03-18 |
| Genre | : Medical |
| ISBN | : 3764378050 |
This book surveys research results on the physical and mathematical modeling, as well as the numerical simulation of complex fluid and structural mechanical processes occurring in the human blood circulation system. Topics treated include continuum mechanical description; choice of suitable liquid and wall models; mathematical analysis of coupled models; numerical methods for flow simulation; parameter identification and model calibration; fluid-solid interaction; mathematical analysis of piping systems; particle transport in channels and pipes; artificial boundary conditions, and many more. The book was developed from lectures presented by the authors at the Oberwolfach Research Institute (MFO), in Oberwolfach-Walke, Germany, November, 2005.
