Benzodiazepine Receptor Inverse Agonists

Benzodiazepine Receptor Inverse Agonists
Author: Martin Sarter
Publisher: Wiley-Liss
Total Pages: 328
Release: 1995-01-23
Genre: Medical
ISBN:

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Provides a comprehensive overview of the biochemical, pharmacological and behavioral research on benzodiazepine receptor (BZR) inverse agonists. Emphasis is given to psychopharmacological potential (including cognitive and motivational enhancement) andtreatment applications (ethanol-antagonism, movement disorders, head injury). The book contains black-and-white illustrations.

The Benzodiazepine Receptor

The Benzodiazepine Receptor
Author: Walter Erhard Müller
Publisher: Cambridge University Press
Total Pages: 208
Release: 1987-12-10
Genre: Medical
ISBN: 9780521304184

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Benzodiazepines are the most commonly used psychotropic drugs, prescribed for their action as tranquillizers, hypnotics and anti-epileptics. They act in the brain by binding to specific, highly selective recognition sites, the benzodiazepine receptors. This book, first published in 1987, summarises our knowledge of these receptors for a student and professional audience and is divided into two sections. In the first part, the general properties of the receptors and their involvement in the mechanisms of action of benzodiazepines are described. The second part discusses the function of the receptors and concludes that the system represents a novel neuronal system for the fine adjustment of brain function or for auxiliary function if the other neuronal systems fail owing to pathological defects.

Benzodiazepine Receptor Ligands, Memory and Information Processing

Benzodiazepine Receptor Ligands, Memory and Information Processing
Author: Ian Hindmarch
Publisher: Springer Science & Business Media
Total Pages: 322
Release: 2013-03-12
Genre: Medical
ISBN: 3642732887

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The following papers were presented at an international workshop on benzo diazepine receptor ligands, memory and information processing, held during the 15th CINP meeting in Puerto Rico in December 1986 and organised by the editors and T. Roth. This workshop was aimed at reviewing and reflecting on past experience with benzodiazepines, evaluating the current state of knowledge of the actions of psychotropic orugs (particularly benzodiazepines, fJ-carbolines and benzodiazepine antagonists), and laying a basis of interest and speculation for future research into the potential use of these drugs in disorders of memory and information processing. There is much published material regarding the theoretical underpinnings of what psychologists call "memory", and doubtless there will be several more libraries filled with theses on the topic before a consensus is reached as regards basic definitions or even meaningful distinctions between for example, "short" and "long"-term memory - everyone has his own particular theory. The qualitative and quantitative diversity of the different approaches might seem to present an insurmountable problem for the psychologist seeking a unified conceptual framework. In practice the various theories produce a plethora of pragmatic and experimental techniques for psychopharmacologists and clinicians to use when investigating drugs with putative amnestic or promnestic properties.

The GABAA/Benzodiazepine Receptor as a Target for Psychoactive Drugs

The GABAA/Benzodiazepine Receptor as a Target for Psychoactive Drugs
Author: Adam Doble
Publisher: Springer
Total Pages: 300
Release: 1996-08
Genre: Medical
ISBN:

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This book traces the development of our understanding of molecular mechanisms of action of benzodiazepines and demonstrates the potential of basic research in the development of improved therapies in psychiatry. The aim is to provide an explanation of the mechanism of action of a commonly used group of psychoactive drugs, to explore future opportunities for the development of new psychotropic drugs and to provide an overview of the pharmacology of an important group of drugs to non-specialist audiences.

Benzodiazepine/GABA Receptors and Chloride Channels

Benzodiazepine/GABA Receptors and Chloride Channels
Author: Richard W. Olsen
Publisher:
Total Pages: 376
Release: 1986
Genre: Medical
ISBN:

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The fifth volume in the series is the first to deal exclusively with a single type of receptor. Contributions represent the most up-to-date research in the benzodiazepine/GABA receptor-chloride channel complex, an extremely interesting protein of great neurobiological significance. Major workers in the field describe the history of GABA receptors and the benzodiazepine connection''. Lays out background material in a particularly clear fashion to allow readers from outside the field to quickly grasp the main points. Presents in detail the allosteric interactions between the various components of the benzodiazepine/GABA receptor complex from the points of view of several authors, so that readers can choose their level of involvement with these details. Includes the most recent advances on the biochemical purification, characterization, and development of monoclonal antibodies for the benzodiazepine/GABA receptor protein.

5-HT1A Agonists, 5-HT3 Antagonists and Benzodiazepines

5-HT1A Agonists, 5-HT3 Antagonists and Benzodiazepines
Author: R. J. Rodgers
Publisher: John Wiley & Sons
Total Pages: 414
Release: 1991
Genre: Medical
ISBN:

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Topics covered in this volume include benzodiazepine receptors and their ligands, effects of benzodiazepines and 5-HT(1A) agonists on learning and memory and physiological and pharmacological implications of specific effects of 5-HT(1A) agonists on rat sexual behaviour.