Bacterial Vaccines In Clinical And Preclinical Development 2021
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Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 92 |
Release | : 2022-07-12 |
Genre | : Medical |
ISBN | : 9240052453 |
Download Bacterial vaccines in clinical and preclinical development 2021 Book in PDF, Epub and Kindle
Author | : World Health Organization |
Publisher | : |
Total Pages | : 0 |
Release | : 2022 |
Genre | : |
ISBN | : |
Download Bacterial Vaccines in Clinical and Preclinical Development 2021: An Overview and Analysis Book in PDF, Epub and Kindle
Author | : Ronald W. Ellis |
Publisher | : Springer Science & Business Media |
Total Pages | : 379 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1461500532 |
Download New Bacterial Vaccines Book in PDF, Epub and Kindle
New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The increase in drug resistance among many bacterial species has increased the need for new bacterial vaccines. This book serves as a comprehensive reference on the major aspects of developing new bacterial vaccines. The distinctive feature of this book is that it focuses upon new vaccines now under development by reviewing key issues for each vaccine target and new technologies being applied to developing new vaccines. This book should prove useful for students in the life sciences, scientists, developers of vaccines and biotechnology products, clinicians, regulators, and health-care practitioners.
Author | : Dlawer A. A. Ala'Aldeen |
Publisher | : |
Total Pages | : 382 |
Release | : 1995-08-08 |
Genre | : Medical |
ISBN | : |
Download Molecular and Clinical Aspects of Bacterial Vaccine Development Book in PDF, Epub and Kindle
Preventable bacterial infections continue to be a major hazard to human health in an age which has experienced a proliferation in readily available vaccines for such diseases. Molecular and Clinical Aspects of Bacterial Vaccine Development examines the latest developments in bacterial vaccinology and the impact they have had on the control of bacterial infections by comprehensively reviewing old, current and future vaccines. Ten of the most globally prevalent bacterial pathogens are covered, providing an indepth analysis of novel strategies for vaccine design and of the state-of-the-art technology available in this field. This timely and authoritative review of vaccine development will be an essential source of information for scientists, clinicians and public health specialists, as well as postgraduate students in relevant fields.
Author | : P.J. Sansonetti |
Publisher | : Springer Science & Business Media |
Total Pages | : 151 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 3642772382 |
Download Pathogenesis of Shigellosis Book in PDF, Epub and Kindle
Shigellosis is present all over the world. Anyone traveling in developing countries knows that the control of this invasive disease of the intestine is a priority task for physicians and public health authorities. Victims are essentially young children, and complications such as the hemolytic uremic syndrome make shigellosis a systemic disease rather than simply an infection of the colonic mucosa. However, "Westerners" should not consider shigeJlosis as an unlikely threat of the tropics. The disease arises in industrialized countries as soon as breaches in sanitation appear. A few months ago, at least 500 people developed shigellosis in northern France in an outbreak of Shigella sonnei infection due to accidental contamination of an urban water delivery system. The pathogenesis of shigellosis is an extraordinary topic of research because study of the invasion of the colonic mucosa addresses fundamental questions on. the molecular and cellular mechanisms by which a bacterial pathogen can pene trate non phagocytic cells, survive, multiply, spread in the intra cellular compartment, and eventually kill host cells. Further development of the infection within subepithelial tissues as well as the mechanisms that contribute to the eradication of this process have barely been studied.
Author | : Hiroshi Kiyono |
Publisher | : Elsevier |
Total Pages | : 501 |
Release | : 1996-10-23 |
Genre | : Medical |
ISBN | : 0080537057 |
Download Mucosal Vaccines Book in PDF, Epub and Kindle
This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization
Author | : René Roy |
Publisher | : ACS Symposium |
Total Pages | : 0 |
Release | : 2008 |
Genre | : Science |
ISBN | : 9780841239838 |
Download Carbohydrate-based Vaccines Book in PDF, Epub and Kindle
This book is the first of its kind entirely dedicated to carbohydrate vaccines written by renowned scientists with expertise in carbohydrate chemistry and immunochemistry. It covers the synthesis of carbohydrate antigens related to bacteria and parasites such as: Heamophilus influenza, Streptococcus pnemoniae, Shigella flexneri, Candida albicans, Mycobacterium tuberculosis, and Chlamydia. The first three chapters are of wide interest as they cover fundamental concerns in new vaccine developments. The first one presents the immune system and how carbohydrate antigens are processed before protective antibodies are produced. It also illustrates antigen presentation in the context of major histocompatibility complexes (MHCs). The second chapter describes regulatory issues when carbohydrate vaccines are involved while the third one discuss several techniques used in conjugation chemistry and the implication of certain chemical linkages that may induce unexpected anti-linker antibodies. This section will be particularly appealing for those involved in drug-conjugate design, pro-drug developments, and drug vectorization. The book concludes with one chapter that illustrates the principle through which peptide antigens can functionally mimic carbohydrate epitopes, thus, unraveling the potential for peptide surrogates as replacement for complex carbohydrate structures. This book is unique in that it covers all aspects related to carbohydrate vaccines including the success story with the first semi-synthetic bacterial polysaccharide vaccine against Heamophilus influenza type b responsible for pneumonia and meningitis, liable for more than 600,000 infant deaths worldwide in developing countries. The book also presents regulatory issues and will thus be vital for government agencies approving candidate vaccines. It widely covers synthetic methodologies for the attachment of carbohydrate antigens to peptides and immunogenic protein carriers. Vaccines against bacterial antigens, cancer, and parasites are also discussed by worldwide experts in this field in details. No other book contains such a wide panel of different expertise. It will also be useful to students and researchers involved with the immunology of forreings antigens and how the under appreciated carbohydrate antigens are processed by the immune system.
Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 42 |
Release | : 2024-05-28 |
Genre | : Medical |
ISBN | : 9240093982 |
Download WHO Evidence Considerations for Vaccine Policy Development for Tuberculosis Vaccines Intended for Adults and Adolescents Book in PDF, Epub and Kindle
This ECVP is a new technical product that aims to anticipate and collectively delineate the clinical trial, observational and other data likely to be required by global and national policy-makers, and to do so when most valuable – during development of the late-stage clinical plan, including the design of the pivotal licensure trial. Proactively generating this evidence as part of or in parallel to clinical development – where feasible – rather than reactively post-licensure, creates an opportunity to accelerate vaccine policy formulation, adoption and impact, particularly in LMICs.
Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 72 |
Release | : 2024-05-17 |
Genre | : Medical |
ISBN | : 924009346X |
Download WHO bacterial priority pathogens list, 2024 Book in PDF, Epub and Kindle
Author | : World Health Organization |
Publisher | : World Health Organization |
Total Pages | : 197 |
Release | : 2023-12-12 |
Genre | : Medical |
ISBN | : 924007466X |
Download Implementing the global action plan on antimicrobial resistance Book in PDF, Epub and Kindle