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| Author | : Denis Thieffry |
| Publisher | : Humana Press |
| Total Pages | : 560 |
| Release | : 2016-05-01 |
| Genre | : Science |
| ISBN | : 9781493961566 |
Bacterial Molecular Networks provides authoritative descriptions of various experimental and computational methods that enable the characterization and analysis of molecular interaction networks.
| Author | : |
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| Total Pages | : |
| Release | : 2009 |
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The project examined a number of aspects of complex bacterial networks, their architecture, topology, dynamics and design principles.
| Author | : Bruce Alberts |
| Publisher | : |
| Total Pages | : 0 |
| Release | : 2002 |
| Genre | : Cytology |
| ISBN | : 9780815332183 |
| Author | : Ryutaro Utsumi |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 257 |
| Release | : 2008-12-05 |
| Genre | : Medical |
| ISBN | : 0387788859 |
This fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been unearthed.
| Author | : Stephen J. Hagen |
| Publisher | : Springer |
| Total Pages | : 257 |
| Release | : 2014-09-29 |
| Genre | : Science |
| ISBN | : 1493914022 |
Quorum sensing (QS) describes a chemical communication behavior that is nearly universal among bacteria. Individual cells release a diffusible small molecule (an autoinducer) into their environment. A high concentration of this autoinducer serves as a signal of high population density, triggering new patterns of gene expression throughout the population. However QS is often much more complex than this simple census-taking behavior. Many QS bacteria produce and detect multiple autoinducers, which generate quorum signal cross talk with each other and with other bacterial species. QS gene regulatory networks respond to a range of physiological and environmental inputs in addition to autoinducer signals. While a host of individual QS systems have been characterized in great molecular and chemical detail, quorum communication raises many fundamental quantitative problems which are increasingly attracting the attention of physical scientists and mathematicians. Key questions include: What kinds of information can a bacterium gather about its environment through QS? What physical principles ultimately constrain the efficacy of diffusion-based communication? How do QS regulatory networks maximize information throughput while minimizing undesirable noise and cross talk? How does QS function in complex, spatially structured environments such as biofilms? Previous books and reviews have focused on the microbiology and biochemistry of QS. With contributions by leading scientists and mathematicians working in the field of physical biology, this volume examines the interplay of diffusion and signaling, collective and coupled dynamics of gene regulation, and spatiotemporal QS phenomena. Chapters will describe experimental studies of QS in natural and engineered or microfabricated bacterial environments, as well as modeling of QS on length scales spanning from the molecular to macroscopic. The book aims to educate physical scientists and quantitative-oriented biologists on the application of physics-based experiment and analysis, together with appropriate modeling, in the understanding and interpretation of the pervasive phenomenon of microbial quorum communication.
| Author | : Spiros Paramithiotis |
| Publisher | : CRC Press |
| Total Pages | : 252 |
| Release | : 2019-02-14 |
| Genre | : Science |
| ISBN | : 1351615106 |
With the advances in the field of molecular biology, new tools make it possible to conduct in-depth studies in food microbial communities from a molecular perspective. Information from genomic, transcriptomic, proteomic and metabolomic studies can be integrated through bioinformatic applications, thereby improving our understanding of the interactions between biotic and abiotic factors and concomitantly the physiology of starter cultures, spoilage and pathogenic microbiota. Improvements in the speed, accuracy and reliability of food quality and safety assessment have made the foundation stronger for future developments including the exploitation of gene networks and applications of nanotechnology and systems biology. This book reviews all these developments, provides an integrated view of the subject and helps in identifying areas of future development.
| Author | : Carlos E. Hormaeche |
| Publisher | : Cambridge University Press |
| Total Pages | : 343 |
| Release | : 1992-10-22 |
| Genre | : Science |
| ISBN | : 9780521432986 |
Understanding virulence determinants of bacterial pathogens and their regulation, and the pathogenesis of bacterial infections, is essential to the development of safe and effective vaccines and therapeutic strategies. This book presents an authoritative account of the contributions being made by molecular genetics and improved analytical technology in uncovering the molecular basis of bacteria-host interactions in infections. The broad scope of the volume encompasses normal flora and colonization resistance, evolution of pathogenic mechanisms, genetic approaches to understanding bacterial pathogenesis and in vivo studies of mutants, antigenic variation, bacterial invasion, toxins, environmental control of gene expression, regulatory networks in gene control, and attenuation of virulence through auxotrophy. The book will provide a state of the art reference for researchers in all areas concerned with bacterial infection and will also be useful as an advanced text.
| Author | : Alain Filloux |
| Publisher | : Caister Academic Press Limited |
| Total Pages | : 0 |
| Release | : 2012 |
| Genre | : Science |
| ISBN | : 9781908230034 |
Regulatory networks enable bacteria to adapt to almost every environmental niche on earth. Regulation is achieved by a network of interactions among diverse types of molecules including DNA, RNA, proteins and metabolites. The primary role of regulatory networks in bacteria is to control the response to environmental changes, such as nutritional status and environmental stress. A complex organization of networks allows the organism to coordinate and integrate multiple environmental signals. Renowned authors under the expert guidance of the editor Alain A.M. Filloux, have contributed authoritative, up-to-date reviews of the current research and theories on regulatory networks in bacteria. The volume contains critical reviews written by the leading research scientists in this topical field. The authors fully explore various regulatory networks, discuss variations of common themes and provide fresh insights into bacterial regulatory mechanisms. Topics include: the sigma network in Escherichia coli, control of bacterial virulence, ECF sigma factors, quorum sensing, cyclic di-GMP, RNA-mediated regulation, the H-NS regulator, two-component regulatory systems, bacterial chemotaxis, regulation of iron homeostasis, anaerobic regulatory networks, bacterial bistable regulatory networks, and evolution of transcription factors and regulatory networks. This book is essential reading for everyone interested in gene expression and regulation in bacteria and is a recommended text for all microbiology libraries.
| Author | : Uldis N. Streips |
| Publisher | : John Wiley & Sons |
| Total Pages | : 673 |
| Release | : 2004-03-24 |
| Genre | : Science |
| ISBN | : 0471461083 |
In accordance with its predecessor, the completely revised and expanded Second Edition of Modern Microbial Genetics focuses on how bacteria and bacteriophage arrange and rearrange their genetic material through mutation, evolution, and genetic exchange to take optimal advantage of their environment. The text is divided into three sections: DNA Metabolism, Genetic Response, and Genetic Exchange. The first addresses how DNA replicates, repairs itself, and recombines, as well as how it may be manipulated. The second section is devoted to how microorganisms interact with their environment, including chapters on sporulation and stress shock, and the final section contains the latest information on classic exchange mechanisms such as transformation and conjugation. Chapters include: * Gene Expression and Its Regulation * Single-Stranded DNA Phages * Genetic Tools for Dissecting Motility and Development of Myxococcus xanthus * Molecular Mechanism of Quorum Sensing * Transduction in Gram-Negative Bacteria * Genetic Approaches in Bacteria with No Natural Genetic Systems The editors also cultivate an attention to global regulatory systems throughout the book, elucidating how certain genes and operons in bacteria, defined as regulons, network and cooperate to suit the needs of the bacterial cell. With clear appreciation for the impact of molecular genomics, this completely revised and updated edition proves that Modern Microbial Genetics remains the benchmark text in its field.
| Author | : Axel Mogk |
| Publisher | : Frontiers Media SA |
| Total Pages | : 334 |
| Release | : 2022-02-01 |
| Genre | : Science |
| ISBN | : 2889741931 |
The Cover Image for This Research Topic is Used With Permission of the Authors and Publishers of the Following Article: Winkler J, Seybert A, König L, Pruggnaller S, Haselmann U, Sourjik V, Weiss M, Frangakis AS, Mogk A, Bukau B.EMBO J. 2010 Mar 3;29(5):910-23. doi: 10.1038/emboj.2009.412. Epub 2010 Jan 21
