In the spirit of medieval writer Chaucer, all human activity lies within the artist’s scope, the History of Man Series uses medicine as a jumping off point to explore precisely that, all history, all science, all human activity since the beginning of time. The jumping off style of writing takes the reader, the listener into worlds unknown, always returning to base, only to jump off again. History of Man are stories and tales of nearly everything. The Sixth History of Man is the last narrative in the History of Man Series that uses infection as the underlying foundation. The series will continue but use other disease platforms for jumping off. From a human infection perspective, this sixth book will visit with the King of Pop Michael Jackson, vitiligo and propofol, the famous and infamous sexually transmitted diseases—herpes, gonorrhea, chlamydia, trichomonas, HIV and the granddaddy of colorful stories, syphilis—with their very entertaining tales, a world of romance, suspense, and thrillers. We’ll hop from science to art to music, going back in time to the astronomy of the Persians, Syrians, the Greek Aristotle and on to Ptolemy, Copernicus and Kepler. Our travels will take us to the Renaissance of art and music, stopping along a few stations, such as da Vinci, Michelangelo, Rembrandt, and Monet. A discussion of why and how humans went from spoken language to written language is on our menu. We will pay homage with another visit with the First Viennese School, parse senility, delirium, and dementia and most assuredly discuss the women who helped build Johns Hopkins Hospital. OK Boomers! and the sociology of cohort generations will help complete this narrative.