Applications of Infrared Spectroscopy in Biochemistry, Biology, and Medicine

Applications of Infrared Spectroscopy in Biochemistry, Biology, and Medicine
Author: Frank Parker
Publisher: Springer Science & Business Media
Total Pages: 612
Release: 2012-12-06
Genre: Science
ISBN: 1468418726

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This book is not intended to be a basic text in infrared spectroscopy. Many such books exist and I have referred to them in the text. Rather, I have tried to find applications that would be interesting to a variety of people: advanced undergraduate chemistry students, graduate students and research workers in several disciplines, spectros copists, and physicians active in research or in the practice of medicine. With this aim in mind there was no intent to have exhaustive coverage of the literature. I should like to acknowledge my use of several books and reviews, which were invaluable in my search for material: G. H. Beaven, E. A. Johnson, H. A. Willis and R. G. 1. Miller, Molecular Spec troscopy, Heywood and Company, Ltd., London, 1961. J. A. Schell man and Charlotte Schellman, 'The Conformation of Polypeptide Chains in Proteins," in The Proteins, Vol. II, 2nd Ed. (H. Neurath, ed.), Academic Press, New York, 1964. R. T. O'Connor, "Application of Infrared Spectrophotometry to Fatty Acid Derivatives," J. Am. Oil Chemists' Soc. 33, 1 (1956). F. L. Kauffman, "Infrared Spectroscopy of Fats and Oils," J. Am. Oil Chemists' Soc. 41,4 (1964). W. J. Potts, Jr., Chemical Infrared Spectroscopy, Vol. I, Techniques, Wiley, New York, 1963. R. S. Tipson, Infrared Spectroscopy of Carbohydrates, National Bureau of Standards Monograph llO, Washington, D.C., 1968. C. N. R. Rao, Chemical Applications of Infrared Spectroscopy, Academic Press, New York, 1963.

Biological and Biomedical Infrared Spectroscopy

Biological and Biomedical Infrared Spectroscopy
Author: A. Barth
Publisher: IOS Press
Total Pages: 448
Release: 2009-09-02
Genre: Medical
ISBN: 160750457X

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Although infrared spectroscopy has been applied with success to the study of important biological and biomedical processes for many years, key advances in this vibrant technique have led to its increasing use, ranging from characterisation of individual macromolecules (DNA, RNA, lipids, proteins) to human tissues, cells and their components. Infrared spectroscopy thus has a significant role to play in the analysis of the vast number of genes and proteins being identified by the various genomic sequencing projects. Whilst this book gives an overview of the field it highlights more recent developments, such as the use of bright synchrotron radiation for recording infrared spectra, the development of two-dimensional infrared spectroscopy and the ability to record infrared spectra at ultrafast speeds. The main focus is on the mid-infrared region, since the great majority of studies are carried out in this region but there is increasing use of the near infrared for biomedical applications and a chapter is devoted to this part of the spectrum. Major advances in theoretical analysis have also enabled better interpretation of the infrared spectra of biological molecules and these are covered. The editors, Professor Andreas Barth of Stockholm University, Stockholm, Sweden and Dr Parvez I. Haris of De Montfort University, Leicester, U.K., who both have extensive research experience in biological infrared spectroscopy per se and in its use in the solution of biophysical problems, have felt it timely therefore to bring together this book. The book is intended for use both by research scientists already active in the use of biological infrared spectroscopy and for those coming new to the technique. Graduate students will also find it useful as an introduction to the technique.

Biological Applications of Infrared Spectroscopy

Biological Applications of Infrared Spectroscopy
Author: Barbara H. Stuart
Publisher: John Wiley & Sons
Total Pages: 220
Release: 1997-08-04
Genre: Science
ISBN: 9780471974147

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Diese Einführung in die Grundlagen der Infrarot-Spektroskopie ist besonders für Biologen und Biochemiker gedacht. Von den theoretischen Grundlagen über experimentelle Methoden und instrumentelle Ausrüstung bis hin zur Interpretation von Spektren biologisch relevanter Spezies (Proteine, Peptide, Lipide, Nucleinsäuren, Membranen) wird das Gebiet umfassend und auch für Nichtspezialisten verständlich behandelt.

Optical Spectroscopy and Computational Methods in Biology and Medicine

Optical Spectroscopy and Computational Methods in Biology and Medicine
Author: Malgorzata Baranska
Publisher: Springer Science & Business Media
Total Pages: 540
Release: 2013-12-05
Genre: Science
ISBN: 9400778325

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This multi-author contributed volume gives a comprehensive overview of recent progress in various vibrational spectroscopic techniques and chemometric methods and their applications in chemistry, biology and medicine. In order to meet the needs of readers, the book focuses on recent advances in technical development and potential exploitations of the theory, as well as the new applications of vibrational methods to problems of recent general interest that were difficult or even impossible to achieve in the not so distant past. Integrating vibrational spectroscopy and computational approaches serves as a handbook for people performing vibrational spectroscopy followed by chemometric analysis hence both experimental methods as well as procedures of recommended analysis are described. This volume is written for individuals who develop new methodologies and extend these applications to new realms of chemical and medicinal interest.

Application of Near Infrared Spectroscopy in Biomedicine

Application of Near Infrared Spectroscopy in Biomedicine
Author: Thomas Jue
Publisher: Springer Science & Business Media
Total Pages: 156
Release: 2013-03-20
Genre: Medical
ISBN: 1461462525

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In keeping with the style of the Handbook of Modern Biophysics, this fourth volume, Application of Near-Infrared Spectroscopy in Biomedicine, balances the need for physical science/mathematics formalism with a demand for biomedical perspectives. Each chapter divides the presentation into two major parts: the first establishes the conceptual framework and describes the instrumentation or technique, while the second illustrates current applications in addressing complex biology questions. With the additional sections on further reading, problems, and references, the interested reader can explore some chapter ideas more widely.

Infrared Spectroscopy

Infrared Spectroscopy
Author: Daniel Cozzolino
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2014
Genre: Infrared spectroscopy
ISBN: 9781629485218

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Since Herschel discovered light in the near-infrared region as early as 1800, the NIR region of the electromagnetic spectrum, once regarded as having little potential for analytical work, has now become one of the most promising techniques for molecular spectroscopy in several analytical fields. Over the last three decades, the development of new applications of infrared spectroscopy has been associated with increased power of computers and progress in chemometrics. This book introduces and presents several novel applications of NIR spectroscopy in biology, medicine, food science, the pharmaceutical sciences, polymers and minerals, for the first time in a single book. It is written by an international panel of scientists with a vast expertise in the field of infrared spectroscopy, providing unique views and perspectives on both practical and theoretical applications. This book should serve as a reference source for undergraduate and postgraduate students, scientists and researchers in the field of infrared spectroscopy.

Spectroscopy of Biological Molecules

Spectroscopy of Biological Molecules
Author: Camille Sandorfy
Publisher: Springer Science & Business Media
Total Pages: 639
Release: 2012-12-06
Genre: Science
ISBN: 9400964900

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This volume contains the proceedings of the NATO-Advanced Study Institute on the "Spectroscopy of Biological Molecules", which took place on July 4-15, 1983 in Acquafredda di Maratea, Italy. The institute concentrated on three main subiects: the structure and dymanics of DNA, proteins, and visual and plant pigments. Its timeliness has been linked to rapid advances in certain spectroscopic techniques which yielded a consider able amount of new information on the structure and inter actions of biologically important molecules. Among these techniques Fourier transform infrared, resonance and surface enhanced 'Raman spectroscopies, Raman microscopy and micro probing, time resolved techniques, two photon and ultrafast electronic, and C-13, N-15 and P-31 NMR spectroscopies and kinetic and static IR difference spectroscopy receiced a great deal of attention at the Institute. In addition, an entirely new technique, near-millimeter-wave spectroscopy has been presented and discussed. Two introductory quantum chemical lectures, one on the structure of water in DNA, and another pn the energy bands in DNA and proteins set the stage for the experimentally oriented lectures that followed. Fundamental knowledge on hydrogen bonding was the topic of two other lectures. Panel discussions were held on the structure and confor mations of DNA, metal-DNA adducts and proteins and on visual pigments. Many scientists who normally attend different conferences and never meet, met at Aquafredda di Maratea. We feel, that at the end of our Institute a synthetic vi~w emerged on the powerful spectroscopic and theoretical methods which are now available for the study of biological molecules.