"Aboriginal [First Nations, Native peoples] communities in the northern Ontario region utilize an abundance of locally grown medicinal plants. However, no prior documentation or phytochemical studies on the northern Ontario medicinal plants existed in literature. This prompted me to exploit the ethnobotanical resources in this region towards the study of antibacterial bioactivity and alleviation of oxidative stress. Oxidative stress plays a fundamental role in the pathogenesis of many major human illnesses, such as cancer, cardiovascular diseases, diabetes and Alzheimer's syndrome. Also, infectious diseases are a major concern in our society due to the advent of multiple drug resistant strains of bacteria that cause millions of mortalities worldwide. From the accumulated list of 48 northern Ontario medicinal plants, I selected 21 plants based on their documented anticancer, antibacterial, antioxidant, antidiarrheal and anti-inflammatory properties. These plants were separated into leaf, flower, stem and root tissues and extracted with ethanol. In total, 43 extracts were assayed for antioxidant and antibacterial activity in this study. The antioxidant activity was evaluated through the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt), ORAC (Oxygen radical absorption capacity), and EC 50 (half maximal effective concentration) assays. The total phenolic content of medicinal plants was also determined.