Scanning Electron Microscopy of Cerebellar Cortex

Scanning Electron Microscopy of Cerebellar Cortex
Author: Orlando Castejón
Publisher: Springer Science & Business Media
Total Pages: 140
Release: 2012-12-06
Genre: Medical
ISBN: 1461501598

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In a clear exposition this inspirational book shows the in situ three-dimensional morphology of cerebellar neurons, intracortical circuits and synaptic connections that underpin the functioning of cerebellar neurons in networks. It brings together in one volume a new view of the three-dimensional cytoarchitectonic arrangement of the cerebellar cortex. The book shows the cerebellar extrinsic and intrinsic intracortical circuits formed by mossy and climbing fibers as exposed by the cryofracture methods. The high degree of lateral collateralization of these fibers is also displayed providing new insights on the information processing in the cerebellar cortex. Besides, field emission high resolution electron microscopy shows its potential contribution to the study of synaptic morphology. The concluding chapter deals with the contribution of scanning electron microscopy to cerebellar neurobiology. This monograph is an authoritative survey and a must for anyone who is interested in the structure of the central nervous system. It will also appeal to an interdisciplinary audience who wants to learn more about electron microscopy and neurocytology.

Cerebellar Cortex

Cerebellar Cortex
Author: S.L. Palay
Publisher: Springer Science & Business Media
Total Pages: 361
Release: 2012-12-06
Genre: Medical
ISBN: 3642655815

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The origins of this book go back to the first electron microscopic studies of the central nervous system. The cerebellar cortex was from the first an object of close study in the electron microscope, repeating in modern cytology and neuroanatomy the role it had in the hands of RAMON y CAJAL at the end of the nineteenth century. The senior author vividly remembers a day early in 1953 when GEORGE PALADE, with whom he was then working, showed him an electron micrograph of a cerebellar glomerulus, saying "That is what the synapse should look like. " It is true that the tissue was swollen and the mitochondria were exploded, but all of the essentials of synaptic structure were visible. At that time small fragments of tissue, fixed by immersion in osmium tetroxide and embedded in methacrylate, were laboriously sectioned with glass knives without any predetermined orientation and then examined in the electron microscope. After much searching, favorably preserved areas' were studied at the cytological level in order to recognize the parts of neurons and characterize them. Such procedures, dependent upon random sections and uncontrollable selection by a highly erratic technique of preservation, precluded any systematic investigation of the organization of a particular nucleus or region of the central nervous system. It was difficult enough to distinguish neurons from the neuroglia.

The Cerebellum Revisited

The Cerebellum Revisited
Author: Rodolfo Llinas
Publisher: Springer Science & Business Media
Total Pages: 354
Release: 2012-12-06
Genre: Medical
ISBN: 1461228409

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This book is organized into three parts that correspond with the main groups of chapters delivered during the Cajal Centenary Meeting on The Neutron Doctrine. These chapters represent important aspects of the morphology, development, and function of the cerebellum and related structures. Clearly an exhaustive analysis of all aspects of the cerebellar system, as they relate to the legacy of Ramon y Cajal, would be impossible to contain in just one volume, given its far-reaching impact. Instead, we deliberately steered away from the traditional handbook approach that some of us have taken in the past and selected those aspects of cerebellar research currently under vigorous study that would also represent the widest scope of interest for neuroscientists in general and for cerebellar specialists in particular. In particular, we felt that as the discrete anatomy of the cerebellum is quite well known, only certain aspects of the structure should be discussed here. For example, the organization of the pontocerebellar pathways, we felt, would be particularly interesting given the enormity of the system in higher vertebrates. Also of interest is the distribution and development of the synaptology and neurotransmitter properties in this cortex. Indeed, from the point of view of cerebellar development, this may represent one of the clearest paradigms in the understanding of rules for neurogenesis for the central nervous system.

Filling in the Gaps

Filling in the Gaps
Author: Jennifer Robinson
Publisher:
Total Pages:
Release: 2010
Genre:
ISBN:

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Principles of Neural Science

Principles of Neural Science
Author: Eric R. Kandel
Publisher:
Total Pages: 1135
Release: 1991
Genre: Anatomy
ISBN: 9780838580684

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Astrocytes Pt 1: Development, Morphology, and Regional Specialization of Astrocytes

Astrocytes Pt 1: Development, Morphology, and Regional Specialization of Astrocytes
Author: Sergey Fedorff
Publisher: Elsevier
Total Pages: 395
Release: 2012-12-02
Genre: Medical
ISBN: 0323152473

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Astrocytes: Development, Morphology, and Regional Specialization of Astrocytes, Volume 1 provides an overview of the development and diversity of astrocytes in the whole central nervous system and serves as a guide to the members of the astrocyte family. This volume discusses the phylogenetic and ontogenetic development, the origin, differentiation, and topographical distribution of astrocytes. The text deals mainly with astrocytes in the brains of birds and mammals because of the maximum diversity and specialization of glial cells found in these vertebrates. The book will be of great use to cellular biologists, developmental neurobiologists, pediatric neurologists, neurochemists, neurologists, and neuropathologists.

Quantitative Light and Electron Microscopic Study of Cerebellar Granule Cells and Parallel Fiber Varicosities in Adult Tottering (tg/tg), Leaner (tgla/tgla) and Compound Heterozygous (tg/tgla) Mice

Quantitative Light and Electron Microscopic Study of Cerebellar Granule Cells and Parallel Fiber Varicosities in Adult Tottering (tg/tg), Leaner (tgla/tgla) and Compound Heterozygous (tg/tgla) Mice
Author: Dana B. Walker
Publisher:
Total Pages: 236
Release: 1998
Genre:
ISBN:

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