Alzheimer's Disease and Air Pollution

Alzheimer's Disease and Air Pollution
Author: L. Calderón-Garcidueñas
Publisher: IOS Press
Total Pages: 616
Release: 2021-05-03
Genre: Medical
ISBN: 1643681591

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Most people think of Alzheimer’s disease as a condition which predominately affects elderly people, but an increasing amount of evidence indicates that in populations exposed to high concentration of air pollutants, Alzheimer’s disease development and progression can be identified in pediatric and young adulthood ages. Cognitive, olfactory, gait, equilibrium and auditory alterations are seen early, thus the concept of decades-long asymptomatic period prior to clinical cognitive impairment does not apply to the millions of people exposed day in and day out to polluted environments. This book Alzheimer's Disease and Air Pollution – The Development and Progression of a Fatal Disease from Childhood and the Opportunities for Early Prevention is a compilation of work by researchers intent on revealing the links between air pollution and neurodegeneration. The book is divided into 6 sections. It includes a section describing the ways in which air pollution from traffic and tobacco smoke can damage the brain; epidemiological studies establishing a strong link between dementia and particulate matter and ozone; papers explaining the properties of pollution; and works describing the intricate pathways which transform normal neurons into ghost tangles surrounded by a devastated brain. Air pollution is complex; different pollutants, different sizes and shapes and different portals of entry, play different roles, but their capacity to damage neural tissue is abundantly illustrated in this book, which highlights the need for preventive measures to protect the millions of people currently exposed to air pollutants, and the need to ameliorate their harmful effects.

Early Diagnosis of Alzheimer’s Disease

Early Diagnosis of Alzheimer’s Disease
Author: Leonard F. M. Scinto
Publisher: Springer Science & Business Media
Total Pages: 366
Release: 2000-02-09
Genre: Medical
ISBN: 1592590055

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Drs. Leonard Scinto and Kirk Daffner provide a comprehensive survey of new diagnostic approaches to Alzheimer's disease. The authoritative contributors critically survey the most promising current research on early diagnostic markers for Alzheimer's disease, including the elucidation of changes in the brain revealed by structural and functional neuroimaging, as well as the characteristic patterns of cognitive decline that are documented by sensitive neuropsychological tests, various genetic markers, and biological assays. Early Diagnosis of Alzheimer's Disease illuminates the complex issues surrounding the search for early markers of this increasingly widespread disease. It will establish a new standard reference guide for all those working with Alzheimer's patients.

Neurological Disorders

Neurological Disorders
Author: World Health Organization
Publisher: World Health Organization
Total Pages: 233
Release: 2006
Genre: Medical
ISBN: 9241563362

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Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.

The Role of Global Air Pollution in Aging and Disease

The Role of Global Air Pollution in Aging and Disease
Author: Caleb E. Finch
Publisher: Academic Press
Total Pages: 220
Release: 2018-01-21
Genre: Medical
ISBN: 0128131039

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Global Air Pollution in Aging: Reading Smoke Signals is a complete reference connecting environmental pollution research to the human aging process. Since 1800, lifespans have more than doubled as infections declined and medicine improved. But the 20th century introduced a new global scourge of air pollution from fossil fuels with the potential to damage arteries, hearts and lungs that has been related to chronic exposure of air pollution from fossil fuels. Risk areas of study include childhood obesity, brain damage associated with air pollution, increased risk for autism in children and dementia in older adults. In humans and animals, air pollution stimulates chronic inflammation in different organs, and genetic vulnerability to air pollution is being recognized, particularly for carriers of the Alzheimer risk gene ApoE4. Connects environmental pollution research to the human aging process Raises new issues relevant to the controversies on air pollution and global warming, challenging assumptions that lifespan will continue to increase in the 21st Century Examines the burden of air pollution to disadvantaged populations, with anticipated greater impact in developing countries which rely on fossil fuels for economic development in future decades

Ambient Air Pollution and Health Impact in China

Ambient Air Pollution and Health Impact in China
Author: Guang-Hui Dong
Publisher: Springer
Total Pages: 0
Release: 2018-12-12
Genre: Medical
ISBN: 9789811354557

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This book focuses on the health impacts of air pollution in China, especially the epidemiology-based exposure-response functions for the mortality, morbidity, and hospital admissions for respiratory diseases, cardiovascular diseases, lung cancer, and mental health related to pollution. It also provides the latest estimates of the magnitude of the adverse effects of air pollution on the health of the Chinese population. By providing a better understanding of the impact of air pollution on health, it improves the scientific basis of risk assessment, and also helps governments develop policies and other health protection initiatives to reduce the impacts of air pollution. The book offers environmental scientists, engineers, researchers and students a comprehensive and organized body of information in the area of air pollution.

Dementia and Memory

Dementia and Memory
Author: Lars-Göran Nilsson
Publisher: Psychology Press
Total Pages: 265
Release: 2013-11-20
Genre: Psychology
ISBN: 1317916581

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A negative effect of the ageing population is that more individuals are experiencing cognitive decline and some form of neurodegenerative disease. With the number of people experiencing dementia likely to double in the next 20 years, this change in society presents one of greatest challenges facing public health personnel in the 21st century. The aim of this volume is to describe research that is in progress, and the major findings that have been obtained in the scientific study of dementia. The chapters in the first section of the book focus upon early signs of dementia, and consider several approaches to finding early cognitive signs and biological markers of dementia. The second section considers whether dementia is inevitable for people who become very old, and features chapters on risk factors and proactive influences, cognitive reserve and intervention. Each chapter in the final section describes phenomena which are related to differences in function between memory systems, including anterograde memory in fronto-temporal dementia, and the role semantic memory and semantic cognition may play in developing an understanding of the development of the degenerative processes in dementia. With contributions from world-class researchers in this area, the volume offers a concise overview of key findings in recent research on dementia and memory. It will be of great interest to researchers and advanced students of cognitive psychology, and to those working in related fields, such as gerontology, rehabilitation sciences, and allied health.

Epidemiology of Alzheimer’s Disease: From Gene to Prevention

Epidemiology of Alzheimer’s Disease: From Gene to Prevention
Author: Richard Mayeux
Publisher: Springer Science & Business Media
Total Pages: 140
Release: 2012-12-06
Genre: Medical
ISBN: 364260076X

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This volume contains the proceedings of the 14th Colloque Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique devoted to Alzheimer's Disease and dedicated to the epidemiological study of this dementia, a very important issue because the incidence and prevalence of Alzheimer's Disease rise exponentially with age. Epidemiological findings not only confirm dementia as a major challenge for the coming years but also contribute defining risk factors, predicting and may be preventing this disease.

Genes, Environment and Alzheimer's Disease

Genes, Environment and Alzheimer's Disease
Author: Orly Lazarov
Publisher: Academic Press
Total Pages: 449
Release: 2016-02-25
Genre: Psychology
ISBN: 0128028858

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Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. Provides the first volume to link genetic and environmental risk factors for Alzheimer’s disease and dementia Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer’s disease and cognitive decline Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists

Type 2 Diabetes and Dementia

Type 2 Diabetes and Dementia
Author: Velandai Srikanth
Publisher: Academic Press
Total Pages: 322
Release: 2018-02-09
Genre: Medical
ISBN: 0128096942

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Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications