Accurate Results in the Clinical Laboratory

Accurate Results in the Clinical Laboratory
Author: Amitava Dasgupta
Publisher: Newnes
Total Pages: 383
Release: 2013-01-22
Genre: Science
ISBN: 0124158587
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This practical, easy-to-use guide, named to Doody’s Core Titles 2013, addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management. Named to Doody’s Core Titles 2013, a collection development tool for health sciences libraries of all sizes, by Doody Enterprises Practical information for both clinicians and laboratory scientists, presented in the form of tables and charts for easy reference Focus on range and sources of interferences rather than details of toxicologic mechanisms which are well covered in toxicology textbooks Covers interferences across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing

Medicare Laboratory Payment Policy

Medicare Laboratory Payment Policy
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 261
Release: 2000-12-04
Genre: Medical
ISBN: 0309183618
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Clinical laboratory tests play an integral role in helping physicians diagnose and treat patients. New developments in laboratory technology offer the prospect of improvements in diagnosis and care, but will place an increased burden on the payment system. Medicare, the federal program providing coverage of health-care services for the elderly and disabled, is the largest payer of clinical laboratory services. Originally designed in the early 1980s, Medicare's payment policy methodology for outpatient laboratory services has not evolved to take into account technology, market, and regulatory changes, and is now outdated. This report examines the current Medicare payment methodology for outpatient clinical laboratory services in the context of environmental and technological trends, evaluates payment policy alternatives, and makes recommendations to improve the system.

Endogenous Interferences in Clinical Laboratory Tests

Endogenous Interferences in Clinical Laboratory Tests
Author: Martin H. Kroll
Publisher: Walter de Gruyter
Total Pages: 155
Release: 2012-12-19
Genre: Medical
ISBN: 3110266229
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The goal of clinical laboratories is to produce accurate information for clinical decision making in medicine. More than half of the medical decisions made depend on clinical laboratory tests. Patient safety represents an important and critical problem for laboratories. They need to assure that the information they deliver to physicians is accurate, and therefore safe for clinicians to use. Endogenous compounds can interfere with laboratory tests, decreasing accuracy and threatening patient safety. Elevated bilirubin (bilirubinemia) and elevated lipids (lipemia) are common conditions that cause significant interferences with laboratory results. Clinicians depend on laboratories to detect these endogenous interferences. Laboratories must have a means to detect these endogenous interferences, make decisions about reporting results, and evaluate their impact. Most clinical pathology books provide only an abbreviated introduction to the subject, or provide a long list of references, without the necessary foundation for evaluating their significance. Package inserts typically provide scant information. This book provides the empirical and theoretical foundation for these interferences, describes the clinical settings where they occur, and explains their evaluation and detection, allowing the laboratory to interpret the available data on interferences and make the appropriate decision to effectively report test results while protecting patient safety.

Accurate Results in the Clinical Laboratory

Accurate Results in the Clinical Laboratory
Author: Amitava Dasgupta
Publisher: Elsevier
Total Pages: 510
Release: 2019-07-20
Genre: Medical
ISBN: 0128137770
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Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, Second Edition, provides a comprehensive review of the factors leading to errors in all areas of clinical laboratory testing. This trusted guide addresses interference issues in all laboratory tests, including patient epigenetics, processes of specimen collection, enzymes and biomarkers. Clinicians and laboratory scientists will both benefit from this reference that applies discussions to both accurate specimen analysis and optimal patient care. Hence, this is the perfect reference for clinical laboratorians, from trainees, to experienced pathologists and directors. Provides comprehensive coverage across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing Includes new case studies that highlight clinical relevance and errors to avoid Highlights the best titles published within a variety of medical specialties Reviewed by medical librarians and content specialists, with key selections compiled in their annual list

Mass Spectrometry for the Clinical Laboratory

Mass Spectrometry for the Clinical Laboratory
Author: Hari Nair
Publisher: Academic Press
Total Pages: 306
Release: 2016-11-02
Genre: Science
ISBN: 0128009926
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Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Textbook of Patient Safety and Clinical Risk Management

Textbook of Patient Safety and Clinical Risk Management
Author: Liam Donaldson
Publisher: Springer Nature
Total Pages: 496
Release: 2020-12-14
Genre: Medical
ISBN: 3030594033
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Implementing safety practices in healthcare saves lives and improves the quality of care: it is therefore vital to apply good clinical practices, such as the WHO surgical checklist, to adopt the most appropriate measures for the prevention of assistance-related risks, and to identify the potential ones using tools such as reporting & learning systems. The culture of safety in the care environment and of human factors influencing it should be developed from the beginning of medical studies and in the first years of professional practice, in order to have the maximum impact on clinicians' and nurses' behavior. Medical errors tend to vary with the level of proficiency and experience, and this must be taken into account in adverse events prevention. Human factors assume a decisive importance in resilient organizations, and an understanding of risk control and containment is fundamental for all medical and surgical specialties. This open access book offers recommendations and examples of how to improve patient safety by changing practices, introducing organizational and technological innovations, and creating effective, patient-centered, timely, efficient, and equitable care systems, in order to spread the quality and patient safety culture among the new generation of healthcare professionals, and is intended for residents and young professionals in different clinical specialties.

Mathematics for the Clinical Laboratory

Mathematics for the Clinical Laboratory
Author: Lorraine J. Doucette
Publisher: Elsevier Health Sciences
Total Pages: 409
Release: 2015-08-19
Genre: Medical
ISBN: 0323339964
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Filled with easy-to-follow explanations and loads of examples and sample problems, Mathematics for the Clinical Laboratory, 3rd Edition is the perfect resource to help you master the clinical calculations needed for each area of the laboratory. Content is divided into three sections: a review of math and calculation basics, coverage of particular areas of the clinical laboratory (including immunohematology and microbiology), and statistical calculations. This new third edition also includes a new full-color design, additional text notes, formula summaries, and the latest procedures used in today's laboratories to ensure you are fully equipped with the mathematical understanding and application skills needed to succeed in professional practice. Examples of calculations for each different type of calculation are worked out in the chapters, step by step to show readers exactly what they're expected to learn and how to perform each type of calculation. Practice problems at the ends of each chapter act as a self-assessment tool to help readers determine what they need to review. Example problems and answers throughout the text can also be used as templates for solving laboratory calculations. Quick tips and notes throughout the text help readers understand and remember pertinent information. Answer key to the practice problems appears in the back of the book. Updated content and calculations reflect the latest procedures used in today's laboratories. Learning objectives at the beginning of each chapter provide a measurable outcome to achieve by the completing the chapter material. NEW! Summaries of important formulas are included at the ends of major sections. NEW! Full-color design creates a more accessible look and feel. NEW! Greek symbol appendix at the end of the book provides a quick place for readers to turn to when studying. NEW! Glossary at the back of the textbook includes definitions of important mathematical terms.

Laposata's Laboratory Medicine Diagnosis of Disease in Clinical Laboratory Third Edition

Laposata's Laboratory Medicine Diagnosis of Disease in Clinical Laboratory Third Edition
Author: Michael Laposata
Publisher: McGraw Hill Professional
Total Pages: 592
Release: 2019-01-04
Genre: Medical
ISBN: 1260116808
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The acclaimed full-color guide to selecting the correct laboratory test and interpreting the results –- covering ALL of clinical pathology A Doody’s Core Title for 2019! Laboratory Medicine is the most comprehensive, user-friendly, and well-illustrated guide available for learning how to order the correct laboratory test and understand the clinical significance of the results. The book features an easy-to-follow, consistent presentation for each disease discussed. Chapters begin with a brief description of the disorder followed by a discussion that includes tables detailing the laboratory evaluation of specific disorders, diagnosis, baseline tests to exclude diagnostic possibilities, and clinical indications that warrant further screening and special testing. With new, increasingly expensive and complicated tests appearing almost daily, Laboratory Medicine, Third Edition is required reading for medical students, clinical laboratory scientists, and healthcare professionals who want to keep abreast of the latest testing procedures and maximize accuracy and patient safety. Features: •48 clinical laboratory methods presented in easy-to-understand illustrations that include information on the expense and complexity of the assays •More than 200 tables and full-color algorithms that encapsulate important information and facilitate understanding •Full-color blood-smear micrographs that demonstrate common abnormal morphologies of red blood cells •Valuable learning aids in each chapter, including learning objectives, chapter outlines, and a general introduction -- and new to this edition: chapter-ending self-assessment Q&A •Logical systems-based organization that complements most textbooks •Extensive table of Clinical Laboratory Reference Values that show the conversions between U.S. and SI units for each value

Clinical Laboratory Medicine

Clinical Laboratory Medicine
Author: Kenneth D. McClatchey
Publisher: Lippincott Williams & Wilkins
Total Pages: 1732
Release: 2002
Genre: Medical
ISBN: 9780683307511
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This thoroughly updated Second Edition of Clinical Laboratory Medicine provides the most complete, current, and clinically oriented information in the field. The text features over 70 chapters--seven new to this edition, including medical laboratory ethics, point-of-care testing, bone marrow transplantation, and specimen testing--providing comprehensive coverage of contemporary laboratory medicine. Sections on molecular diagnostics, cytogenetics, and laboratory management plus the emphasis on interpretation and clinical significance of laboratory tests (why a test or series of tests is being done and what the results mean for the patient) make this a valuable resource for practicing pathologists, residents, fellows, and laboratorians. Includes over 800 illustrations, 353 in full color and 270 new to this edition. Includes a Self-Assessment and Review book.

Contemporary Practice in Clinical Chemistry

Contemporary Practice in Clinical Chemistry
Author: William Clarke
Publisher: Academic Press
Total Pages: 1070
Release: 2020-06-11
Genre: Science
ISBN: 0128158336
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Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. Includes enhanced illustration and new and revised color figures Provides improved self-assessment questions and end-of-chapter assessment questions