A System of physiologic therapeutics v.10, 1903
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Total Pages | : 512 |
Release | : 1903 |
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Author | : |
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Total Pages | : 512 |
Release | : 1903 |
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Total Pages | : 492 |
Release | : 1903 |
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Author | : Filippo Crea |
Publisher | : Springer Science & Business Media |
Total Pages | : 263 |
Release | : 2013-08-15 |
Genre | : Medical |
ISBN | : 8847053676 |
In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.
Author | : József Dombi |
Publisher | : Springer Nature |
Total Pages | : 186 |
Release | : 2021-04-28 |
Genre | : Technology & Engineering |
ISBN | : 3030722805 |
The research presented in this book shows how combining deep neural networks with a special class of fuzzy logical rules and multi-criteria decision tools can make deep neural networks more interpretable – and even, in many cases, more efficient. Fuzzy logic together with multi-criteria decision-making tools provides very powerful tools for modeling human thinking. Based on their common theoretical basis, we propose a consistent framework for modeling human thinking by using the tools of all three fields: fuzzy logic, multi-criteria decision-making, and deep learning to help reduce the black-box nature of neural models; a challenge that is of vital importance to the whole research community.
Author | : Susmita Datta |
Publisher | : Springer |
Total Pages | : 294 |
Release | : 2016-12-15 |
Genre | : Medical |
ISBN | : 3319458094 |
This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.
Author | : Janmenjoy Nayak |
Publisher | : Springer Nature |
Total Pages | : 461 |
Release | : 2021-05-29 |
Genre | : Technology & Engineering |
ISBN | : 3030719758 |
This book introduces a variety of advanced machine learning approaches covering the areas of neural networks, fuzzy logic, and hybrid intelligent systems for the determination and diagnosis of cancer. Moreover, the tactical solutions of machine learning have proved its vast range of significance and, provided novel solutions in the medical field for the diagnosis of disease. This book also explores the distinct deep learning approaches that are capable of yielding more accurate outcomes for the diagnosis of cancer. In addition to providing an overview of the emerging machine and deep learning approaches, it also enlightens an insight on how to evaluate the efficiency and appropriateness of such techniques and analysis of cancer data used in the cancer diagnosis. Therefore, this book focuses on the recent advancements in the machine learning and deep learning approaches used in the diagnosis of different types of cancer along with their research challenges and future directions for the targeted audience including scientists, experts, Ph.D. students, postdocs, and anyone interested in the subjects discussed.
Author | : Kishor Kumar Sadasivuni |
Publisher | : Springer |
Total Pages | : 383 |
Release | : 2015-01-19 |
Genre | : Technology & Engineering |
ISBN | : 3319138758 |
This book covers graphene reinforced polymers, which are useful in electronic applications, including electrically conductive thermoplastics composites, thermosets and elastomers. It systematically introduces the reader to fundamental aspects and leads over to actual applications, such as sensor fabrication, electromagnetic interference shielding, optoelectronics, superconductivity, or memory chips. The book also describes dielectric and thermal behaviour of graphene polymer composites - properties which are essential to consider for the fabrication and production of these new electronic materials. The contributions in this book critically discuss the actual questions in the development and applications of graphene polymer composites. It will thus appeal to chemists, physicists, materials scientists as well as nano technologists, who are interested in the properties of graphene polymer composites.
Author | : Gunnar Andersson |
Publisher | : |
Total Pages | : 274 |
Release | : 2008 |
Genre | : Medical |
ISBN | : |
This study measures the incidence and prevalence of musculoskeletal conditions and projects trends, presenting the latest national data illuminating the physical and economic costs. Several professional organizations concerned with musculoskeletal health and the mission of the U.S. Bone and Joint Decade collaborated to tabulate the data, to educate health care professionals, policy makers and the public.--Publisher's description.
Author | : Chittaranjan Kole |
Publisher | : Springer Nature |
Total Pages | : 340 |
Release | : 2021-08-31 |
Genre | : Science |
ISBN | : 3030758796 |
This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the biotic stresses caused by different diseases and pests that are important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in cereal crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to biotic stresses. The eight chapters each dedicated to a cereal crop in this volume elucidate on different types of biotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to biotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing biotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating biotic stress-resistant crops.
Author | : Mohammad A. Tabrizi |
Publisher | : Springer |
Total Pages | : 257 |
Release | : 2018-09-11 |
Genre | : Medical |
ISBN | : 9811304963 |
With a key focus on recent developments and advances in the field, this book provides in-depth coverage of topics fundamental to the development of targeted therapeutics. The expansion of targeted modalities in rapidly evolving therapeutic areas, such as immune-oncology, and developments with respect to combination therapies, novel technologies, and the therapeutic application of antibody-drug conjugates, are presented. Additionally, the book builds upon topics discussed in the first edition (2012) where recent innovations warrant elaboration. This, the second edition of Development of Antibody-Based Therapeutics: Translational Considerations, represents a comprehensive evaluation of progress in the field, which sits alongside the first edition to inform, in detail, professional and academic researchers, as well as graduate students.