Population Genomics of Range Expansion in the White-footed Mouse (Peromyscus Leucopus) in Southern Quebec and Evidence of Introgression from the Deer Mouse (Peromyscus Maniculatus)

Population Genomics of Range Expansion in the White-footed Mouse (Peromyscus Leucopus) in Southern Quebec and Evidence of Introgression from the Deer Mouse (Peromyscus Maniculatus)
Author: Alan Garcia-Elfring
Publisher:
Total Pages:
Release: 2017
Genre:
ISBN:

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"Processes like allele surfing and genetic bottlenecks during range expansion have genetic consequences expected to result in differentiated wave-front populations with low genetic variation and potentially introgression by a local species. The northward expansion of Peromyscus leucopus in southern Quebec provides an opportunity to test these predictions using population genomic tools. Our results show evidence of recent and post-glacial expansion. Genome-wide variation in P. leucopus indicates two putative glacial lineages are separated by the St. Lawrence River, with a more recent post-glacial divergence of populations isolated by the Richelieu River. Most regressions of genetic diversity against relative expansion distance were not significant and half contradicted expectation by showing positive trends. However, in two of three transects we documented northern populations with the lowest diversity in at least one genetic measure. Consistent with bottlenecks and allele surfing during northward expansion, we document a northern-most population having low nucleotide diversity, divergent allele frequencies, the most private alleles, as well as the lowest effective population size and heterozygosity levels that indicate outcrossing. Ancestry proportions revealed putative hybrids of P. leucopus and P. maniculatus. A formal test for gene flow confirmed secondary contact, showing that a reticulate population phylogeny between P. maniculatus and P. leucopus was a better fit to the data than a bifurcating model without gene flow. Thus, we provide the first genomic evidence of gene flow between this pair of species in natural populations. Understanding the evolutionary consequences of secondary contact is an important conservation concern as climate-induced range expansions are expected to result in new hybrid zones between closely related species, with potential consequences for emerging infectious diseases." --

Master's Theses Directories

Master's Theses Directories
Author:
Publisher:
Total Pages: 560
Release: 1991
Genre: Dissertations, Academic
ISBN:

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A Population Study of White-footed Mice (Peromyscus Leucopus) and Meadow Voles (Microtus Pennsylvanicus) in Central Kentucky

A Population Study of White-footed Mice (Peromyscus Leucopus) and Meadow Voles (Microtus Pennsylvanicus) in Central Kentucky
Author: Ryan Matthew Dunbar
Publisher:
Total Pages: 94
Release: 2006
Genre: Animal populations
ISBN:

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Habitat edges are an important ecological concept that applies to numerous organisms. Habitat edges are thought to be an area of increased abundance and diversity of animal and plant species. The increased variety and density of species at the intersection of different habitat types constitutes the basis of the "edge effect" concept. The purpose of this study was to examine the influence of edge on the seasonal densities of Microtus pennsylvanicus and Peromyscus leucopus. The hypothesis tested was that small mammal populations should be greater in edge habitats than interior habitats. Study grids were placed in three different habitat types: open field, forest, and field/forest edges. Grids were live-trapped for one week during the spring, summer, and fall to test for seasonal differences. Habitat data was taken in all habitats to test for vegetation differences. Multi-variable analysis of variance (MANOVA) was applied to the data to test for any differences between the variables (species, season, and habitat). White-footed mice made up 87% of the captures in the forested habitat and meadow voles made up 70% of the captures in the old-field habitat. No edge effect was found for either species, however, meadow voles were found in very low numbers 30 m from forested habitats as compared to 30 m from forested habitats. Most of the statistical differences in habitat data came from season and not habitat type. Neither species exhibited any significant population density differences among seasons or habitats. The habitat data taken in the old-field habitats show that percent ground cover, grass/forb height, and appearance of runaways all were important in determining where a meadow vole was captured. The habitat data taken in the forested habitats show that percent canopy cover and shrub height were important in determining where a white-footed mouse was captured, but percent ground cover and fallen log density were not important.

The Influence of Habitat and Landscape Structure on the Genetic Differentiation of the White-footed Mouse (Peromyscus Leucopus)

The Influence of Habitat and Landscape Structure on the Genetic Differentiation of the White-footed Mouse (Peromyscus Leucopus)
Author: Robby Marrotte
Publisher:
Total Pages:
Release: 2013
Genre:
ISBN:

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"The white-footed mouse (Peromyscus leucopus) is a widespread habitat generalist species abundant over a large part of the North-American continent. In the past decade, due to climate and land use change, the range of this species has expanded northwards into Canada. The black-legged tick (Ixodes scapularis), is the vector of Lyme disease which also has tracked climate change over the last few decades. This may have been further promoted by the growing presence of P. leucopus, a favored host for the tick. Therefore, aspects of the landscape that affect the movement and distribution of the white-footed mouse, will also affect the expansion of the tick, and consequently the spread of Lyme disease. In this thesis, I first reviewed published results that relied on genetic and non- genetic biological data to investigate the influence of local habitat and landscape characteristics on the movement and dispersal patterns in the white footed-mouse. Next, I evaluated the relations between breeding habitat and landscape resistance against the genetic differentiation between 11 populations in Montérégie, Québec, Canada. I was able to simultaneously measure the effect of the habitat and the landscape on the genetic differentiation of these mouse populations by utilizing numerical optimization to fit a model to previously published genetic data. I used ecological distance computed from resistance surfaces with Circuitscape to infer the effect of the landscape. Concurrently, I estimated the habitat quality of our sampling localities and correlated these to relevant habitat measurements. I found that both characteristics within and between forest patches have more of an impact on genetic differentiation than the geographical distance between the mice populations. This suggests that this species can disperse and use a wide range of habitats, in accordance with its recent rapid expansion in the region." --

Effects of Forest Fragmentation on the Abundance, Distribution, and Population Genetic Structure of White-footed Mice (Peromyscus Leucopus)

Effects of Forest Fragmentation on the Abundance, Distribution, and Population Genetic Structure of White-footed Mice (Peromyscus Leucopus)
Author: Christine Schandorsky Anderson
Publisher:
Total Pages:
Release: 2004
Genre: Fragmented landscapes
ISBN:

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Fragmentation of forests has led to the creation of forest patches that differ in size, proportion of edge habitat, and degree of isolation. Although densities of many mammalian species are positively related to patch area, there appears to be a general negative relationship between density of white-footed mice (Peromyscus leucopus) and patch area. In Chapters 2 - 5, I investigated both resource-based (i.e., vegetation characteristics) and dispersal-based (i.e., inhibited dispersal and sink) hypotheses to explain the negative density - area relationship using live-trapping data and DNA-microsatellite analyses. As an extension of how forest fragmentation may affect movements by this habitat generalist into and out of habitats, in Chapter 6 I focused on how patch isolation influences population genetic structure. Data were collected from 1999 to 2001 in 15 different patches of various sizes and degrees of isolation. I confirmed that relative abundance of P. leucopus was negatively related to forest patch area (Chapter 2). My results indicated that relative abundance of P. leucopus was positively related to structural complexity of understory vegetation and total basal area of trees, and tended to be negatively related to the species richness of trees (Chapter 2 and 3). Although I was unable to differentiate whether understory vegetation results in higher relative abundances due to food or cover, the results suggest that vegetation characteristics contribute to the negative density - area relationship. Based on live-trapping data and DNA-microsatellite analyses, I rejected both dispersal-based hypotheses to explain the effect of patch area on relative abundance of P. leucopus (Chapters 4 and 5). Within-population genetic variation was high across populations, and only 50% of individuals could be assigned to their population of capture based on multilocus genotypes, suggesting high rates of gene flow. Degree of isolation and landscape structure had a small but significant influence on population genetic structure in this species (Chapter 6). This project illustrates the habitat generalist behavior and good dispersal ability of white-footed mice, but it appears that both abiotic and biotic factors, including competition and predation, are important in explaining the effects of forest fragmentation on P. leucopus.

Public Health Significance of Urban Pests

Public Health Significance of Urban Pests
Author: Xavier Bonnefoy
Publisher: World Health Organization
Total Pages: 293
Release: 2008
Genre: Medical
ISBN: 9289071885

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The second half of the 20th century and the beginning of the 21st century witnessed important changes in ecology, climate and human behaviour that favoured the development of urban pests. Most alarmingly, urban planners now face the dramatic expansion of urban sprawl, in which city suburbs are growing into the natural habitats of ticks, rodents and other pests. Also, many city managers now erroneously assume that pest-borne diseases are relics of the past. All these changes make timely a new analysis of the direct and indirect effects of present-day urban pests on health. Such an analysis should lead to the development of strategies to manage them and reduce the risk of exposure. To this end, WHO invited international experts in various fields - pests, pest-related diseases and pest management - to provide evidence on which to base policies. These experts identified the public health risk posed by various pests and appropriate measures to prevent and control them. This book presents their conclusions and formulates policy options for all levels of decision-making to manage pests and pest-related diseases in the future. [Ed.]

Wildlife Disease Ecology

Wildlife Disease Ecology
Author: Kenneth Wilson
Publisher: Cambridge University Press
Total Pages: 693
Release: 2019-11-14
Genre: Mathematics
ISBN: 1107136563

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Introduces readers to key case studies that illustrate how theory and data can be integrated to understand wildlife disease ecology.

Pathology and Pathogenesis of Human Viral Disease

Pathology and Pathogenesis of Human Viral Disease
Author: John E. Craighead
Publisher: Academic Press
Total Pages: 466
Release: 2000-03-15
Genre: Medical
ISBN: 0080538487

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Pathology and Pathogenesis of Human Viral Disease is a comprehensive reference that examines virus-induced clinical disease of humans in the context of the responsible virus and its epidemiology. Encompassing everything from cold and flu viruses to sexually transmitted diseases, this important resource describes the cellular and tissue pathological changes attributable to infection in the context of the pathogenic mechanisms involved. The author provides a comprehensive review of the older and contemporary literature, considering both the common and much rarer complications of infection. Pathology and Pathogenesis of Human Viral Disease is written from the unique perspective of the clinical pathologist. It will help clinicians and pathologists gain a better understanding of changes that occur in viral infected cells, tissues, and organs. It will also serve as a pathology source book for virologists, internists, and pediatricians. Provides a comprehensive, worldwide perspective of viral disease pathology Bridges the fields of pathology and virology; integrating clinical disease with cell and tissue pathology Addresses topics from the perspective of the clinical pathologist Illustrates unique, viral induced pathological lesions Considers common and uncommon complications of infection

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases

Critical Needs and Gaps in Understanding Prevention, Amelioration, and Resolution of Lyme and Other Tick-Borne Diseases
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 560
Release: 2011-07-01
Genre: Medical
ISBN: 0309211093

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A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks-known as tick-borne diseases-can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases.