A Molecular Conception of Organisms and Neoplasms

A Molecular Conception of Organisms and Neoplasms
Author: T. L. Cleave
Publisher: Elsevier
Total Pages: 28
Release: 2016-02-02
Genre: Science
ISBN: 1483221547

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A Molecular Conception of Organisms and Neoplasms is a six-chapter thesis that consists of a chain of reasoning on the theory of molecular conception. This thesis contends that any organism, even if multicellular, is basically a single molecule, which is the key problem of the causation of neoplasms. After providing a unifying definition of a molecule, this book goes on discussing the concept of fundamental unicellularity of multicellular organism through protoplasmic continuity between its cells. The succeeding chapters highlight the principles of the molecular conception of organisms and neoplasms. The final chapters outline the other activities of an organism determined by the molecular conception theory, such as embryonic development, animal heat, movement, pleasure and pain, and mind. This book will be of value to biochemists and clinical chemists.

A Molecular Conception of Organisms and Neoplasms. A Theory that Any Organism is Basically a Single Chemical Molecule, Put Forward as the Key to the Problem of the Causation of Neoplasms ... Third Edition

A Molecular Conception of Organisms and Neoplasms. A Theory that Any Organism is Basically a Single Chemical Molecule, Put Forward as the Key to the Problem of the Causation of Neoplasms ... Third Edition
Author: Thomas Latimer CLEAVE
Publisher:
Total Pages: 27
Release: 1955
Genre:
ISBN:

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A Theory That Any Organism Is a Single Chemical Molecule

A Theory That Any Organism Is a Single Chemical Molecule
Author: T. L. Cleave
Publisher: Elsevier
Total Pages: 24
Release: 2013-09-11
Genre: Science
ISBN: 1483281272

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A Theory that any Organism is a Single Chemical Molecule focuses on the reactions, transformations, properties, technologies, and approaches involved in the study of molecules. The book first underscores the reasons in saying that a multicellular organism is in reality fundamentally unicellular. The text then elaborates on the molecular conception of organisms, including unicellular plant organism, multicellular plant organism, and a unicellular animal organism and a multicellular animal organism. The publication also highlights the molecular conception of neoplasms. The manuscript also takes a look at the explanation of other activities in an organism by the molecular theory. Discussions focus on embryonic development, animal heart, movement, pleasure and pain, and mind. The publication is a reliable source of data for readers interested in the structure and composition of organisms.

Molecular Biology of The Cell

Molecular Biology of The Cell
Author: Bruce Alberts
Publisher:
Total Pages: 0
Release: 2002
Genre: Cytology
ISBN: 9780815332183

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Understanding Cancer

Understanding Cancer
Author: David Tarin
Publisher: Springer Nature
Total Pages: 332
Release: 2023-02-02
Genre: Medical
ISBN: 303097393X

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This book provides a unique, wide-ranging description of the phenomenon of cancer and its pathological effects in diverse species including humans, domesticated and wild animals, invertebrates, and plants. The broad scope of information presented is used to construct radical new insights into biological self-regulation and explain their relevance to its disruption by cancerous growth and spread within the human body. Mechanisms of action of carcinogenic agents, initiation, progression, metastasis, inappropriate gene expression, dormancy, latency, regression, and reasons for susceptibility and/or resistance to cancer are all considered. Also discussed are criteria for pathological diagnosis, advances in treatment, implications for public health, and pitfalls in diagnosis and interpretation of experimental results. The book describes operational mechanisms of cancer at the levels of whole individual, organ, tissue, cell, molecular, and even atomic (quantum) scales of structural and physiological order. Evidence is assembled from all these levels of organization to show that cancer is a dynamically changing disorder and that it is an inherent and perpetual risk of multicellular composition. This provides pragmatic new biological and clinical perspectives on malignant neoplasia. The biological insight is that it is a consequence of progressing miscommunication within a cellular society. The clinical perspective is realistic but optimistic in reasoning that, although cancer can never be completely eradicated from human life, because it is a disorder of our intrinsic biological constitution, it can be controlled and ameliorated and even cured in a proportion of individuals. The text is profusely illustrated with over 300 macroscopic and microscopic pictures. It will stimulate curiosity and interest specialists, as well as beginners, in many scientific disciplines and provides copious references to the medical and scientific literature supporting its conclusions. Readers from fields as diverse as medicine, pathology, veterinary sciences, cell biology, molecular biology, developmental biology, and epidemiology will find the information the book contains thought-provoking, interesting, and useful. Additionally, specialists in occupational and environmental health and legal experts focusing on exposure to carcinogenic materials and pollution will find the contents valuable and informative.

From Molecules to Organisms

From Molecules to Organisms
Author: Alexander Poletaev
Publisher:
Total Pages: 342
Release: 2020
Genre: Biology
ISBN: 9781536175516

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What is a Life? How did it appear? What principles underlie its functioning? Similar questions have accompanied man since birth. People of all ages have tried to answer these questions on the basis of the maturity of the available knowledge and techniques. This is why the theory of evolution preserves, even in modern science, a central role, embracing all the spheres of biology, physics and medicine. The modern concept of evolution is extremely simple; nevertheless, many scientists still show great difficulties in incorporating and integrating this concept into their work. One of the main errors is the assumption that the different species developed along an "evolutionary scale", from bacteria to animals, more or less complex, up to man, which would therefore represent the apex of evolution. Most people, who wish to and are living a long life remaining active and cheerful until old age, are increasingly seeking doctors' help. What is health? Some believe that it is the absence of diseases and physical defects. For some, it is a state of physical, mental and social well-being. However, despite the different definitions of this concept, everyone agrees that health is a leading factor in determining the quality of our lives. Health is influenced by many factors. Some of them improve health others worsen it (risk factors). Some experts have compiled a list of the main factors affecting health and given an indicative assessment of the degree of importance of each of them. This includes lifestyle, environmental influences, quality of medical care and heredity. A physician who regularly observes a given individual has to face challenges that modern medicine hasn't sufficiently researched and developed, assess the individual risk of developing a disease, identify early markers of change leading to disease development and individually select the corrective actions. It should be noted that one of the most important conditions for long-term preservation of health is the development of methods from the earliest possible diagnosis of diseases at the preclinical stage. This book combines the experience of clinical and laboratory research as well as some basic philosophy ideas of a group of scientists who, starting from an individual point of view, were able to synthesize and make available to other colleagues a new way of view of human organism and explaining the events that can trigger pathological conditions, including cancer, autism, diabetes and other chronical diseases.

Cancer Evolution

Cancer Evolution
Author: Charles Swanton
Publisher: Perspectives Cshl
Total Pages: 350
Release: 2017
Genre: Medical
ISBN: 9781621821434

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Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.

Molecular Biology for Oncologists

Molecular Biology for Oncologists
Author: Trevor McMillan
Publisher: Springer
Total Pages: 353
Release: 1996-01-01
Genre: Medical
ISBN: 9780412712708

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The pathophysiology, cell proliferation kinetics and metastasis of cancers and their responses to the currently employed therapies are increasingly being understood in terms of their genetic control mechanisms. Parallel genetic investigations are being aggressively pursued for normal tissue systems. The resultant greatly enhanced understanding is leading to clinically useful predictors of prognosis and the beginnings of new therapeutic strategies so as to augment the differential effect on tumour and normal tissues. This includes not only manoeuvres which deploy the currently available treatment methods with greater effect, but also the intro duction into the clinic of conceptually different treatment strategies, with the potential of great positive impact. Development in the field of basic genetics of cancer biology, cell cycle control, angiogenesis, immunology, etc. have been extraordinarily rapid with exceptional importance to medicine. This area has attracted some of the keenest intellects and greatest enthusiasm in biology and medicine. To illustrate the vigour and the growth rate of the research activity in this area, note that the numbers of journal articles published with the words gene and cancer (carcinoma, sarcoma, neoplasm, tumour) in the title or abstract for 1975 was 14 and for 1995 was 14 593. This number has increased dramatically over the past two decades. The entire field of oncology (clinical and laboratory) has, likewise, been growing at a remarkable pace.