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| Author | : J. P. Lenney |
| Publisher | : |
| Total Pages | : |
| Release | : 1995 |
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| Author | : Aradhana Dutta |
| Publisher | : Springer |
| Total Pages | : 194 |
| Release | : 2016-08-30 |
| Genre | : Technology & Engineering |
| ISBN | : 3319351400 |
This book concentrates on the design and development of integrated optic waveguide sensors using silicon based materials. The implementation of such system as a tool for detecting adulteration in petroleum based products as well as its use for detection of glucose level in diabetes are highlighted. The first chapters are dedicated to the development of the theoretical model while the final chapters are focused on the different applications of such sensors. It gives the readers the full background in the field of sensors, reasons for using silicon oxynitride as a potential waveguide material as well as its fabrication processes and possible uses.
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| Release | : 2009 |
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An assay element is described including recognition ligands adapted for binding to carcinoembryonic antigen (CEA) bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of CEA is described including injecting a possible CEA-containing sample into a sensor cell including the assay element, maintaining the sample within the sensor cell for time sufficient for binding to occur between CEA present within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.
| Author | : |
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| Release | : 2009 |
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An assay element is described including recognition ligands bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of a biological target is described including injecting a biological target-containing sample into a sensor cell including the assay element, with the recognition ligands adapted for binding to selected biological targets, maintaining the sample within the sensor cell for time sufficient for binding to occur between selected biological targets within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting the fluorescent-label in any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.
| Author | : Xuming Zhang |
| Publisher | : MDPI |
| Total Pages | : 150 |
| Release | : 2018-08-15 |
| Genre | : Electronic books |
| ISBN | : 3038970956 |
This book is a printed edition of the Special Issue "Advances in Optofluidics" that was published in Micromachines
| Author | : Jens Kremeskötter |
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| Release | : 1995 |
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| Author | : Alexander P. Demchenko |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 606 |
| Release | : 2008-12-21 |
| Genre | : Medical |
| ISBN | : 140209003X |
Fluorescence sensing is a rapidly developing field of research and technology. Its target is nearly the whole world of natural and synthetic compounds being detected in different media including living bodies. The application area range from control of industrial processes to environment monitoring and clinical diagnostics. Among different detection methods fluorescence techniques are distinguished by ultimate sensitivity, high temporal and spatial resolution and versatility that allows not only remote detection of different targets but their imaging within the living cells. The basic mechanism of sensing is the transmission of the signal produced by molecular interaction with the target to fluorescent molecules, nanoparticles and nanocomposites with the detection by devices based on modern electronics and optics. In this interdisciplinary field of research and development the book is primarily intended to be a guide for students and young researchers. It is also addressed to professionals involved in active research and product development serving as a reference for the recent achievements. The users of these products will find description of principles that could allow proper selection of sensors for particular needs. Making a strong link between education, research and product development, this book discusses future directions.
| Author | : Heinz Raether |
| Publisher | : Springer |
| Total Pages | : 143 |
| Release | : 2006-04-11 |
| Genre | : Science |
| ISBN | : 3540474412 |
The book reviews the properties of surface plasmons that depict electromagnetic surface waves or surface plasma polaritons. Their propagation on smooth and corrugated surfaces (with rough or grating profiles) is considered. In the latter case, the corrugations can cause strong coupling of the surface plasmons with photons leading to resonances with a strong enhancement of the electromagnetic field in the surface. Coupling and field enhancement are the most prominent phenomena on corrugated surfaces and lead to numerous important applications. Attention has been focused on the explanation of the physics. To keep the text readable, sophisticated calculations have been avoided, and instead various applications dealing with enhanced light emission, nonlinear optics, SERS, and other cases of interest are discussed.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 209 |
| Release | : 2005-12-11 |
| Genre | : Political Science |
| ISBN | : 030909576X |
Over the last ten years, there has been growing concern about potential biological attacks on the nation's population and its military facilities. It is now possible to detect such attacks quickly enough to permit treatment of potential victims prior to the onset of symptoms. The capability to "detect to warn", that is in time to take action to minimize human exposure, however, is still lacking. To help achieve such a capability, the Defense Threat Reduction Agency (DTRA) asked the National Research Council (NRC) to assess the development path for "detect to warn" sensors systems. This report presents the results of this assessment including analysis of scenarios for protecting facilities, sensor requirements, and detection technologies and systems. Findings and recommendations are provided for the most probable path to achieve a detect-to-warn capability and potential technological breakthroughs that could accelerate its attainment.
