The Use of Drugs in Food Animals

The Use of Drugs in Food Animals
Author: National Research Council
Publisher: National Academies Press
Total Pages: 276
Release: 1999-01-12
Genre: Medical
ISBN: 0309175771

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The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.

Veterinary Drug Residues

Veterinary Drug Residues
Author: R. J. Heitzman
Publisher: Wiley-Blackwell
Total Pages: 512
Release: 1994
Genre: Medical
ISBN: 9780632037865

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The purpose of this second edition is to bring together the current rapid developments and activities in residues of veterinary drugs within the European Community. The EEC legislation is summarised. There is information on the Reference Laboratories, the Maximum Residues Limits (MRL) and the criteria for the methods to be used for routine analysis of residues by Member States and third countries wishing to export meat to the EC. The current state of examination of residues practised and the analytical methods used in Member States is described in detail. There is a section on quality assurance in the laboratory and also supporting information on residues and chemical/physical data of the most important veterinary drugs

Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin

Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin
Author: V.K. Agarwal
Publisher: Springer Science & Business Media
Total Pages: 260
Release: 2012-12-06
Genre: Medical
ISBN: 1461533562

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In the last three decades. use of antibiotics/drugs in animal husbandry programs has grown tremendously. Antibiotics/drugs are used therapeutically to cure diseases. and subtherapeutically to control the outbreak of diseases, improve feed efficiency and promote growth. The presence of antibiotic/drug residues in food products of animal origin. i.e •• meat, poultry and milk, can be a potential health hazard to consumers. Significant research is being done to develop new methods or to improve on existing methods to confirm and quantitatively determine the antibiotic/drug residues in meat, poultry and milk. This book covers recent development and application of various analytical techniques for the determination of antibiotic/drug residues in food products of animal origin. I thank the authors for their time and efforts in preparing the manuscripts and "all the reviewers for reviewing the manuscripts. I also thank to the Division of Agricultural and Food Chemistry of the American Chemical Society for sponsoring the symposium and Hewlett Packard, Palo Alto, CA, Perkin Elmer Corp., Norwalk, CT, Millipore Corporation, Milford, MA, and Kraft General Foods, Glenview, IL, for their generous financial support for the symposium. Vipin K. Agarwal New Haven, CT v CONTENTS Importance of Laboratory Validations and Accurate Descriptions of Analytical Procedures for Drug Residues in Foods ................. .

Evaluation of Certain Veterinary Drug Residues in Food

Evaluation of Certain Veterinary Drug Residues in Food
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting
Publisher: World Health Organization
Total Pages: 144
Release: 2009
Genre: Business & Economics
ISBN: 9241209542

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This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including a hypothesis-driven decision tree approach for the safety evaluation of residues of veterinary drugs; comments on the Committee for Veterinary Products for Medicinal Use reflection paper on the new approach developed by JECFA for exposure and maximum residue limit (MRL) assessment of residues; residues of veterinary drugs in honey and possible approaches to derive MRLs for this commodity; comments on a paper entitled "Risk-assessment policies: Differences among jurisdictions"; and the use of no-observed-effect level (NOEL) and no-observed-adverse-effect level (NOAEL) in JECFA assessments. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (avilamycin, tilmicosin, tylosin), one authentic (triclabendazole), one production aid (melengestrol acetate), two antimicrobial agents and production aids (monesin and narasin), a glucocorticosteroid (dexamethasone) and an antimicrobial agent ands contaminant (malachite green). Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes (ADI's) and proposed MRL's.

Residues of Some Veterinary Drugs in Animals and Foods

Residues of Some Veterinary Drugs in Animals and Foods
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting
Publisher: Food & Agriculture Org.
Total Pages: 108
Release: 1998
Genre: Business & Economics
ISBN: 9789251041284

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This document is one of the three publications prepared by the forty-eighth session of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Geneva, February 1997, and dedicated exclusively to the evaluation of, veterinary drug residues in food. The report of the meeting will be published in the WHO Technical Report Series, and the toxicological monographs as No. 39 in the WHO Food Additives Series. Residue monographs in this document provide information on chemical identity, properties, use, pharmacokinetics, metabolism, tissue residue depletion of, and analytical methods for substances indicated on the cover. This publication is meant for regulatory authorities, veterinary drug researchers and any other concerned persons who wish to gain information and insights into the needs and problems involved in establishing maximum limits for veterinary drug residues in food.

Evaluation of Certain Veterinary Drug Residues in Food

Evaluation of Certain Veterinary Drug Residues in Food
Author: Joint FAO/WHO Expert Committee on Food Additives
Publisher: World Health Organization
Total Pages: 104
Release: 2001-05
Genre: Business & Economics
ISBN: 9241209003

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This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of JECFA, including compounds without an ADI or MRL; recommendations on principles and methods in derivation of MRLs, including a new procedure for estimating chronic dietary intakes; the use of a spreadsheet-based procedure for the statistical evaluati.

Antimicrobial Therapy in Veterinary Medicine

Antimicrobial Therapy in Veterinary Medicine
Author: Steeve Giguère
Publisher: John Wiley & Sons
Total Pages: 49
Release: 2013-07-25
Genre: Medical
ISBN: 111867507X

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The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy. Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.

Veterinary Drug Residues

Veterinary Drug Residues
Author: William Alden Moats
Publisher:
Total Pages: 208
Release: 1996
Genre: Medical
ISBN:

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Presents both the real and perceived risks of residues associated with veterinary drugs. Provides general approaches to surveillance of residues, problems encountered when testing for residues, and some recent advances in methods for measurement of residues of various types of drugs. Includes discussions of immunochemical approaches to residue analysis, applications of milk screening tests to detecting residues in tissues, chromatographic approaches to the determination of a variety of drug residues, and interfacing chromatographic procedures with screening tests.

Evaluation of Certain Veterinary Drug Residues in Food

Evaluation of Certain Veterinary Drug Residues in Food
Author: Joint FAO/WHO Expert Committee on Food Additives. Meeting
Publisher: World Health Organization
Total Pages: 89
Release: 2006
Genre: Business & Economics
ISBN: 9241209399

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This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of JECFA, including compounds without an ADI or MRL; recommendations on principles and methods in derivation of MRLs, including a new procedure for estimating chronic dietary intakes; the use of a spreadsheet-based procedure for the statistical evaluation of residue depletion data; a revised approach for the derivation of microbiological ADIs; and the Committee's review of and comments on documents provided by the Codex Committee on Residues of Veterinary Drugs. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (colistin, erythromycin, flumequine), two production aids (melengestrol acetate, ractopamine hydrochloride, an insecticide (trichlorfon (metrifonate)), and an anthelminthic (triclabendazole). In addition, the attempt by the Committee to use tylosin as an example to investigate if evaluations are possible based on published data in the absence of data submissions from sponsors is described. Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes and proposed maximum residue limits.

Strategies for Reducing Drug and Chemical Residues in Food Animals

Strategies for Reducing Drug and Chemical Residues in Food Animals
Author: Ronald E. Baynes
Publisher: John Wiley & Sons
Total Pages: 340
Release: 2014-09-15
Genre: Science
ISBN: 0470247525

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Highlighting international approaches; the book details strategies to minimize contamination, residue monitoring programs, and classes of drugs and chemicals that pose contaminant risk in livestock. Focuses attention on drug and chemical residues in edible animal products Covers novel computational, statistical, and mathematical strategies for dealing with chemical exposures in food animals Details major drug classes used in food animal production and their residue risks Highlights efforts at harmonizing and the differences among areas like US, EU, Canada, Australia, South America, China, and Asia, where the issue of chemical exposures has significant impact on livestock products Ties veterinary clinical practice and the use of these drugs in food animals with regulatory standards and mitigation practices