Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation

Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation
Author: Xiao-Feng Wu
Publisher: John Wiley & Sons
Total Pages: 596
Release: 2016-03-07
Genre: Technology & Engineering
ISBN: 3527338888

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Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.

Advances in Transition-Metal Mediated Heterocyclic Synthesis

Advances in Transition-Metal Mediated Heterocyclic Synthesis
Author: Daniel Sole
Publisher: Academic Press
Total Pages: 368
Release: 2018-05-17
Genre: Science
ISBN: 0128116528

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Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction). Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co). Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, this book is a valuable resource not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals. Helpfully organized by transformation type to stimulate the search for new synthetic processes Completely illustrated and written by global experts Includes thoughtfully selected strategies chosen by the editors to exemplify the state-of-the-art of the subject, including transition-metal reactions involving unsaturated systems, organopalladium chemistry, and metal-catalyzed C-H activation

Heterocycles from Double-Functionalized Arenes

Heterocycles from Double-Functionalized Arenes
Author: Xiao-Feng Wu
Publisher: Royal Society of Chemistry
Total Pages: 315
Release: 2015
Genre: Science
ISBN: 1782621369

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An introduction to transition metal catalyzed coupling reactions of double-functionalized arenes in heterocycle synthesis.

Transition Metal Catalyzed Furans Synthesis

Transition Metal Catalyzed Furans Synthesis
Author: Xiao-Feng Wu
Publisher: Elsevier
Total Pages: 117
Release: 2015-09-08
Genre: Technology & Engineering
ISBN: 0128040726

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Transition Metal Catalyzed Furans Synthesis provides an overview of Furans, describing properties of these heterocycle compounds and covering traditional synthetic procedures for them. This book then explores catalyzed procedures for Furans synthesis in greater detail and depth then is currently available in published Reviews. Finally, this useful short work discusses natural products and bio-active compounds containing Furans, information of particular interest for their applications to medicinal and pharmaceutical chemistry. The short series Transition Metal Catalyzed Heterocycles Synthesis Series, authored by Xiao-Feng Wu, summarizes recent achievements on heterocycles synthesis with transition metal as the catalysts, with each volume dedicated to one heterocycle compound. Brief, focused review of this active research area, Furans synthesis via transition metal catalysis Useful coverage of furans properties and procedures, as well as relevant Furan-containing natural products First volume in short work series, "Transition Metal-Catalyzed Heterocycles Synthesis"

Heterocycles from Transition Metal Catalysis

Heterocycles from Transition Metal Catalysis
Author: András Kotschy
Publisher: Springer Science & Business Media
Total Pages: 224
Release: 2005-09-30
Genre: Science
ISBN: 9781402036248

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"Heterocycles from Transition Metal Catalysis: Formation and Functionalization" provides a concise summary of the prominent role of late transition metal (palladium, nickel, copper) catalysed processes in the synthesis and functionalization of heterocyclic systems. It gives an introduction to catalytic transformations, an overview of the most important reaction types, and presents synthetically useful catalytic processes classified by the target system and the type of transformation. The book provides a representative selection of transition metal catalysed reactions transformations that are relevant in heterocyclic chemistry. In this way, the authors present a useful resource for members of the academic community looking for a textbook as well as industrial chemists in search of a reference book. This book will be an invaluable resource for synthetic chemists, medicinal chemists, and those more generally interested in applied catalysis.

Metals and Non-metals

Metals and Non-metals
Author: Navjeet Kaur
Publisher: CRC Press
Total Pages: 404
Release: 2020-01-28
Genre: Science
ISBN: 1000733416

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Design of new processes that avoid the use of toxic reagents has been the focus of intense research of late. Catalysis by metals and non-metals offers diverse opportunities for the development of new organic reactions with promising range of selectivities—chemoselectivity, regioselectivity, diastereoselectivity, and enantioselectivity. Furthermore, these transformations frequently occur under mild conditions, tolerate a broad array of functional groups, and proceed with high stereoselectivity. The area of catalysis is sometimes referred to as a ‘foundational pillar’ of green chemistry. Catalytic reactions often reduce energy requirements and decrease separations because of increased selectivity; they are also capable of permitting the use of renewable feedstocks of less toxic reagents or minimizing the quantities of reagents needed. New catalytic organic synthesis methodologies have, thus, offered several possibilities for considerable improvement in the eco-compatibility of fine chemical production. Hence, these catalytic methodologies have emerged as powerful tools for the efficient and chemoselective synthesis of heterocyclic molecules. Key Features: Presents the synthesis of different five-membered heterocycles. Contains the most up-to-date information in this fast-moving field. Covers novel catalytic approaches used in the study and application of catalysts in synthetic organic reactions. Presents new methodologies for the synthesis of heterocycles.

Transition Metal Catalyzed Carbonylative Synthesis of Heterocycles

Transition Metal Catalyzed Carbonylative Synthesis of Heterocycles
Author: Xiao-Feng Wu
Publisher: Springer
Total Pages: 176
Release: 2015-12-14
Genre: Science
ISBN: 3319249630

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The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.