Species Specificity in Peptide Elongation
Author | : Robert Kovelman |
Publisher | : |
Total Pages | : 70 |
Release | : 1970 |
Genre | : |
ISBN | : |
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Author | : Robert Kovelman |
Publisher | : |
Total Pages | : 70 |
Release | : 1970 |
Genre | : |
ISBN | : |
Author | : Bruce Alberts |
Publisher | : |
Total Pages | : 0 |
Release | : 2002 |
Genre | : Cytology |
ISBN | : 9780815332183 |
Author | : Marina V. Rodnina |
Publisher | : Springer Science & Business Media |
Total Pages | : 428 |
Release | : 2011-12-10 |
Genre | : Medical |
ISBN | : 3709102154 |
The ribosome is a macromolecular machine that synthesizes proteins with a high degree of speed and accuracy. Our present understanding of its structure, function and dynamics is the result of six decades of research. This book collects over 40 articles based on the talks presented at the 2010 Ribosome Meeting, held in Orvieto, Italy, covering all facets of the structure and function of the ribosome. New high-resolution crystal structures of functional ribosome complexes and cryo-EM structures of translating ribosomes are presented, while partial reactions of translation are examined in structural and mechanistic detail, featuring translocation as a most dynamic process. Mechanisms of initiation, both in bacterial and eukaryotic systems, translation termination, and novel details of the functions of the respective factors are described. Structure and interactions of the nascent peptide within, and emerging from, the ribosomal peptide exit tunnel are addressed in several articles. Structural and single-molecule studies reveal a picture of the ribosome exhibiting the energy landscape of a processive Brownian machine. The collection provides up-to-date reviews which will serve as a source of essential information for years to come.
Author | : Herbert Weissbach |
Publisher | : Elsevier |
Total Pages | : 739 |
Release | : 2012-12-02 |
Genre | : Science |
ISBN | : 0323141706 |
Molecular Mechanisms of Protein Biosynthesis is a collection of papers dealing with cell-free systems at the molecular level, including transfer RNA; the initiation, elongation, and termination processes; ribosome structure and function; mRNA translation; and DNA-directed in vitro protein synthesis. A couple of papers review tRNA, aminoacyl-tRNA synthetases, and aspects of ribosome structure. One paper discusses affinity labeling in the study of binding and catalytic sites of large complex and heterogeneous systems such as the ribosome. The investigator should be aware of the chemically reactive or photoactivatible analogue reacting specifically with one or more ribosomal components. This reaction should be determined if it is dependent on the correct binding of the affinity label at the functional site. Another paper describes the series of reactions in protein synthesis as the process by which the ribosome moves relative to the messenger RNA. Other papers discuss messenger RNA and its translation, DNA-dependent cell-free protein synthesis, as well as the genetics of the translational apparatus. The collection will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.
Author | : Lisa Bartee |
Publisher | : |
Total Pages | : |
Release | : 2017 |
Genre | : |
ISBN | : 9781636350417 |
The Principles of Biology sequence (BI 211, 212 and 213) introduces biology as a scientific discipline for students planning to major in biology and other science disciplines. Laboratories and classroom activities introduce techniques used to study biological processes and provide opportunities for students to develop their ability to conduct research.
Author | : Heinz Bielka |
Publisher | : Walter de Gruyter GmbH & Co KG |
Total Pages | : 340 |
Release | : 1982-12-31 |
Genre | : Science |
ISBN | : 3112729757 |
No detailed description available for "The Eukaryotic Ribosome".
Author | : Antonius M. VanDongen |
Publisher | : CRC Press |
Total Pages | : 368 |
Release | : 2008-10-29 |
Genre | : Medical |
ISBN | : 142004415X |
The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written
Author | : Gregg B. Fields |
Publisher | : Academic Press |
Total Pages | : 828 |
Release | : 1997-10-21 |
Genre | : Medical |
ISBN | : |
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volumehas been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 275 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchers in all fields of life sciences. Key Features * Solid-phase peptide synthesis * Applications of peptides for structural and biological studies * Characterization of synthetic peptides
Author | : |
Publisher | : |
Total Pages | : 850 |
Release | : 1973 |
Genre | : Drugs |
ISBN | : |
Author | : Ajit Varki |
Publisher | : CSHL Press |
Total Pages | : 694 |
Release | : 1999 |
Genre | : Medical |
ISBN | : 9780879696818 |
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.