This book is the most comprehensive (and possibly the first) manual on ‘Rhino-Orbito-Cerebral Mucormycosis (ROCM) that covers mucormycosis of the nose extending to sinuses, orbit, and brain, all in. This volume covers the surge of cases during the COVID-19 pandemic, early identification and causative factors, microbiology, pathology and radiology, and the clinical presentation. Notes on surgical approaches, extent, and techniques of debridement, number of sittings, antifungal therapy, complications, and their management equip readers to manage these cases confidently. Detailed descriptions of ROCM surgery accompanied by nearly 500 photographs and anatomical drawings help support diagnostic and surgical decision-making. Also included is information on various specifications of MRI that help in achieving a perfect surgical clearance. The book includes chapters on debates on salvaging the orbit in ROCM, various situations, their management, the extent of resection, antifungal dosage and duration, prognostication of the patient, and postoperative care. The book assists surgeons in gaining the skills to perform endoscopic clearance of difficult areas like pterygoplataine fossa, infratemporal fossa, pterygoid plates, and the lacrimal drainage system, which offers significant advantages in terms of avoiding postoperative morbidity as compared to an external route. Since the external route is required in the most extensive form of the disease, the book has also covered it extensively. This book is an indispensable resource for otorhinolaryngologists, ophthalmic surgeons, ophthalmic plastic surgeons, physicians, microbiologists, pathologists, radiologists, neurosurgeons, faciomaxillary surgeons and junior and senior consultants optometrists and students.