Parasite Antigens, Parasite Genes
Author | : R. M. Maizels |
Publisher | : CUP Archive |
Total Pages | : 246 |
Release | : 1991 |
Genre | : Science |
ISBN | : 9780521419277 |
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Enzymes; 8.
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Author | : R. M. Maizels |
Publisher | : CUP Archive |
Total Pages | : 246 |
Release | : 1991 |
Genre | : Science |
ISBN | : 9780521419277 |
Enzymes; 8.
Author | : Steven A. Frank |
Publisher | : Princeton University Press |
Total Pages | : 364 |
Release | : 2002-07-21 |
Genre | : Medical |
ISBN | : 9780691095950 |
Publisher Description
Author | : |
Publisher | : ILRI (aka ILCA and ILRAD) |
Total Pages | : 56 |
Release | : |
Genre | : |
ISBN | : |
Author | : Derek Wakelin |
Publisher | : Cambridge University Press |
Total Pages | : 226 |
Release | : 1996-08-13 |
Genre | : Medical |
ISBN | : 9780521436359 |
Parasites cause many important diseases in humans and domestic animals, malaria being an example. Parasites have evolved to exploit hosts' bodies whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary 'arms-races' in which the immune system plays a key role. Modern research in immunoparasitology is directed towards understanding and exploiting the capacity to develop effective anti-parasite immunity. By concentrating on selected infections where research has made significant progress, Immunity to Parasites provides a clear account of how host immune responses operate and how parasites can evade immunity. The experimental basis of this research is emphasised throughout. This completely updated second edition includes an expanded section on anti-parasite vaccines. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and provides introductory sections on these topics to lead the reader into the later chapters.
Author | : D. Wakelin |
Publisher | : Cambridge University Press |
Total Pages | : 96 |
Release | : 1996 |
Genre | : Medical |
ISBN | : 9780521589369 |
This collection of articles, edited by D. Wakelin and D. Walliker include: Genetic variability in parasites and host-parasite interactions; Host genetics and infectious disease; T cell and cytokine basis of host variability in response to intestinal nematode infections; The role of MHC- and non-MHC-associated genes in determining the human immune response to malaria antigens; Influence of host and parasite genotypes on immunological control of Theileria parasites; Genetic susceptibility to leishmanial infections: studies in mice and man; Genetic susceptibility to malaria and other infectious diseases: from MHC to the whole genome. This volume is the specially commissioned supplement to the journal Parasitology, volume 112.
Author | : Institute of Medicine |
Publisher | : National Academies Press |
Total Pages | : 312 |
Release | : 1991-02-01 |
Genre | : Medical |
ISBN | : 9780309045278 |
Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Author | : Terry W. Pearson |
Publisher | : Marcel Dekker |
Total Pages | : 440 |
Release | : 1986 |
Genre | : Antigens |
ISBN | : |
Author | : Malcolm W. Kennedy |
Publisher | : CRC Press |
Total Pages | : 264 |
Release | : 1991-07-01 |
Genre | : Science |
ISBN | : 9780850667721 |
A review of current knowledge of nematode parasites which cause widespread mortality and disability in both man and animal, resulting in major economic and clinical implications and of the molecular techniques which are now being used to understand immunological mechanisms.
Author | : John Marchalonis |
Publisher | : Springer Science & Business Media |
Total Pages | : 512 |
Release | : 2012-12-06 |
Genre | : Medical |
ISBN | : 1468445715 |
The phenomena involved in infections of man and domestic animals with metazoan or protozoan parasites present formidable practical problems as well as a theoretical challenge to immunologists, molecular biologists, and evolu tionary biologists. With respect to the public health and economic problems, malaria, for example, remains a major health problem with approximately 200 million people being infected yearly and, on the basis of World Health Organiza tion estimates, more than 1 million children die each year of malaria infections (Chapter 4). This volume addresses state-of-the-art immunologic approaches to the development of vaccines for parasitic diseases (Chapter 9) and analyses of studies bearing on the antigenic characterization of protozoan and metazoan parasites (Chapters 4, 5, and 7), on investigations of the role of precise mecha nisms underlying natural resistance or non permissiveness of the host to parasitic infections (Chapters 1, 2, and 12), on induced mechanisms including the genera tion of parasite-specific T-cell lines and clones (Chapter 6), and on the generation of monoclonal antibodies (Chapters 4 and 5) to parasite antigens of distinct de velopmental stages. Great progress has been made in characterizing parasite antigens capable of inducing a protective response in the vaccinated host; further progress in this area strongly depends on biochemistry and molecular biology with the long-term goal of synthesizing such antigens chemically or producing them by means of recombinant DNA technology (Chapter 4).
Author | : L.H.T. Van Der Ploeg |
Publisher | : Elsevier |
Total Pages | : 332 |
Release | : 2012-12-02 |
Genre | : Medical |
ISBN | : 0323155669 |
Immune Recognition and Evasion: Molecular Aspects of Host-Parasite Interaction reviews recent advances in understanding the genetic basis of host-parasite interactions, with emphasis on antigenic epitopes, the genetics of parasites, the molecular mechanisms of immune recognition and evasion, and the way that cytokines and hormones act on host-parasite interactions. Organized into four parts encompassing 25 chapters, this volume begins with an overview of the genomic organization of the T cell receptor genes and the contribution of non-B DNA structures to switch recombination in immunoglobulin genes. It then discusses signal transduction by class II molecules encoded by the major histocompatibility complex la and the biological consequences of this process; allelic polymorphism of HLA class II antigens and its connection to the molecular basis of autoimmunity; mimicry between HLAB27 and bacteria; and genetic control of susceptibility to helminth infection. The reader is also introduced to recognition of protein antigens by antibodies; recognition of influenza antigens by class I-restricted cytotoxic T lymphocytes; the biochemical basis of cachexia of infection; mechanisms of antigenic variation in Plasmodium; and rational design of trypanocidal drugs. Geneticists and molecular biologists will gain valuable information from this book.