In this issue of Primary Care: Clinics in Office Practice, guest editor Dr. David O’Gurek brings his considerable expertise to the topic of Chronic Pain Management. Top experts in the field cover this timely topic in depth, including non-pharmacologic and rehabilitative strategies to address chronic pain and management of chronic pain in patients with substance use disorder. Contains 12 practice-oriented topics including comprehensive evaluation for chronic pain; pharmacologic management of chronic pain; trauma and behavioral health care for patients with chronic pain; the use of medical marijuana for chronic pain; ethical challenges in chronic pain management; and more. Provides in-depth clinical reviews on chronic pain management, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.