Nanobiotechnology in Neurodegenerative Diseases

Nanobiotechnology in Neurodegenerative Diseases
Author: Mahendra Rai
Publisher: Springer Nature
Total Pages: 403
Release: 2019-12-02
Genre: Medical
ISBN: 3030309304

Download Nanobiotechnology in Neurodegenerative Diseases Book in PDF, Epub and Kindle

This book focuses on neurodegenerative diseases which have become a major threat to human health. Neurodegenerative diseases are age related disorders and have become increasingly prevalent in the elderly population in recent years. Hence, there is an urgent need to study and develop new strategies and alternative methods for the treatment of neurodegenerative diseases. This book showcases the promises that nanobiotechnology brings in research, diagnosis, and treatment of neurodegenerative diseases. It is very beneficial for varied group of readers including nanotechnologists, biotechnologists, pharmacists, medical professionals, bioengineers, biochemists and researchers working in this field. Nanobiotechnology in Neurodegenerative Diseases include various chapters including neurodegeneration and neurodegenerative diseases, nanotechnology for the rescue of neurodegenerative diseases, promising potential of nanomaterials for diagnosis and therapy of neurodegenerative diseases, nanotechnology mediated nose-to-brain drug delivery, and formulation and characterization of intranasal nanoparticles of antiretroviral drugs.

Nanomedical Drug Delivery for Neurodegenerative Diseases

Nanomedical Drug Delivery for Neurodegenerative Diseases
Author: Awesh K. Yadav
Publisher: Academic Press
Total Pages: 284
Release: 2022-03-10
Genre: Medical
ISBN: 0323898017

Download Nanomedical Drug Delivery for Neurodegenerative Diseases Book in PDF, Epub and Kindle

Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases. Includes design, synthesis and applications of drug delivery systems Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems Details how nanocarrier-based delivery is useful to improve efficacy and cure

Nanocarriers in Neurodegenerative Disorders

Nanocarriers in Neurodegenerative Disorders
Author: Wael Mohamed
Publisher: CRC Press
Total Pages: 366
Release: 2024-09-30
Genre: Science
ISBN: 1040105181

Download Nanocarriers in Neurodegenerative Disorders Book in PDF, Epub and Kindle

Due to the lack of secure, efficient, and patient-friendly therapies for neurodegenerative disorders, there is a rising demand for innovative approaches. Despite the limited number of nanocarriers approved for human use, they have demonstrated significant potential in preclinical and, in some instances, clinical trials. In alignment with this objective, the chapters of the book are structured to offer a comprehensive overview of recent advancements in medication and dosage form development, specifically emphasizing the nanoparticulate system for targeting the brain. This book aims to furnish readers with a thorough understanding of the clinical application of nanocarrier systems for treating neurodegenerative disorders, encompassing the latest developments, challenges, safety concerns, toxicity issues, regulatory considerations, prospects, and limitations. Individuals in academia, the scientific community, business, and education seeking a more effective approach to target the brain will find valuable insights in this resource. Key Features Provides a comparative perspective of various nanocarrier systems, therefore facilitating the researcher's selection of appropriate nanoparticulate carriers Highlights the related restrictions of brain delivery and current available medicines Includes information on the advantages and disadvantages of various biomaterials utilized in the development of nanocarriers for brain targeting Emphasizes distinct facets of surface functionalization according to the brain area of interest Presents the current advances, preclinical and clinical development, and the future potential of multiple brain-targeting technologies

Nanoarchitectonics for Brain Drug Delivery

Nanoarchitectonics for Brain Drug Delivery
Author: Anurag Kumar Singh
Publisher: CRC Press
Total Pages: 381
Release: 2024-02-22
Genre: Technology & Engineering
ISBN: 1003851843

Download Nanoarchitectonics for Brain Drug Delivery Book in PDF, Epub and Kindle

This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain delivery Provides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancer Discusses key advances in the development of polymer nanoparticles for drug delivery to the CNS Reviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disorders This book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.

Drug and Gene Delivery to the Central Nervous System for Neuroprotection

Drug and Gene Delivery to the Central Nervous System for Neuroprotection
Author: Hari S. Sharma
Publisher: Springer
Total Pages: 237
Release: 2017-06-05
Genre: Medical
ISBN: 3319576968

Download Drug and Gene Delivery to the Central Nervous System for Neuroprotection Book in PDF, Epub and Kindle

This book summarizes the latest research on drug and gene delivery to the central nervous system (CNS). The chapters address safety concerns regarding the nanotechnology that is needed to develop nanomedicine for clinical practice. Particular focus is given to new technologies that have emerged in recent years to deliver therapeutic materials, such as genes, drugs, and other agents using nanotechnologies of diverse origin. This is an ideal book for students, teachers, researchers, and clinicians interested in a deeper understanding of nanotechnological advances in therapeutic medicine. This book also: Broadens readers’ understanding of viral vector gene delivery to the brain for treating neurogenetic diseases as well as targeted gene delivery into the brain using microbubble-facilitated focused ultrasound Covers in detail the latest developments in delivering therapeutic materials, such as siRNA delivery to the brain for treating neurological diseases, neuroprotective effects of gelatin nanoparticles in stroke, and nanowired drug delivery for brain diseases, heat stroke, and CNS injury Enriches understanding of new technologies for delivering therapeutic materials treating Alzheimer’s Disease, including targeted nanodrug delivery through the blood-brain barrier and the superior neuroprotective effects of nanowired drug delivery in Alzheimer’s Disease

Nanomedicine-Based Approaches for the Treatment of Dementia

Nanomedicine-Based Approaches for the Treatment of Dementia
Author: Umesh Gupta
Publisher: Academic Press
Total Pages: 320
Release: 2022-10-11
Genre: Medical
ISBN: 0323859062

Download Nanomedicine-Based Approaches for the Treatment of Dementia Book in PDF, Epub and Kindle

Nanomedicine-Based Approaches for the Treatment of Dementia explores a wide range of promising approaches for the diagnosis and treatment of dementia. The book begins with introductory sections on dementia and brain ailments that are followed by further chapters that discuss detailed information about challenges of drug delivery across the blood-brain barrier as well as the current status. This book helps readers design and develop novel drug delivery systems and devices for the treatment of dementia that take advantage of recent advances in nanomedical technologies. Numerous drug delivery systems have been developed recently for dementia. Unfortunately, most of them are ineffective since dementia is not a single disease. It is an umbrella term for several neurodegenerative conditions which alter brain functions. Due to this, there is an urgent need for innovative technologies/nano drug delivery systems to improve the targeting and delivery of therapeutic as well as diagnostic agents specifically for treating dementia. Explores promising approaches for the diagnosis and treatment of dementia Discusses advances in cutting-edge nanomedical technologies Focuses on the design, synthesis and application of nanocarriers in drug delivery