Molecular Aspects Of Anticancer Drug Dna Interactions C1994
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Author | : Stephen Neidle |
Publisher | : |
Total Pages | : 0 |
Release | : 1993 |
Genre | : Antimitotic agents |
ISBN | : 9780333551158 |
Download Molecular Aspects of Anticancer Drug-DNA Interactions: c1994 Book in PDF, Epub and Kindle
Author | : Stephen Neidle |
Publisher | : CRC Press |
Total Pages | : 386 |
Release | : 1994-05-03 |
Genre | : Medical |
ISBN | : 9780849377730 |
Download Molecular Aspects of Anticancer Drug DNA Interactions Book in PDF, Epub and Kindle
This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
Author | : Neidle |
Publisher | : CRC Press |
Total Pages | : 394 |
Release | : 1993-08-16 |
Genre | : Medical |
ISBN | : 9780849377709 |
Download Molecular Aspects of Anticancer Drug DNA Interaction Book in PDF, Epub and Kindle
This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
Author | : Stephen Neidle (ed) |
Publisher | : |
Total Pages | : |
Release | : 1993 |
Genre | : |
ISBN | : |
Download Molecular Aspects of Anticancer Drug-DNA Interactions-vol1 Book in PDF, Epub and Kindle
Author | : Stephen Neidle |
Publisher | : |
Total Pages | : 424 |
Release | : 1983 |
Genre | : Antimitotic agents |
ISBN | : |
Download Molecular Aspects of Anti-cancer Drug Action Book in PDF, Epub and Kindle
Author | : Awad Momen |
Publisher | : |
Total Pages | : 0 |
Release | : 2022 |
Genre | : Science |
ISBN | : |
Download Anticancer Drugs,Äô Deoxyribonucleic Acid (DNA) Interactions Book in PDF, Epub and Kindle
The deoxyribonucleic acid (DNA) is the molecule of life that controls all the chemical changes that take place in cells. The interaction of drugs with DNA is among the most important aspects of biological studies in drug discovery and pharmaceutical development processes. Moreover, the knowledge of specific targets in rational design of chemotherapeutics is a fundamental factor, principally, for the design of molecules that can be used in the treatment of oncologic diseases. Observing the pre- and postsigns of drug-DNA interaction provides good evidence for the interaction mechanism to be elucidated. Also, this interaction could be used for the quantification of drugs and for the determination of new drugs targeting DNA. Approaches can provide new insight into rational drug design and would lead to further understanding of the interaction mechanism between anticancer drugs and DNA. The intention of this chapter is to provide several examples of anticancer drugs, DNA interaction, and the mechanisms of interaction in order to understand the influence of several interaction factors in the capacity and selectivity of the anticancer drugs to interact with DNA. In addition, different experimental and theoretical approaches to detect and to evaluate the anticancer drugs,Äô interactions with DNA were also discussed.
Author | : Patrick Couvreur |
Publisher | : CRC Press |
Total Pages | : 350 |
Release | : 2003-09-02 |
Genre | : Medical |
ISBN | : 0203305663 |
Download Pharmaceutical Aspects of Oligonucleotides Book in PDF, Epub and Kindle
Oligonucleotides diffuse poorly through biological barriers, including cell membranes. They are also rapidly degraded in vivo by nucleuses. Aiming to improve the administration of compounds, the book studies the development of nucleotide chemistry.
Author | : Ann Arvin |
Publisher | : Cambridge University Press |
Total Pages | : 1325 |
Release | : 2007-08-16 |
Genre | : Medical |
ISBN | : 1139461648 |
Download Human Herpesviruses Book in PDF, Epub and Kindle
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author | : Lihe Zhang |
Publisher | : John Wiley & Sons |
Total Pages | : 477 |
Release | : 2011-08-10 |
Genre | : Medical |
ISBN | : 1118092813 |
Download Medicinal Chemistry of Nucleic Acids Book in PDF, Epub and Kindle
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids presents a thorough overview of nucleic acid chemistry—a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids—such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs—to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy. Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes: In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry A close look at a large range of current topics on nucleic acid chemistry and biology Essential information on the use of nucleic acid drugs to treat diseases like cancer A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research area Thorough in its approach and promising in its message, Medicinal Chemistry of Nucleic Acids probes the new domains of pharmaceutical research—and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.
Author | : Fritz Eckstein Eckstein |
Publisher | : Springer Science & Business Media |
Total Pages | : 387 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642794882 |
Download Nucleic Acids and Molecular Biology Book in PDF, Epub and Kindle
Molecular biology is one of the most rapidly developing and at the same time most exciting disciplines. The key to molecular biology lies in the understanding of nucleic acids - their structure, function, and interaction with proteins. Nucleic Acids and Molecular Biology keeps scientists informed of the explosively growing information and complies with the great interest in this field by offering a continued high standard of review. A substantial part of this volume has been devoted to the analysis of different aspects of nucleic acid-protein-interactions including RNA-protein-interaction.