This book illustrates innovative support-decision models, methods, and advanced automation and robotic technologies aimed at enhancing the overall performance of Warehousing and Material Handling (WMH) in terms of time and space efficiency, service levels, labor safety, and ergonomics. It provides a collection of cutting-edge issues commonly faced in warehousing systems worldwide, along with a structured set of methodologies and technological solutions to address them. Warehousing and Material Handling (WMH) are pivotal processes within supply chain and production systems. They involve the handling, consolidation, and storage of goods such as raw materials, parts, components, and finished products within distribution centers. WMH is also a key component of distribution networks, serving as a hierarchy of facilities dedicated to receiving materials from vendors and shipping to customers while meeting service level and performance targets. The book offers readers the opportunity to explore this topic from multiple knowledge levels and perspectives. At the basic level, it introduces readers to the problems, issues, nomenclature, fundamental models, and methods to support the decision-making process. At an intermediate level, it delves into the state-of-the-art on critical issues in warehousing and material handling systems. Finally, at an advanced level, it delves into the most challenging and recent research and industry issues, addressing both providers and users of WMH solutions and technologies. The book's intended audience includes undergraduate students, graduate students, PhD students, post-doc researchers, scholars, and researchers from academia and industry. It is also relevant for practitioners and managers working in production, logistics, and supply chain environments. The authors' approach is multidisciplinary, with a special focus on logistics, automation, optimization, safety, ergonomics, and the overall sustainability of WMH systems and operations.