Heat Shock Proteins And Whole Body Physiology
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Author | : Alexzander A. A. Asea |
Publisher | : Springer Science & Business Media |
Total Pages | : 431 |
Release | : 2009-12-10 |
Genre | : Medical |
ISBN | : 9048133815 |
Download Heat Shock Proteins and Whole Body Physiology Book in PDF, Epub and Kindle
Heat Shock Proteins and Whole Body Physiology is an exciting new book in the Heat Shock Proteins series which provides the most up-to-date review on novel mechanisms insights into the important role played by heat shock proteins in human physiology. Written by leaders in the field of heat shock protein exercise physiology, neuroscience and aging, the chapters systematically and in a step wise fashion takes the reader through the fascinating mechanisms by which heat shock proteins modulate human disease and pathophysiology and provides answers as to its biological significance to the host. Section I, introduces the readers to the role played by heat shock proteins in various diseases and disorders (Heat Shock Proteins and Disease). Section II, addresses the role heat shock proteins play in psychological disorders including post traumatic stress disorders and learning (Heat Shock Proteins and Psychological Stress). Section III, present a detailed review of the role played by heat shock proteins in exercise physiology (Heat Shock Proteins and Exercise Physiology). This book is a must read for heat shock protein researchers, graduate and postgraduate fellows in the field of Medicine in general and specialities in Excersie Physiology, Neuroscience, Immunology, Aging and Pathology.
Author | : Michael B. Evgen'ev |
Publisher | : Springer |
Total Pages | : 233 |
Release | : 2014-10-24 |
Genre | : Medical |
ISBN | : 9401792356 |
Download Heat Shock Proteins and Whole Body Adaptation to Extreme Environments Book in PDF, Epub and Kindle
For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.
Author | : Alexzander A. A. Asea |
Publisher | : Springer |
Total Pages | : 317 |
Release | : 2018-10-24 |
Genre | : Science |
ISBN | : 3319907255 |
Download Heat Shock Proteins and Stress Book in PDF, Epub and Kindle
The book Heat Shock Proteins and Stress provides the most comprehensive review on contemporary knowledge on the role of HSP in Stress. Using an integrative approach to understanding the regulation of HSP responses, the contributors provide a synopsis of novel mechanisms by which HSP responses are regulated under normal physiological and pathophysiological conditions. Key basic and clinical research laboratories from major universities and academic medical hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Translational Medicine, Clinical Psychologists, Human Physiology, Zoologists, Botanists, Biotechnology, Molecular Medicine, Infectious Diseases Experts and Pathologists.
Author | : Stuart K. Calderwood |
Publisher | : Springer Science & Business Media |
Total Pages | : 399 |
Release | : 2007-09-09 |
Genre | : Medical |
ISBN | : 1402064012 |
Download Heat Shock Proteins in Cancer Book in PDF, Epub and Kindle
Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Author | : Michael B. Evgen'ev |
Publisher | : Springer |
Total Pages | : 218 |
Release | : 2014-10-29 |
Genre | : Medical |
ISBN | : 9789401792363 |
Download Heat Shock Proteins and Whole Body Adaptation to Extreme Environments Book in PDF, Epub and Kindle
For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.
Author | : Alexzander A A Asea |
Publisher | : Springer |
Total Pages | : 471 |
Release | : 2018-05-01 |
Genre | : Medical |
ISBN | : 3319747150 |
Download Regulation of Heat Shock Protein Responses Book in PDF, Epub and Kindle
This books provides the most up-to-date reviews on current advances in our understanding of the regulation of heat shock protein responses. Key basic scientists and clinical research laboratories from major universities, academic medical centers and pharmaceutical companies around the world have contributed chapters that review present research activity and importantly project this field into the future. For easy readability, the book is sub divided into four sections, including, Section I - HSP and Stress Responses; Section II - Chaperone Functions of HSP; Section III - HSP in Human Diseases; Section IV - Prognosis & Diagnosis of HSP. The book is a must read for researchers involved in biomedical research, drug discovery and design to improve human health.
Author | : Rakesh C. Kukreja |
Publisher | : CRC Press |
Total Pages | : 145 |
Release | : 2000-08-01 |
Genre | : Science |
ISBN | : 1498712665 |
Download Heat Shock Proteins in Myocardial Protection Book in PDF, Epub and Kindle
Myocardial ischemic syndromes pose a major medical problem and a significant economic health care concern. Reperfusion, although used in the clinical arena as essential to the survival of acutely ischemic heart muscle carries with it the risk of reperfusion injury. Therefore the salvage of additional myocardium is highly desirable.
Author | : Peter Csermely |
Publisher | : Springer Science & Business Media |
Total Pages | : 218 |
Release | : 2007-08-09 |
Genre | : Science |
ISBN | : 0387399755 |
Download Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks Book in PDF, Epub and Kindle
This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.
Author | : Clark M. Blatteis |
Publisher | : World Scientific |
Total Pages | : 316 |
Release | : 1998 |
Genre | : Science |
ISBN | : 9789810231729 |
Download Physiology and Pathophysiology of Temperature Regulation Book in PDF, Epub and Kindle
This is a user-friendly monograph designed for medical students as well as graduate students and postdoctoral trainees in medicine and other health-related sciences who need a comprehensive overview of thermoregulation. It presents the bases of the modern concepts in thermal physiology and pathophysiology, bringing together the disciplines encompassed by this highly integrative field ? physiology, anatomy, biophysics, molecular and cellular biology, pharmacology, neuroscience, pathology, medicine, and others ? into a clear and concise form that can be read comfortably in a relatively short time. This text was conceived by the Commission on Thermal Physiology of the International Union of Physiological Sciences in response to its concern over the inadequate and outdated coverage of this topic in traditional textbooks. The membership of this Commission comprises international experts in each of the subfields of thermal physiology, with extensive research and teaching experience in their respective specialties. They are the authors of the chapters of this indispendable textbook.
Author | : Raluca Maria Fratila |
Publisher | : Elsevier |
Total Pages | : 384 |
Release | : 2018-11-30 |
Genre | : Science |
ISBN | : 0128139293 |
Download Nanomaterials for Magnetic and Optical Hyperthermia Applications Book in PDF, Epub and Kindle
Nanomaterials for Magnetic and Optical Hyperthermia Applications focuses on the design, fabrication and characterization of nanomaterials (magnetic, gold and hybrid magnetic-gold nanoparticles) for in vitro and in vivo hyperthermia applications, both as standalone and adjuvant therapy in combination with chemotherapy. The book explores the potential for more effective cancer therapy solutions through the synergistic use of nanostructured materials as magnetic and optical hyperthermia agents and targeted drug delivery vehicles, while also discussing the challenges related to their toxicity, regulatory and translational aspects. In particular, the book focuses on the design, synthesis, biofunctionalization and characterization of nanomaterials employed for magnetic and optical hyperthermia. This book will be an important reference resource for scientists working in the areas of biomaterials and biomedicine seeking to learn about the potential of nanomaterials to provide hyperthermia solutions. Explores the design of efficient nanomaterials for hyperthermia applications, allowing readers to make informed materials selection decisions Discusses the biofunctionalization of a range of nanomaterials and their interaction with living systems Provides an overview of the current clinical applications of nanomaterials in hyperthermia treatment