This special issue of the Journal of Latin American Theology is a collaboration with Memoria Indígena on Indigenous theology. The explanatory preface by guest editor Drew “Andrés” Jennings-Grisham sets the stage for why Indigenous theologies and contributions are so needed by the global church. Toward that end, this issue of JLAT features more Indigenous voices than any of our previous publications. These voices reach us through poetry (Francisco Pérez Alonzo and Jocabed Solano), a devotional reflection (Benita Simón Mendoza), comments on Bible translation (Sabayu), a documentary film on weaving (reviewed by Samuel Lagunas), and the final summary document of a 2021 Memoria Indígena gathering on theological education. They come through articles, an interview, and a group response that challenge the church to decolonialize its theology and practice (Juana L. Condori Quispe, Fernando Quicaña, Drew Jennings-Grisham, and the FTL’s 3i Working Group). They come through a historical review of mission work (Azucena Rosal), of Indigenous social movements (Julián Guamán Gualli), and of FTL publications (Drew Jennings-Grisham). Two master’s theses have been summarized and adapted herein. One draws on Andean Kichwa spirituality to shape a holistic Christian theology of life (María Alejandra Andrade) and the other develops a hermeneutical proposal for dialoguing with scriptural narratives from, with, and for a specific Indigenous community (Jocabed Solano). We trust that engaging with these articles will lead us all into more mutual, interdependent, and responsible relationships in the power of Christ’s Spirit, the Ruah.