Drug Induced Cardiotoxicity Mechanism Prevention And Management
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Author | : Mina T. Kelleni |
Publisher | : |
Total Pages | : |
Release | : 2018 |
Genre | : Medicine |
ISBN | : |
Download Drug Induced Cardiotoxicity: Mechanism, Prevention and Management Book in PDF, Epub and Kindle
Drug-induced cardiotoxicity is a major adverse effect that has been encountered for some clinically important drugs especially antineoplastic agents. This toxicity has previously led to the post-marketing withdrawal of numerous pharmacologically active drugs and limits the efficacy of other clinically useful ones. Currently, assessing the cardiotoxicity potential is a crucial parameter in drug development, and many models have been established to facilitate its prediction to avoid such toxicity. In this chapter, we will briefly discuss the mechanism of drug-induced cardiotoxicity, risk factors, how to prevent, early detection and/or management from a pharmacological and toxicological point of view.
Author | : Wenyong Tan |
Publisher | : BoD – Books on Demand |
Total Pages | : 164 |
Release | : 2018-11-14 |
Genre | : Medical |
ISBN | : 1789842379 |
Download Cardiotoxicity Book in PDF, Epub and Kindle
Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.
Author | : Feng Sun |
Publisher | : Frontiers Media SA |
Total Pages | : 156 |
Release | : 2023-08-01 |
Genre | : Medical |
ISBN | : 2832530931 |
Download Drug-induced cardiotoxicity: Identification, assessment, prevention and management Book in PDF, Epub and Kindle
Author | : Carmen Salavastru |
Publisher | : Springer Nature |
Total Pages | : 494 |
Release | : 2021-03-10 |
Genre | : Medical |
ISBN | : 3030547795 |
Download Skin and the Heart Book in PDF, Epub and Kindle
This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment. Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa. Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.
Author | : Susan Currie |
Publisher | : Frontiers Media SA |
Total Pages | : 161 |
Release | : 2022-10-11 |
Genre | : Medical |
ISBN | : 2832502105 |
Download Anti-Cancer Drug-Induced Cardiotoxicity Book in PDF, Epub and Kindle
Author | : Ajay Vora |
Publisher | : Springer |
Total Pages | : 345 |
Release | : 2017-04-21 |
Genre | : Medical |
ISBN | : 3319397087 |
Download Childhood Acute Lymphoblastic Leukemia Book in PDF, Epub and Kindle
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author | : Wenyong Tan |
Publisher | : |
Total Pages | : 162 |
Release | : 2018 |
Genre | : Diseases of the circulatory (Cardiovascular) system |
ISBN | : 9781789842388 |
Download Cardiotoxicity Book in PDF, Epub and Kindle
Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.
Author | : James A. Dykens |
Publisher | : Wiley-Interscience |
Total Pages | : 0 |
Release | : 2008-09-22 |
Genre | : Science |
ISBN | : 9780470111314 |
Download Drug-Induced Mitochondrial Dysfunction Book in PDF, Epub and Kindle
This is the definitive, one-stop resource on preclinical drug evaluation for potential mitochondrial toxicity, addressing the issue upfront in the drug development process. It discusses mitochondrial impairment to organs, skeletal muscle, and nervous systems and details methodologies used to assess mitochondria function. It covers both in vitro and in vivo methods for analysis and includes the latest models. This is the authoritative reference on drug-induced mitochondrial dysfunction for safety assessment professionals in the pharmaceutical industry and for pharmacologists and toxicologists in both drug and environmental health sciences.
Author | : Stephan Gielen |
Publisher | : European Society of Cardiology |
Total Pages | : 369 |
Release | : 2015 |
Genre | : Medical |
ISBN | : 0199656657 |
Download The ESC Textbook of Preventive Cardiology Book in PDF, Epub and Kindle
"EACPR, European Association for Cardiovascular Prevention and Rehabilitation -- European Society of Cardiology."
Author | : Patrizio Lancellotti |
Publisher | : Academic Press |
Total Pages | : 483 |
Release | : 2016-11-11 |
Genre | : Medical |
ISBN | : 0128026472 |
Download Anticancer Treatments and Cardiotoxicity Book in PDF, Epub and Kindle
Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment