Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2
Author: Susanne Zeilinger
Publisher: Springer
Total Pages: 263
Release: 2015-06-15
Genre: Science
ISBN: 1493925318
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​Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites
Author: Juan-Francisco Martín
Publisher: Springer
Total Pages: 357
Release: 2014-09-09
Genre: Science
ISBN: 1493911910
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This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.

Laboratory Protocols in Fungal Biology

Laboratory Protocols in Fungal Biology
Author: Vijai Kumar Gupta
Publisher: Springer Science & Business Media
Total Pages: 608
Release: 2012-12-09
Genre: Science
ISBN: 1461423562
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Laboratory Protocols in Fungal Biology presents the latest techniques in fungal biology. This book analyzes information derived through real experiments, and focuses on cutting edge techniques in the field. The book comprises 57 chapters contributed from internationally recognised scientists and researchers. Experts in the field have provided up-to-date protocols covering a range of frequently used methods in fungal biology. Almost all important methods available in the area of fungal biology viz. taxonomic keys in fungi; histopathological and microscopy techniques; proteomics methods; genomics methods; industrial applications and related techniques; and bioinformatics tools in fungi are covered and complied in one book. Chapters include introductions to their respective topics, list of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting. Each chapter is self-contained and written in a style that enables the reader to progress from elementary concepts to advanced research techniques. Laboratory Protocols in Fungal Biology is a valuable tool for both beginner research workers and experienced professionals. Coming Soon in the Fungal Biology series: Goyal, Manoharachary / Future Challenges in Crop Protection Against Fungal Pathogens Martín, García-Estrada, Zeilinger / Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites Zeilinger, Martín, García-Estrada / Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites, Volume 2 van den Berg, Maruthachalam / Genetic Transformation Systems in Fungi Schmoll, Dattenbock / Gene Expression Systems in Fungi Dahms / Advanced Microscopy in Mycology

Fungal Secondary Metabolism

Fungal Secondary Metabolism
Author: Nancy P. Keller
Publisher: Humana Press
Total Pages: 302
Release: 2016-05-01
Genre: Medical
ISBN: 9781493959600
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This Methods in Molecular Biology volume provides key methodologies for accessing and exploiting natural product information provided by the genomes of filamentous fungi. Includes materials and reagents lists, step-by-step protocols and troubleshooting tips."

Applied Molecular Genetics of Filamentous Fungi

Applied Molecular Genetics of Filamentous Fungi
Author: J.R. Kinghorn
Publisher: Springer Science & Business Media
Total Pages: 284
Release: 1992-08-31
Genre: Medical
ISBN: 9780751400588
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The filamentous fungi are perhaps unique in the diversity of their metabolic activities. This includes biosynthetic as well as degradative activities, many is to provide an of which are of industrial interest. The objective of this text up-to-date and broad review which emphasizes the genetic and molecular biological contribution in the field of fungal biotechnology. This text begins with an overview of the tools and methodologies involved which, to a large extent, have been developed in the model filamentous fungus Aspergillus nidulans and subsequently have been extended to commercially important fungi. This is followed by a chapter which provides a compilation of genes isolated from commercial fungi and their present status with respect to structure, function and regulation. Chapters 3 and 4 highlight the degradative powers of filamentous fungi. First, a discussion of what is known regarding the molecular genetics of fungi and the genes and enzymes involved in the beverage and food industries. This has an oriental flavour, reflecting the tremendous importance of fungi in traditional Chinese and Japanese food production. An account of lignocellulose degradation by filamentous fungi follows, illustrating the potential of fungi to utilize this substance as a renewable energy source. The ability of fungi to produce high-value foreign proteins is reviewed in chapters 5 and 6. Chymosin production, in particular, represents a good example of high-level yields being obtained, such as to warrant commercial production.

Physiology and Genetics

Physiology and Genetics
Author: Timm Anke
Publisher: Springer
Total Pages: 473
Release: 2018-02-01
Genre: Science
ISBN: 3319717405
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In the last few decades, DNA-based tools for the investigation of fungal taxonomy, signal transduction and regulation, differentiation processes and biosynthetic potential have accelerated advances in our understanding of the Mycota. This completely updated and revised second edition presents a selection of exciting issues involving basic and applied aspects of fungal physiology and genetics. In 14 chapters, respected experts provide an overview of traditional, topical and future aspects of basic fungal principles and potential applications in biotechnology. The contributions will bring scientists up-to-date on the latest developments, and help students familiarize themselves with the different topics.

The Fungal Kingdom

The Fungal Kingdom
Author: Joseph Heitman
Publisher: John Wiley & Sons
Total Pages: 1136
Release: 2020-07-10
Genre: Medical
ISBN: 1555819583
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Fungi research and knowledge grew rapidly following recent advances in genetics and genomics. This book synthesizes new knowledge with existing information to stimulate new scientific questions and propel fungal scientists on to the next stages of research. This book is a comprehensive guide on fungi, environmental sensing, genetics, genomics, interactions with microbes, plants, insects, and humans, technological applications, and natural product development.

Fungal Genomics

Fungal Genomics
Author:
Publisher: Elsevier
Total Pages: 433
Release: 2004-02-25
Genre: Science
ISBN: 0080527469
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Research in the genomics of a handful of fungi has matured at an unprecedented rate allowing comprehensive review. Developments in fungal genomics should be of great significance to new strategies in fields where disciplinary crossovers of fungal genomics, genes and their regulation, expression, and engineering will have a strong impact in dealing with agriculture, foods, natural resources, life sciences, biotechnology, informatics, metabolomics, pharmaceuticals and bioactive compounds. This volume analyzes the commonly used molecular markers systems, and elaborates the development of biochemical genetics, which provides a model system that established the relationship between genes and enzymes. Current knowledge about the genomic and genetic variability of Candida albicans, the polymorphic fungus that is an opportunistic human pathogen of increasing medical importance, has been covered in detail. Current understanding of the genetics and functional genomic analysis of the most important fungal pathogens of staple food crops, rice and wheat among others is covered including chapters dealing with the genomics of economically important fungi such asMagnaporthe grisea, Aspergillus, Fusarium, Penicillium, Trichoderma, Rhizoctonia, Mycosphaerella graminicola, and entomopathogenic fungi. With several thousand recent citations, it is hoped that volume four will serve as a useful reference for knowledgeable veterans and beginners as well as those crossing disciplinary boundaries into the exciting field of biotechnology, genomics and bioinformatics of fungi.

Applied Molecular Genetics of Fungi

Applied Molecular Genetics of Fungi
Author: British Mycological Society. Symposium
Publisher: Cambridge University Press
Total Pages: 204
Release: 1991-10-31
Genre: Medical
ISBN: 9780521415712
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The interactions of fungi with mankind are both beneficial and harmful and are deeply rooted in the history of human society and agriculture. This book highlights the ways in which fungal recombinant DNA technology is being used in species of economic importance.