Exercise immunology is a discipline at the nexus of exercise physiology and immunology that aims to characterise the effects of exercise on the immune system in health and disease. This new edition of Exercise Immunology begins by providing an evidence‐based introduction to the effects that individual bouts of exercise and exercise training have on the characteristics and functioning of the immune system. In addition to introducing the immune system and summarising how different forms of exercise affect the characteristics and functioning of the immune system, this new and fully revised edition will explore exercise immunology in the context of immune ageing, cancer, autoimmune diseases and cardiometabolic disease. In addition, the authors discuss other factors that impact immune health, such as nutrition and environmental stressors, and explain the physiological basis of how exercise changes immune function across the healthspan and lifespan. This book is written by leading exercise immunologists and is structured to provide a suggested curriculum of an exercise immunology degree component. Every chapter includes summaries of current and up‐to‐date research and offers practical guidelines to translate laboratory‐based information into clinical settings. This textbook is essential for any exercise immunology degree component or advanced exercise physiology degree and will be vital reading for students in exercise and biological sciences and clinicians and researchers interested in the therapeutic applications of exercise.