Amiloride and Epithelial Sodium Transport
Author | : Alan W. Cuthbert |
Publisher | : |
Total Pages | : 184 |
Release | : 1979 |
Genre | : |
ISBN | : 9783541703111 |
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Author | : Alan W. Cuthbert |
Publisher | : |
Total Pages | : 184 |
Release | : 1979 |
Genre | : |
ISBN | : 9783541703111 |
Author | : |
Publisher | : Academic Press |
Total Pages | : 425 |
Release | : 1999-05-04 |
Genre | : Science |
ISBN | : 0080585183 |
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations. Summarizes current state of amiloride-sensitive sodium channel field Analyzes structure-function of epithelial sodium channels Discusses immunolocalization of epithelial sodium channels Examines hormonal regulation of sodium channels Discusses sodium channels in lymphocytes, kidney, and lung Considers mechanosensitivity of sodium channels Provides ideas on sodium channels and disease
Author | : |
Publisher | : |
Total Pages | : 0 |
Release | : 1979 |
Genre | : |
ISBN | : |
Author | : Edward J. Cragoe |
Publisher | : Wiley-VCH |
Total Pages | : 414 |
Release | : 1992 |
Genre | : Amiloride |
ISBN | : |
Author | : Venkataramana K Sidhaye |
Publisher | : Academic Press |
Total Pages | : 277 |
Release | : 2017-03-09 |
Genre | : Medical |
ISBN | : 0128038810 |
Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences
Author | : Alan William Cuthbert |
Publisher | : Urban & Schwarzenberg |
Total Pages | : 208 |
Release | : 1979 |
Genre | : Medical |
ISBN | : |
Author | : Robert J. Alpern |
Publisher | : Elsevier |
Total Pages | : 2922 |
Release | : 2007-10-10 |
Genre | : Science |
ISBN | : 0080559506 |
A classic nephrology reference for over 20 years, Seldin & Giebisch’s The Kidney, is the acknowledged authority on renal physiology and pathophysiology. The fourth edition follows the changed focus of nephrology research to the study of how individual molecules work together to affect cellular and organ function, emphasizing the mechanisms of disease. With over 40 new chapters and over 1000 illustrations, this edition offers the most in-depth discussion anywhere of the physiologic and pathophysiologic processes of renal disease. Comprehensive, authoritative coverage progresses from molecular biology and cell physiology to clinical issues regarding renal function and dysfunction. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch’s The Kidney is your number one source for information. * Offers the most comprehensive coverage of fluid and electrolyte regulation and dysregulation in 51 completely revised chapters unlike Brenner & Rector's The Kidney which devotes only 7 chapters to this topic.* Includes 3 sections, 31 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Brenner & Rector's only devotes 5 chapters to these topics.* Previous three editions edited by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology. The title for the fourth edition has been changed to reflect their considerable work on previous editions and they have also written the forward for this edition. * Over 20 million adults over age 20 have chronic kidney disease with the number of people diagnosed doubling each decade making it America's ninth leading cause of death.
Author | : N.K. Wills |
Publisher | : Springer Science & Business Media |
Total Pages | : 366 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 9400914954 |
Building from general principles, the authors clearly explain the fundamental role of epithelia in plasma electrolyte and water balance. Emphasis is placed on experimental approaches and methodology. A comprehensive glossary of terms is included.
Author | : |
Publisher | : |
Total Pages | : |
Release | : 2014 |
Genre | : |
ISBN | : |
Author | : Shin-Ho Chung |
Publisher | : Springer Science & Business Media |
Total Pages | : 657 |
Release | : 2007-11-13 |
Genre | : Science |
ISBN | : 0387689192 |
This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and biosensors, as well as advanced undergraduate and graduate students in biology and the physical sciences.