Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA

Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA
Author: Stephen J. Peroutka
Publisher: Springer Science & Business Media
Total Pages: 252
Release: 2012-12-06
Genre: Medical
ISBN: 1461314852

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The variety of viewpoints expressed in this book illustrate the many contro versies surrounding MDMA [1]. On the one hand, the proponents ofMDMA use believe this agent offers a unique psychoactive effect that may have important clinical applications, especially in the field of psychotherapy. On the other hand, the scientific data concerning the neurotoxic effects of the drug are unequivocal. The most striking feature of the human information of MDMA is the paucity of data that has been generated on the drug since it was patented in 1914. As pointed out by Beck (Chapter 6) and others, a clear need exists for better epidemiological and clinical data on MDMA. In the absence of such data, arguments both for and against the cotinued use ofMDMA with humans will be difficult to support. Unfortunately, the currently available data must be used to develop rational policies for potential human users of MDMA. At the present time, there are no data indicating that recreational doses of MDMA permanently damage the human brain. Nonetheless, based on a review of the contents of this book as well as on informal discussions with approximately 200 recreational users of MDMA, the following personal observations suggest that MDMA is radically different from other recreational drugs.

Pursuit of Ecstasy

Pursuit of Ecstasy
Author: Jerome Beck
Publisher: State University of New York Press
Total Pages: 258
Release: 1994-03-08
Genre: Social Science
ISBN: 0791496090

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The authors have produced the first "on the ground" study (not just clinical or chemical) of MDMA (3, 4-methylenedioxymethamphetamine), or "ecstasy" as it is frequently designated. A psychoactive substance related to both the amphetamines and mescaline, MDMA has become popular in recent years as one of the new "designer" drugs. First used in therapeutic treatment, its recreational or street use has increased in recent years. The authors track the efforts (with psychiatrists and researchers in opposition) of the DEA to ban the drug.

Beyond Ecstasy

Beyond Ecstasy
Author: Ben Sessa
Publisher:
Total Pages: 0
Release: 2024-08-07
Genre: Health & Fitness
ISBN: 9781022903340

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Breaking Through the Stigma: MDMA-Assisted Psychotherapy and the Path to Healing The story of MDMA is one of remarkable transformation. Often known for its recreational use under the moniker 'ecstasy, ' this drug has garnered both cultural fascination and stigmatization. However, buried beneath the layers of controversy, lies an untapped therapeutic potential rapidly gaining scientific credence: the employment of MDMA in clinical settings, particularly for treating post-traumatic stress disorder (PTSD) and other mental health conditions. 'Beyond Ecstasy: The Hidden Therapeutic Potential of MDMA' is a thoughtfully curated collection of scientific journal articles that investigates this transformative journey from a synthesized molecule to a potential healing agent. The book reviews the neurobiological mechanisms that set MDMA apart, showcasing its ability to foster empathy and emotional connection, critical elements that enable profound therapeutic experiences. It examines the human stories of relief and reconnection emerging from clinical trials. From enhancing relational therapies by improving communication and intimacy, to demonstrating significant cost-effectiveness and long-term benefits, this compilation covers the multifaceted implications of MDMA-assisted psychotherapy. Key articles spotlight randomized, double-blind, placebo-controlled trials, elucidating the promising clinical outcomes against PTSD and the safety concerns evaluated through extensive studies. The book takes an in-depth look at the broader societal impacts, including healthcare savings and quality of life improvements, urging a re-evaluation of how psychoactive substances are perceived and utilized within mental health treatment paradigms. As you journey through these compelling studies, 'Beyond Ecstasy' not only aims to educate but also to inspire hope. It presents a bold narrative that challenges conventional perceptions and opens doors to new beginnings for those underserved by current treatments, highlighting a path forward to dismantling long-held stigmas. Quality Research Publishing is dedicated to making knowledge more accessible to the general public by curating a topical compilation of the latest research on various subjects and providing plain language summaries. Each of the articles in this book is available individually and digitally without cost. However, we believe it is important for the contextualizing and sharing of educational and scientific work to curate this research in a way that is understandable and helpful to the average person seeking deeper knowledge of a particular subject. The research articles compiled for this book were published under a permissive Creative Commons license, are in the public domain, or have no copyright restrictions, permitting their use in this book. If you have questions about the licensing of any article, please visit qualityresearchpublishing.com.

The Love Drug

The Love Drug
Author: Richard S. Cohen
Publisher: Routledge
Total Pages: 200
Release: 1998
Genre: Language Arts & Disciplines
ISBN:

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Cohen, a researcher whose work on MDMA has been published in several scholarly journals, gives a balanced and impartial view of the drug's past and present history, covering the structural significance, legal controversy, and adverse reactions surrounding it. Accessible to general readers and partiers as well as researchers, educators, and medical professionals. Paper edition (unseen), $19.95. Annotation copyrighted by Book News, Inc., Portland, OR

Manifesting Minds

Manifesting Minds
Author: Rick Doblin, Ph.D.
Publisher: North Atlantic Books
Total Pages: 305
Release: 2014-01-07
Genre: Body, Mind & Spirit
ISBN: 1583947272

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Featuring essays and interviews with Timothy Leary, Aldous Huxley, Ram Dass, Albert Hofmann, Alexander (Sasha) Shulgin, Daniel Pinchbeck, Tim Robbins, Arne Naess, and electronic musician Simon Posford, as well as groundbreaking research and personal accounts, this one-of-a-kind anthology is a "best of" collection of articles and essays published by the Multidisciplinary Association for Psychedelic Studies (MAPS). Topics include the healing use of marijuana and psychedelics--including MDMA, ibogaine, LSD, and ayahuasca--for PTSD, anxiety, depression, and drug addiction, as well as positive effects of these substances in the realm of the arts, family, spirituality, ecology, and technology. Among many other thought-provoking and mind-opening pieces are the following: • "On Leary and Drugs at the End," by Carol Rosen and Vicki Marshall • "Psychedelic Rites of Passage," by Ram Dass • "To Be Read at the Funeral," by Albert Hofmann • "Another Green World: Psychedelics and Ecology," by Daniel Pinchbeck • "Psychedelics and Species Connectedness," by Stanley Krippner, PhD • "Huxley on Drugs and Creativity," by Aldous Huxley • "Psychedelics and the Deep Ecology Movement: A Conversation with Arne Naess," by Mark A. Schroll, PhD, and David Rothenberg • "Psychedelic Sensibility," by Tom Robbins • "Electronic Music and Psychedelics: An Interview with Simon Posford of Shpongle," by David Jay Brown • "How Psychedelics Informed My Sex Life and Sex Work," by Annie Sprinkle • "Consideration of Ayahuasca for the Treatment of Posttraumatic Stress Disorder," by Jessica Nielson, PhD, and Julie Megler, MSN, NP-BC • "Psychedelics and Extreme Sports," by James Oroc • "Youth and Entheogens: A Modern Rite of Passage?," by Andrei Foldes with Amba, Eric Johnson, et al. • "Diary of an MDMA Subject," by Anonymous • "Dimethyltryptamine: Possible Endogenous Ligand of the Sigma-1 Receptor?," by Adam L. Halberstadt • "Lessons from Psychedelic Therapy," by Richard Yensen, PhD • "Psychosomatic Medicine, Psychoneuroimmunology, and Psychedelics," by Ana Maqueda • "Talking with Ann and Sasha Shulgin about the Existence of God and the Pleasures of Sex and Drugs," by Jon Hanna and Silvia Thyssen

MDMA Case Study. A Case for Decriminalization or Prohibition?

MDMA Case Study. A Case for Decriminalization or Prohibition?
Author: Alexander Syder
Publisher: GRIN Verlag
Total Pages: 19
Release: 2015-09-16
Genre: Medical
ISBN: 3668046875

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Essay from the year 2015 in the subject Medicine - Neurology, Psychiatry, Addiction, grade: Merit, Sheffield Hallam University (Sheffield Hallam University), course: MSc Psychology, language: English, abstract: MDMA has become one of the most popular, recreational drugs in the westernized world. Although the use of MDMA has become increasingly widespread, there exists a serious debate amongst the psychiatric researchers as to whether MDMA (ecstasy) is a potentially dangerous and lethal drug to the individual using the substance. There is however an opposing argument amongst a group of researchers that MDMA has therapeutic benefits that can be used for self-healing, alleviating social anxiety and problems with social integration in a psychotherapeutic environment. The media and state politicians in western countries have however been pursuing a discourse of promoting MDMA as the same status as cocaine and heroin, with the same psychological and physiological properties; the reason is partially political with the populist stance of political parties to be seen as tough on drugs, often referred to as the ‘War on Drugs’ coined by President Nixon in 1971. There is a divide therefore on the issue of MDMA as to whether this is a debate on the nature of the drug and its effects. Studies have been aimed at defining ecstasy from a premise of whether the effects are bad or good, studies leaning towards one of the observations typically rather than allowing for equal debate; the research can become political as opposed to unbiased scientific research, as Meyer’s (2013) argues research into ecstasy has come from its most vociferous detractors and the most ardent supporters. The studies of beneficial effects are nonetheless increasingly limited, with little opportunity to test this proposed hypothesis. For instance in the US, the DEA has categorized MDMA as a Schedule 1 drug, a drug that through its classification is considered incredibly dangerous with high federal penalties for the possession and supply of the drug.

A Dose of Hope

A Dose of Hope
Author: Dan Engle
Publisher:
Total Pages: 334
Release: 2021-07-02
Genre:
ISBN: 9781544521039

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MDMA-assisted therapy for PTSD is in the final stages of FDA testing. Clinical trials are reporting a 70 percent cure rate for a condition that claims thousands of lives globally every day-hundreds in the US alone. But until it's fully legalized, MDMA is still a Schedule I drug, saddled with years of misunderstanding, misinformation, and misuse. In this groundbreaking, informative, and easy-to-read book, Dr. Dan Engle shows you the treatment through the eyes of a fictional patient so you can see how it works without ever setting foot in a doctor's office. Follow in-depth conversations between doctor and patient, learn about the history of MDMA-assisted therapy, understand how and why it helps, and experience the process for yourself-without ever having to take anything.  The treatment presented here is a synthesis of the real experiences and stunning results happening today in trials around the world. Whether you or a loved one suffer from PTSD, or you just want to heal something that's keeping you from living your best life, don't miss A Dose of Hope.

Ecstasy

Ecstasy
Author: Alan Philmann
Publisher: Createspace Independent Publishing Platform
Total Pages: 64
Release: 2016-09-11
Genre:
ISBN: 9781537614656

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Ecstasy is an extremely popular drug among youth, it is extremely is easy to get, and it is not complicated to make. Ecstasy use and the manufacture of it are illegal, but there are a couple of good reasons to synthesize your own MDMA or MDA. The use of ecstasy, specifically in high quantities, can lead to neurotoxicity and memory deficits. Most ecstasy users are polydrug users, so the drug is not typically abused. This book discusses the physiological effects of the drug, how the demographics of the drug's use have changed, and how to produce ecstasy. Despite being made illegal in the 1970s by most Western governments, ecstasy still remains an extremely popular drug today, and it is currently be used in laboratory settings with other psychoactive drugs in conjunction with cognitive therapy to treat individuals suffering from PTSD.

Psychobiology of MDMA

Psychobiology of MDMA
Author: A. C. Parrott
Publisher:
Total Pages: 0
Release: 2009-11-18
Genre: Central nervous system
ISBN: 9783805593144

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The effects of recreational MDMA or ecstasy users was one of the main topic discussed during the international MDMA conference held in Melbourne 2008. In this special issue interesting papers on ecstasy dependence, impairments in thermoregulation and overheating, cognitive deficits, impulsivity and depression, the contributory role of the neurohormone oxytocin, and roadside testing of MDMA in car drivers are presented. Animal models of neurotoxicity, patterns of emergency hospital admission, the self-administration of MDMA in laboratory animals, and drug interactions between MDMA and alcohol are also discussed as well as papers about memory changes in working and information processing, and the memory consolidation effect of sleep. Further articles cover the role of the energetic stress neurohormone cortisol, and the use of the Internet for conducting large-scale studies with illicit drug users. Psychopharmacologists, pharmacologists, psychiatrists and psychologists will find valuable information about the latest research into the psychobiological effects of recreational MDMA or ecstasy.